Results 91 to 100 of about 27,808 (261)

Selenium, selenoprotein P, and Alzheimer's disease: is there a link?

open access: yesFree Radical Biology & Medicine, 2018
The essential trace element, selenium (Se), is crucial to the brain but it may be potentially neurotoxic, depending on dosage and speciation; Se has been discussed for decades in relation to Alzheimer's disease (AD).
N. Solovyev   +5 more
semanticscholar   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai   +2 more
wiley   +1 more source

Sex-specific and inter-individual differences in biomarkers of selenium status identified by a calibrated ELISA for selenoprotein P [PDF]

open access: yes, 2017
Selenoprotein P (SELENOP) is a liver-derived transporter of selenium (Se) in blood, and a meaningful biomarker of Se status. Se is an essential trace element for the biosynthesis of enzymatically-active selenoproteins, protecting the organism from ...
Hybsier, Sandra   +10 more
core   +1 more source

Disruption of Selenium Handling During Puberty Causes Sex-Specific Neurological Impairments in Mice

open access: yesAntioxidants, 2019
Selenium is an essential trace element linked to normal development and antioxidant defense mechanisms through its incorporation into selenoproteins via the amino acid, selenocysteine (Sec).
Penny M. Kremer   +3 more
doaj   +1 more source

Selenoproteins and cardiovascular stress [PDF]

open access: yesThrombosis and Haemostasis, 2015
SummaryDietary selenium (Se) is an essential micronutrient that exerts its biological effects through its incorporation into selenoproteins. This family of proteins contains several antioxidant enzymes such as the glutathione peroxidases, redox-regulating enzymes such as thioredoxin reductases, a methionine sulfoxide reductase, and others.
Aaron H, Rose, Peter R, Hoffmann
openaire   +2 more sources

Selenoproteins in mammalian spermatogenesis:role of the nuclear GPx4 [PDF]

open access: yes, 2011
The selenoprotein Phospholipid Hydroperoxide Glutathione Peroxidase (PHGPx/GPx4) is an enzyme unique among the various GPxs, because it is able to use protein thiols, beside glutathione, The GPx4 gene encodes for three isoforms having different ...
Maccari, Irene
core  

Atomic spectrometry update. Clinical and biological materials, foods and beverages [PDF]

open access: yes, 2013
This review discusses developments in elemental mass spectrometry, atomic absorption, emission and fluorescence, XRF and LIBS, as applied to the analysis of specimens of clinical interest, foods and beverages.
Day, Martin P.   +5 more
core   +2 more sources

Selenium and selenoprotein P1 levels are related to primary open-angle glaucoma [PDF]

open access: yesJournal of Medical Biochemistry, 2014
Background: Glaucoma is a highly prevalent eye disease related to optic nerve lesions and visual field defects. Primary Open-Angle Glaucoma (POAG) is a type of glaucoma that occurs frequently with unknown etiology.
Najafi Mohammad   +4 more
doaj  

Association of Selenoprotein and Selenium Pathway Genotypes with Risk of Colorectal Cancer and Interaction with Selenium Status

open access: yesNutrients, 2019
Selenoprotein genetic variations and suboptimal selenium (Se) levels may contribute to the risk of colorectal cancer (CRC) development. We examined the association between CRC risk and genotype for single nucleotide polymorphisms (SNPs) in selenoprotein ...
V. Fedirko   +50 more
semanticscholar   +1 more source

Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems

open access: yesThe Chemical Record, EarlyView.
Main nanocarriers employed to enhance the bioavailability and transport of organoselenium compounds. The image illustrates the key interaction forces that stabilize these organoselenium species in solution, enabling their application in drug delivery systems, catalysis, photoelectronic devices, and sensing technologies. In recent years, publications on
Romelly Eugenia Rojas Ramírez   +3 more
wiley   +1 more source

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