Results 81 to 90 of about 15,613 (163)

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Association of Selenoprotein P Levels With Proteinuria Severity in Newly Diagnosed Type 2 Diabetes Mellitus

Selçuk Tıp Dergisi
Objective: Diabetic nephropathy is one of the leading causes of chronic kidney disease and progression to end-stage renal failure. Identifying new biomarkers that correlate with nephropathy severity may improve risk stratification and clinical
Mustafa Turgut Yildizgoren, MEVLÜT HAKAN GÖKTEPE, Adem Ay, Gürkan Yarbas, Bilal Ilanbey, Cahit Uçar   +5 more
doaj   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Role of Selenoproteins in Redox Regulation of Signaling and the Antioxidant System: A Review

Antioxidants, 2020
Selenium is a vital trace element present as selenocysteine (Sec) in proteins that are, thus, known as selenoproteins. Humans have 25 selenoproteins, most of which are functionally characterized as oxidoreductases, where the Sec residue plays a catalytic
Ying Zhang, Yeon Jin Roh, Seong-Jeong Han, Iha Park, Hae Min Lee, Yong Sik Ok, Byung Cheon Lee, Seung-Rock Lee   +7 more
doaj   +1 more source

Chemical Kinetics of 2‐, 4‐, and 2,4‐Seleno‐Uracils at Low Temperatures: Tautomerizations and Rotamerizations on Inert Matrices

International Journal of Chemical Kinetics, Volume 58, Issue 10, Page 881-889, October 2026.
ABSTRACT In the interstellar medium, chemical reactions proceed under conditions vastly different to those on Earth; these include extremely low temperatures and densities and take place in the gas phase and on water–ice grains. Understanding the energetics and more importantly the kinetics of such reactions is of relevance to the consequences on how ...
Judith Wurmel, John M. Simmie
wiley   +1 more source

Radiotherapy‐Induced Side Effects: Epidemiology, Pathogenesis, Prevention and Treatments

MedComm, Volume 7, Issue 10, October 2026.
Radiotherapy for malignancies frequently injures the organs’ systems through oxidative stress, fibrosis, inflammation, and vascular damage. This review systematically maps the epidemiology, pathogenesis, and emerging therapies to propose a mechanism‑network‑targeted framework for integrated, personalized care in radiation oncology.
Xiaowen Ma, Xiaoxuan Zhang, Pujun Zhao, Jiaxin Yang, Zhihao Li, Xiaoyang Han, Yixuan Wang, Zhenzhen Cui, Nian Liu, Min Li   +9 more
wiley   +1 more source

Selenoprotein-Transgenic Chlamydomonas reinhardtii

, 2013
Selenium (Se) deficiency is associated with the occurrence of many diseases. However, excessive Se supplementation, especially with inorganic Se, can result in toxicity. Selenoproteins are the major forms of Se in vivo to exert its biological function.
Qintang Hou, Jing Tian, Shi Qiu, Zhangli Hu, Jiazuan Ni, Qiong Liu   +5 more
core   +1 more source

Antioxidant Responses to Dietary Supplementation With Non‐Enriched and Selenium‐Enriched Mushrooms and Selenized Yeast in Piglets

Molecular Nutrition &Food Research, Volume 70, Issue 19, 15 October 2026.
The findings highlight tissue‐specific responses to dietary selenium supplementation, with hepatic antioxidant modulation occurring without changes in plasma parameters, while selenium deposition patterns differed among tissues, emphasizing the complex relationship between selenium sources, metabolism, and antioxidant defense.
Diene France de de Souza, Gabriel Cipriano Rocha, Dairon Pérez Fuentes, Lucas Eduardo Oliveira Porto, Pedro Vitoriano Oliveira, Marliane de Cássia Soares da Silva, Maria Catarina Megumi Kasuya, Maiane de Paula Alves, Monique Renon Eller   +8 more
wiley   +1 more source

Synthesis and Cytotoxic Activity of 1,3‐Selenazole‐2‐Amine Derivatives With Computational ADMET Profiling

ChemistryOpen, Volume 15, Issue 10, October 2026.
Four novel 1,3‐selenazole‐2‐amine derivatives were synthesized and evaluated in HT‐29, MCF‐7, and L929 cell lines. Compound 4 showed the highest MCF‐7 cytotoxicity. Compound 3 displayed low L929 toxicity. In silico ADMET predicted favorable pharmacokinetic properties.
Gulay Dilek, Senem Akkoc
wiley   +1 more source

Iron deficiency in heart failure: Epidemiology, diagnostic criteria and treatment modalities

ESC Heart Failure, Volume 12, Issue 2, Page 723-726, April 2025.
Stephan von Haehling
wiley   +1 more source