Results 51 to 60 of about 27,808 (261)

Selenoproteins and their emerging roles in signaling pathways

open access: yesRegulatory Mechanisms in Biosystems, 2020
The functional activity of selenoproteins has a wide range of effects on complex pathogenetic processes, including teratogenesis, immuno-inflammatory, neurodegenerative.
N. V. Stanishevska
doaj   +1 more source

Roles of Selenoproteins in Brain Function and the Potential Mechanism of Selenium in Alzheimer’s Disease

open access: yesFrontiers in Neuroscience, 2021
Selenium (Se) and its compounds have been reported to have great potential in the prevention and treatment of Alzheimer’s disease (AD). However, little is known about the functional mechanism of Se in these processes, limiting its further clinical ...
Zhong-Hao Zhang   +4 more
doaj   +1 more source

Selenium in Prostate Cancer: Prevention, Progression, and Treatment

open access: yesPharmaceuticals, 2023
Selenium, a trace mineral with various biological functions, has become a focal point in prostate cancer research. This review aims to present a comprehensive overview of selenium’s involvement in prostate cancer, covering its impact on prevention ...
Jinjiang Jiang   +3 more
doaj   +1 more source

Human Disorders Affecting the Selenocysteine Incorporation Pathway Cause Systemic Selenoprotein Deficiency

open access: yesAntioxidants and Redox Signaling, 2020
Significance: Generalized selenoprotein deficiency has been associated with mutations in SECISBP2, SEPSECS, and TRU-TCA1-1, 3 factors that are crucial for incorporation of the amino acid selenocysteine (Sec) into at least 25 human selenoproteins ...
E. Schoenmakers, K. Chatterjee
semanticscholar   +1 more source

Mercury and selenium binding biomolecules in terrestrial mammals (Cervus elaphus and Sus scrofa) from a mercury exposed area [PDF]

open access: yes, 2017
Acknowledgements The authors are grateful to Junta de Comunidades de Castilla-La Mancha (PCC-05-004-2, PAI06-0094, PCI-08-0096, PEII09-0032-5329) and the Ministerio de Economía y Competitividad (CTQ2013-48411-P) for financial support. M.J.
Fariñas, N. Rodríguez   +5 more
core   +1 more source

Hydroxy-Selenomethionine Improves the Selenium Status and Helps to Maintain Broiler Performances under a High Stocking Density and Heat Stress Conditions through a Better Redox and Immune Response

open access: yesAntioxidants, 2021
This study has determined whether hydroxy-selenomethionine (OH-SeMet) exerts a better protective action on broilers against environmental stress than sodium selenite (SS) or seleno-yeast (SY).
Hua Sun   +6 more
doaj   +1 more source

Selenium Status in Diet Affects Nephrotoxicity Induced by Cisplatin in Mice

open access: yesAntioxidants, 2022
Cisplatin is one of the most active chemotherapy drugs to treat solid tumors. However, it also causes various side effects, especially nephrotoxicity, in which oxidative stress plays critical roles.
Shuang Liu   +4 more
doaj   +1 more source

Analysis of Selenoprotein Expression in Response to Dietary Selenium Deficiency During Pregnancy Indicates Tissue Specific Differential Expression in Mothers and Sex Specific Changes in the Fetus and Offspring

open access: yesInternational Journal of Molecular Sciences, 2020
The human selenoproteome is comprised of ~25 genes, which incorporate selenium, in the form of selenocysteine, into their structure. Since it is well known that selenium is important to maternal health and foetal development during pregnancy, this study ...
Pierre Hofstee, J. Cuffe, A. Perkins
semanticscholar   +1 more source

Impact of treatment planning target volumen (PTV) size on radiation induced diarrhoea following selenium supplementation in gynecologic radiation oncology - a subgroup analysis of a multicenter, phase III trial [PDF]

open access: yes, 2013
Background: In a previous analysis (Int J Radiat Oncol Biol Phys 70:828-835,2010), we assessed whether an adjuvant supplementation with selenium (Se) improves Se status and reduces the radiation-induced side-effects of patients treated by adjuvant ...
Adamietz, Irenäus A.   +14 more
core   +1 more source

Role of microRNA-7 and selenoprotein P in hepatocellular carcinoma

open access: yesTumor Biology, 2017
There is an obvious need to diagnose hepatocellular carcinoma using novel non-invasive and sensitive biomarkers. In this regard, the aim of this study was to evaluate and correlate both relative quantification of microRNA-7 using quantitative real time ...
Marwa Tarek   +5 more
doaj   +1 more source

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