Selenium, selenoprotein P, and Alzheimer's disease: is there a link?
The essential trace element, selenium (Se), is crucial to the brain but it may be potentially neurotoxic, depending on dosage and speciation; Se has been discussed for decades in relation to Alzheimer's disease (AD).
N. Solovyev +5 more
semanticscholar +1 more source
Role of selenium in the pathophysiology of cardiorenal anaemia syndrome
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai +2 more
wiley +1 more source
Sex-specific and inter-individual differences in biomarkers of selenium status identified by a calibrated ELISA for selenoprotein P [PDF]
Selenoprotein P (SELENOP) is a liver-derived transporter of selenium (Se) in blood, and a meaningful biomarker of Se status. Se is an essential trace element for the biosynthesis of enzymatically-active selenoproteins, protecting the organism from ...
Hybsier, Sandra +10 more
core +1 more source
Disruption of Selenium Handling During Puberty Causes Sex-Specific Neurological Impairments in Mice
Selenium is an essential trace element linked to normal development and antioxidant defense mechanisms through its incorporation into selenoproteins via the amino acid, selenocysteine (Sec).
Penny M. Kremer +3 more
doaj +1 more source
Selenoproteins and cardiovascular stress [PDF]
SummaryDietary selenium (Se) is an essential micronutrient that exerts its biological effects through its incorporation into selenoproteins. This family of proteins contains several antioxidant enzymes such as the glutathione peroxidases, redox-regulating enzymes such as thioredoxin reductases, a methionine sulfoxide reductase, and others.
Aaron H, Rose, Peter R, Hoffmann
openaire +2 more sources
Selenoproteins in mammalian spermatogenesis:role of the nuclear GPx4 [PDF]
The selenoprotein Phospholipid Hydroperoxide Glutathione Peroxidase (PHGPx/GPx4) is an enzyme unique among the various GPxs, because it is able to use protein thiols, beside glutathione, The GPx4 gene encodes for three isoforms having different ...
Maccari, Irene
core
Atomic spectrometry update. Clinical and biological materials, foods and beverages [PDF]
This review discusses developments in elemental mass spectrometry, atomic absorption, emission and fluorescence, XRF and LIBS, as applied to the analysis of specimens of clinical interest, foods and beverages.
Day, Martin P. +5 more
core +2 more sources
Selenium and selenoprotein P1 levels are related to primary open-angle glaucoma [PDF]
Background: Glaucoma is a highly prevalent eye disease related to optic nerve lesions and visual field defects. Primary Open-Angle Glaucoma (POAG) is a type of glaucoma that occurs frequently with unknown etiology.
Najafi Mohammad +4 more
doaj
Selenoprotein genetic variations and suboptimal selenium (Se) levels may contribute to the risk of colorectal cancer (CRC) development. We examined the association between CRC risk and genotype for single nucleotide polymorphisms (SNPs) in selenoprotein ...
V. Fedirko +50 more
semanticscholar +1 more source
Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems
Main nanocarriers employed to enhance the bioavailability and transport of organoselenium compounds. The image illustrates the key interaction forces that stabilize these organoselenium species in solution, enabling their application in drug delivery systems, catalysis, photoelectronic devices, and sensing technologies. In recent years, publications on
Romelly Eugenia Rojas Ramírez +3 more
wiley +1 more source

