Results 101 to 110 of about 17,575 (209)

An atlas of plant selenium metabolism

New Phytologist, Volume 250, Issue 4, Page 2041-2060, May 2026.
Summary Selenium (Se) is not only a rare and toxic element but also an essential micronutrient for humans and animals that is often in short supply. Terrestrial plants do not require Se, but it can have growth‐promoting or negative effects, depending on the exposure level.
Jeroen van der Woude, Mark G. M. Aarts, Michela Schiavon, Antony van der Ent   +3 more
wiley   +1 more source

Bio-efficacy of hydroxy-selenomethionine as a selenium supplement in pregnant dairy heifers and on the selenium status of their calves [PDF]

, 2019
This study aimed to determine the effects of supplementing pregnant heifers with the organic selenium source 2-hydroxy-4-methylselenobutanoic acid (HMSeBA) during last eight weeks of pregnancy on dam and calf Se status. A total of 42 in-calf heifers were
Anderson, Apperson, Briens, Briens, Burk, Burk, C. Rymer, Calamari, Colakoglu, Cortinhas, D.T. Juniper, Gong, Gunter, Guyot, Hill, Howard, Jlali, Jlali, Juniper, Juniper, Juniper, Kincaid, Labunskyy, M. Briens, Martín-Venegas, McDonald, Meyer, Pehrson, Peters, Phipps, Rowntree, Salman, Seyedali, Slavik, Sneddon, Stockdale, Stowe, Sun, Sun, Sunde, Surai, Surai, Surai, Swecker, Touat-Hamici, Underwood, Vacchina, Vacchina, Wolffram   +48 more
core   +1 more source

Diagnostic significance of the newest biomarkers of steatosis progression in patients with stable coronary heart disease, combined with nonalcoholic fatty liver disease

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
The purpose was to determine the diagnostic value of selenoprotein P and M30 fragments of cytokeratin 18 in conjunction with proinflammatory cytokines for early diagnosis and progression of non-alcoholic fatty liver disease (NAFLD) in patients with ...
I. I. Vakalyuk, N. G. Virstyuk
doaj   +1 more source

Fetuin‐b Mediates Lipid Overload‐Induced Hepatic Lipid Accumulation in Large Yellow Croaker (Larimichthys crocea)

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Schematic of the mechanism of fetuin‐b mediated high‐fat diet‐induced hepatic steatosis in Larimichthys crocea. Lipid overload triggers C/EBPα‐mediated fetuin‐b upregulation. Fetuin‐b drives hepatic lipid accumulation by reprogramming lipid metabolism and inhibiting Plin2 ubiquitination to stabilize lipid droplets, identifying it as a potential ...
Yanan Shen, Qiuchi Chen, Zengqi Zhao, Qiang Chen, Yuhang Tang, Fan Chen, Tingting Hao, Jianlong Du, Qinghui Ai   +8 more
wiley   +1 more source

Selenoprotein P gene r25191g/a polymorphism and quantification of selenoprotein P mRNA level in patients with Kashin-Beck disease [PDF]

British Journal of Nutrition, 2010
Kashin-Beck disease (KBD) is an endemic and deformable osteoarthrosis. Epidemiological study has revealed that lower Se level is the principal environmental factor in the pathogenesis of KBD. Selenoprotein P (SEPP1) is a special selenoprotein, which is the primary form of Se in vivo.
Wenyan, Sun, Xin, Wang, Xiuzhen, Zou, Ruixia, Song, Xiaohong, Du, Jun, Hu, Yongmin, Xiong   +6 more
openaire   +2 more sources

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, Volume 36, Issue 30, 13 April 2026.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Friend or foe? The current epidemiologic evidence on selenium and human cancer risk. [PDF]

, 2013
Scientific opinion on the relationship between selenium and the risk of cancer has undergone radical change over the years, with selenium first viewed as a possible carcinogen in the 1940s then as a possible cancer preventive agent in the 1960s-2000s ...
Ammar E M, Bhattacharya A, Bjelakovic G, Blot W J, Buntzel J, CARLOTTA MALAGOLI, CATHERINE M. CRESPI, CINZIA DEL GIOVANE, Clayton C C, Cortes-Jofre M, Csallany A S, Dalkin B W, Dennert G, Dreno B, Duffield-Lillico A J, Hafeman D G, Hartman T J, Hercberg S, Hunter D J, Karp D D, Kim Y W, Kok F J, Krogh V, Levander OA., Li H, Li W, Lillico A, MARCO VINCETI, Marshall J R, Nelson A A, Ovaskainen M L, Peleg I, Ravn-Haren G, Rees K, Reid M E, Rothman K J, Salbe A D, Salbe A D, Salonen J T, Shamberger R J, Sunde RA., Swanson C A, Trougakos IP., van den Brandt P A, Vinceti M, Vinceti M, VITTORIO KROGH, Zheng S, Zhuo H   +48 more
core   +1 more source

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

Advanced Science, Volume 13, Issue 22, 17 April 2026.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang, Yuchen Wang, Binbin Li, Xin Li, Chenyu Liu, Yanhao Chen, Cheng Tian, Dongmei Wang, Xiaosong Gu, Chunping Jiang, Yuda Wei, Qiurong Ding   +11 more
wiley   +1 more source

Selenoprotein P mRNA expression in human hepatic tissues

World Journal of Gastroenterology, 2007
To investigate the expression of selenoprotein P mRNA (SePmRNA) in tissues of normal liver, liver cirrhosis and hepatocellular carcinoma (HCC), and its relationship with HCC occurrence and development.The expression of SePmRNA in tissues of normal liver, liver cirrhosis and HCC were detected by in situ hybridization using a cDNA probe.The enzyme ...
Chun-Li, Li, Ke-Jun, Nan, Tao, Tian, Chen-Guang, Sui, Yan-Fang, Liu   +4 more
openaire   +2 more sources

Congenital muscle disorders with cores: the ryanodine receptor calcium channel paradigm [PDF]

, 2008
Dysregulation of calcium signals because of defects of the skeletal muscle sarcoplasmic reticulum calcium release channel (ryanodine receptor; RyR1) is causative of several congenital muscle disorders including malignant hyperthermia (MH; MIM #145600 ...
Jungbluth, Heinz, Muntoni, Francesco, Treves, Susan, Zorzato, Francesco   +3 more
core   +1 more source