Results 91 to 100 of about 17,575 (209)

Selenoproteins and their emerging roles in signaling pathways

open access: yesRegulatory Mechanisms in Biosystems, 2020
The functional activity of selenoproteins has a wide range of effects on complex pathogenetic processes, including teratogenesis, immuno-inflammatory, neurodegenerative.
N. V. Stanishevska
doaj   +1 more source

Advances in large DNA fragment assembly for microbial cell factory engineering

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang   +5 more
wiley   +1 more source

Selenoprotein-P Deficiency Predicts Cardiovascular Disease and Death [PDF]

open access: yesNutrients, 2019
Selenoprotein-P (SELENOP) is the main carrier of selenium to target organs and reduces tissue oxidative stress both directly and by delivering selenium to protective selenoproteins. We tested if the plasma concentration of SELENOP predicts cardiovascular morbidity and mortality in the primary preventive setting.
Lutz Schomburg   +4 more
openaire   +2 more sources

Selenoprotein N is dynamically expressed during mouse development and detected early in muscle precursors [PDF]

open access: yes, 2009
International audienceBACKGROUND: In humans, mutations in the SEPN1 gene, encoding selenoprotein N (SelN), are involved in early onset recessive neuromuscular disorders, referred to as SEPN1-related-myopathies. The mechanisms behind these pathologies are
Alain Krol   +8 more
core   +5 more sources

From Assessment to Optimization: A Comprehensive Review of the Mutton Quality Evaluation Index, Factors, and Improvement Strategies

open access: yesFood Frontiers, Volume 7, Issue 3, May 2026.
This graphical abstract summarizes the comprehensive framework of mutton quality, including evaluation indices, influencing factors, and improvement strategies. Meat quality is systematically assessed through multiple dimensions, including flavor, color, pH, tenderness, water‐holding capacity, intramuscular fat, and nutritional composition.
Man‐yu Liu   +6 more
wiley   +1 more source

キイロショウジョウバエ由来のチオレドキシン還元酵素のC未端テトラペプチド配列は、ヒト肺由来のチオレドキシン還元酵素では酸化還元活性を示さない [PDF]

open access: yes, 2007
The isozymes of mammalian thioredoxin reductase (TrxR) contain the penultimate selenocysteineresidue (SeCys) in the redox-active C-terminal tetrapeptide, -Gly-Cys-SeCys-Gly (end). Amutant form of the mammalian enzyme TrxR-X498C in which SeCys is replaced
Inagaki, Kenji   +3 more
core  

A possible role for selenoprotein glutathione peroxidase (GPx1) and thioredoxin reductases (TrxR1) in thyroid cancer. Our experience in thyroid surgery [PDF]

open access: yes, 2018
Background: Oxidative stress is responsible for some alterations in the chemical structure and, consequently, in the function of proteins, lipids, and DNA.
DE LUCA, Alessandro   +6 more
core   +2 more sources

Histone Deacetylase 9 Gene Deletion Ameliorates Aging‐Related Adipose Tissue Senescence and Mitochondrial Dysfunction in Mice

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Cellular senescence and mitochondrial dysfunction disrupt adipose tissue homeostasis during aging, but mechanisms remain unclear. HDAC9 expression increases with age in mouse adipose tissue and Hdac9 knockout mice showed reduced fat mass, senescence markers, and enhanced mitochondrial gene expression, respiration, and thiosulfate sulfurtransferase (Tst)
Brandee Goo   +15 more
wiley   +1 more source

Complete Genome Sequence of the Citrobacter freundii Type Strain. [PDF]

open access: yes, 2020
Citrobacter freundii is a species of facultative anaerobic Gram-negative bacteria of the family Enterobacteriaceae The complete genome is composed of a single chromosomal circle of 4,957,773 bp with a G+C content of 52%
Booth, Benjamin W   +5 more
core  

Spaceflight modulates gene expression in the whole blood of astronauts [PDF]

open access: yes, 2016
Astronauts are exposed to a unique combination of stressors during spaceflight, which leads to alterations in their physiology and potentially increases their susceptibility to disease, including infectious diseases.
Barrila, Jennifer   +7 more
core   +2 more sources

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