Results 81 to 90 of about 10,363 (168)

Cloning and characterization of the human selenoprotein P promoter. Response of selenoprotein P expression to cytokines in liver cells.

open access: yesThe Journal of biological chemistry, 1997
We isolated an 18-kilobase (kb) genomic selenoprotein P clone from a human placenta library and cloned, sequenced, and characterized the 5'-flanking region of the human selenoprotein P gene. Sequence analysis revealed an intron between base pairs (bp) -13 and -14 upstream of the ATG codon and another one between bp 534 and 535 of the coding region. The
I, Dreher, T C, Jakobs, J, Köhrle
openaire   +2 more sources

Ccdc152 is not necessary for male fertility, but contributes to maintaining sperm morphology

open access: yesThe Journal of Reproduction and Development
Selenoprotein P (SeP) is synthesized in the liver and plays a vital role in maintaining selenium homeostasis via transport throughout the body. Previous studies have shown that SeP-deficient mice have severely reduced expression of selenoproteins ...
Ryua HARIMA   +8 more
doaj   +1 more source

Selenoprotein P status correlates to cancer-specific mortality in renal cancer patients.

open access: yesPLoS ONE, 2012
Selenium (Se) is an essential trace element for selenoprotein biosynthesis. Selenoproteins have been implicated in cancer risk and tumor development. Selenoprotein P (SePP) serves as the major Se transport protein in blood and as reliable biomarker of Se
Hellmuth A Meyer   +7 more
doaj   +1 more source

Comparative Effects of Origanum onites L. Extract and Carvacrol on the Metabolic Syndrome and Hepatic/Pancreatic Inflammatory Markers in Rats

open access: yesPolish Journal of Food and Nutrition Sciences
This study investigated the effects of an Origanum onites L. extract, carvacrol, and metformin on the metabolic syndrome (MetS) induced by a high-fat, high-fructose diet (HFFD) in rats.
Kubra Öztürk   +4 more
doaj   +1 more source

Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation independent of Nrf2. [PDF]

open access: yesCommun Biol, 2023
Ye X   +7 more
europepmc   +1 more source

An efficient selenium transport pathway of selenoprotein P utilizing a high-affinity ApoER2 receptor variant and being independent of selenocysteine lyase. [PDF]

open access: yesJ Biol Chem, 2023
Mizuno A   +14 more
europepmc   +1 more source

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