Results 61 to 70 of about 14,403 (240)

Hypoxia reduces and redirects selenoprotein biosynthesis [PDF]

open access: yes, 2014
Available open access thanks to the RSC Gold for Gold initiative. Shared according to the terms set out in the CC licence.Selenium deficiency constitutes a risk factor for the incidence and negative course of severe diseases including sepsis, stroke ...
Stoedter, Mette   +6 more
core   +1 more source

Inhibition of selenoprotein synthesis by Zika virus may contribute to congenital Zika syndrome and microcephaly by mimicking SELENOP knockout and the genetic disease PCCA

open access: yesBBA Advances, 2021
Selenium status plays a major role in health impacts of various RNA viruses. We previously reported potential antisense interactions between viral mRNAs and host mRNAs encoding isoforms of the antioxidant selenoprotein thioredoxin reductase (TXNRD). Here,
Gabrielle P. Dailey   +3 more
doaj   +1 more source

Bifunctional injectable selenium‐containing polyurethane hydrogels for periodontal regeneration through endoplasmic reticulum stress modulation

open access: yesBMEMat, EarlyView.
Graphical illustration of the synthesis, biological functions and mechanisms of bifunctional injectable selenium‐containing polyurethane hydrogels. Abstract Periodontitis causes progressive destruction of both periodontal soft and hard tissues, leading to tooth loss and functional impairment.
Mingchu Zhao   +8 more
wiley   +1 more source

Selenium influences tissue levels of selenoprotein W in sheep. [PDF]

open access: yes, 2010
[[abstract]]Because selenium increases the levels of other selenoproteins, the influence of this element on selenoprotein W was examined in wether sheep fed either a low selenium diet (0.02 mg/kg) or the same diet supplemented with 3 mg selenium as ...
Yeh, J. Y.;Gu, Q.;Beilstein, M. A.;Forsberg, N. E.;Whanger, P. D
core   +1 more source

LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma

open access: yesEMBO Molecular Medicine, 2023
Ferroptosis has emerged as an attractive strategy in cancer therapy. Understanding the operational networks regulating ferroptosis may unravel vulnerabilities that could be harnessed for therapeutic benefit. Using CRISPR‐activation screens in ferroptosis
Hamed Alborzinia   +32 more
doaj   +1 more source

Heat stress in spermatogenesis: a redox‐dependent decision network linking ROS, autophagy, and regulated cell death

open access: yesBiological Reviews, EarlyView.
ABSTRACT Heat stress (HS) is an increasing threat to male reproductive health, disrupting spermatogenesis through complex and interdependent cellular responses within the seminiferous epithelium. Although excessive reactive oxygen species (ROS) production is a hallmark of HS, ROS also act as central regulators of cell fate decisions beyond their role ...
Ribrio Ivan Tavares Pereira Batista
wiley   +1 more source

Micronutrient Status in Children Suffering From Anorexia Nervosa: A Cohort of 349 Patients in a Referral Center for Eating Disorders

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a serious illness in which more than half of all deaths are due to malnutrition. Critically low energy and protein intake are known causes of massive weight loss, whereas micronutrient deficiencies due to a low‐calorie food pattern remain poorly characterized in children with AN. Micronutrient deficiencies in
Zenaida Iordan   +6 more
wiley   +1 more source

Eukaryotic selenoproteins and selenoproteomes

open access: yesBiochimica et Biophysica Acta (BBA) - General Subjects, 2009
Selenium is an essential trace element for which both beneficial and toxic effects in human health have been described. It is now clear that the importance of having adequate amounts of this micronutrient in the diet is primarily due to the fact that selenium is required for biosynthesis of selenocysteine, the twenty first naturally occurring amino ...
Lobanov, Alexey V.   +2 more
openaire   +3 more sources

SEPP1 (selenoprotein P, plasma, 1) [PDF]

open access: yes, 2011
Review on SEPP1 (selenoprotein P, plasma, 1), with data on DNA, on the protein encoded, and where the gene is ...
Jablonska, E   +3 more
core   +1 more source

Knockdown of selenocysteine-specific elongation factor in Amblyomma maculatum alters the pathogen burden of Rickettsia parkeri with epigenetic control by the Sin3 histone deacetylase corepressor complex.

open access: yesPLoS ONE, 2013
Selenocysteine is the 21st naturally-occurring amino acid. Selenoproteins have diverse functions and many remain uncharacterized, but they are typically associated with antioxidant activity.
Steven W Adamson   +4 more
doaj   +1 more source

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