Results 81 to 90 of about 14,403 (240)

Biological Effects of Selenium‐Containing Ionic Liquids: Cytotoxicity, Mercury Interaction, and Antiproliferative Activity in Glioblastoma Cells

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Selenium (Se) is an essential micronutrient that participates in redox regulation and cellular homeostasis. Selenium‐containing ionic liquids (ILsSe) have emerged as hybrid compounds combining the properties of organoselenium molecules with the tunable features of ionic liquids.
Guilherme Schmitt Rieder   +17 more
wiley   +1 more source

The Intrinsically Disordered Membrane Enzymes Selenoprotein S and Selenoprotein K [PDF]

open access: yesBiophysical Journal, 2015
Selenoproteins constitute a family of enzymes involved in the management and regulation of reactive oxygen species, signaling molecules that are also affiliated with molecular damage and disease. The family contains two intrinsically disordered membrane proteins: selenoprotein S (SelS) and selenoprotein K (SelK). Both of these bitopic membrane proteins
Jun, Liu   +2 more
openaire   +1 more source

Modifications of transfer RNA enhance selenoprotein biosynthesis [PDF]

open access: yes, 2022
Selenocysteine-containing proteins, selenoproteins, are generally favoured over cysteine-containing proteins in redox reactions and therefore of high interest due to their multiple bio-industrial applications.
University of Lethbridge. Faculty of Arts and Science   +1 more
core  

Safety of selenium exposure and limitations of selenoprotein maximization: Molecular and epidemiologic perspectives [PDF]

open access: yes, 2022
Recent evidence from laboratory and epidemiologic studies has shed a different light on selenium health effects and its recommended range of environmental exposure, compared with earlier research.
Filippini T.   +4 more
core   +1 more source

Selenium and selenoprotein P1 levels are related to primary open-angle glaucoma [PDF]

open access: yesJournal of Medical Biochemistry, 2014
Background: Glaucoma is a highly prevalent eye disease related to optic nerve lesions and visual field defects. Primary Open-Angle Glaucoma (POAG) is a type of glaucoma that occurs frequently with unknown etiology.
Najafi Mohammad   +4 more
doaj  

Liebig Review: Essential and Beneficial Elements in the Regulation of Cadmium Uptake and Tolerance in Crop Plants

open access: yesJournal of Plant Nutrition and Soil Science, EarlyView.
ABSTRACT Cadmium (Cd2+) contamination in agricultural soils has been reported to pose risks to crop productivity, food safety, and human health. This review synthesizes current knowledge on the mechanisms by which essential (S, Zn, Fe, Mg, K, Ca) and beneficial (Si, Se, rare earth elements) elements mitigate Cd2+ toxicity in plants.
Maria Manzoor, Karl Hermann Mühling
wiley   +1 more source

Response of rat selenoprotein P to selenium administration and fate of its selenium [PDF]

open access: yes, 1991
Selenoprotein P is a glycoprotein that contains greater than 60% of the selenium in rat plasma. Physiological experiments were undertaken to gain insight into selenoprotein P function.
T. Bellew   +3 more
core   +1 more source

Chemical Kinetics of 2‐, 4‐, and 2,4‐Seleno‐Uracils at Low Temperatures: Tautomerizations and Rotamerizations on Inert Matrices

open access: yesInternational Journal of Chemical Kinetics, EarlyView.
ABSTRACT In the interstellar medium, chemical reactions proceed under conditions vastly different to those on Earth; these include extremely low temperatures and densities and take place in the gas phase and on water–ice grains. Understanding the energetics and more importantly the kinetics of such reactions is of relevance to the consequences on how ...
Judith Wurmel, John M. Simmie
wiley   +1 more source

A Highly Powered Large Outcomes Randomised Controlled Trial Will Usually, but Not Always, Have Balanced Groups at Baseline

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Objective The importance of randomised trials for discerning an intervention's effect rests on randomisation's ability to create groups with (on average) equal hazards of future outcomes. The frequency with which this does not occur in well‐designed large trials with a high event rate was studied.
Hertzel C. Gerstein   +5 more
wiley   +1 more source

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

open access: yesThe FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna   +5 more
wiley   +1 more source

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