Results 61 to 70 of about 10,363 (168)

Chemical Kinetics of 2‐, 4‐, and 2,4‐Seleno‐Uracils at Low Temperatures: Tautomerizations and Rotamerizations on Inert Matrices

International Journal of Chemical Kinetics, EarlyView.
ABSTRACT In the interstellar medium, chemical reactions proceed under conditions vastly different to those on Earth; these include extremely low temperatures and densities and take place in the gas phase and on water–ice grains. Understanding the energetics and more importantly the kinetics of such reactions is of relevance to the consequences on how ...
Judith Wurmel, John M. Simmie
wiley   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Predictive Value of Selenoprotein P in Newly Diagnosed Type 2 Diabetes: A Diagnostic Accuracy Study

Endocrinology Research and Practice
Objective: To investigate levels of selenoprotein P (SeP), a liver-derived hepatokine, in patients with newly diagnosed type 2 diabetes mellitus (T2DM) compared with healthy controls and to evaluate its relationship with metabolic indicators. Methods:
Gürkan Yarbaş, Cahit Uçar, Filiz Alkan Baylan, Mustafa Turgut Yıldızgören   +3 more
doaj   +3 more sources

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Selenoprotein P is the major selenium transport protein in mouse milk. [PDF]

PLoS ONE, 2014
Selenium is transferred from the mouse dam to its neonate via milk. Milk contains selenium in selenoprotein form as selenoprotein P (Sepp1) and glutathione peroxidase-3 (Gpx3) as well as in non-specific protein form as selenomethionine.
Kristina E Hill, Amy K Motley, Virginia P Winfrey, Raymond F Burk   +3 more
doaj   +1 more source

Oxidative and Antioxidant Systems in Ferroptosis of Cancer: Mechanisms, Regulations, and Therapeutic Targeting

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K, Pritam Kumar Roy, Maniklal Shee, Budhaditya Mukherjee, Aoife Ward Gahlawat, Mahitosh Mandal   +5 more
wiley   +1 more source

Advances in large DNA fragment assembly for microbial cell factory engineering

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang, Wenqian Liu, Dongyuan Cheng, Jiazhang Lian, Xian Fu, Yue Shen   +5 more
wiley   +1 more source

Selenoproteins and their emerging roles in signaling pathways

Regulatory Mechanisms in Biosystems, 2020
The functional activity of selenoproteins has a wide range of effects on complex pathogenetic processes, including teratogenesis, immuno-inflammatory, neurodegenerative.
N. V. Stanishevska
doaj   +1 more source

Transcriptional Regulation of HSP60, HSP70, and HSP90 in Response to Selenium Nanoparticles and Sodium Selenite in Periparturient Cloned Saanen Goats and Their Offspring

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Selenium nanoparticles (SeNPs) outperform sodium selenite in raising serum selenium levels and suppressing HSP60, HSP70, and HSP90 transcription in periparturient goats and their offspring, indicating reduced cellular stress regardless of cloning status.
Gholam‐Ali Kojouri, Hossein Hassanpour, Ahmad Yousefi   +2 more
wiley   +1 more source

A Highly Powered Large Outcomes Randomised Controlled Trial Will Usually, but Not Always, Have Balanced Groups at Baseline

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8595-8601, September 2026.
ABSTRACT Objective The importance of randomised trials for discerning an intervention's effect rests on randomisation's ability to create groups with (on average) equal hazards of future outcomes. The frequency with which this does not occur in well‐designed large trials with a high event rate was studied.
Hertzel C. Gerstein, Zayeeda Labiba, Sibylle Hess, Kamel Mohammedi, Yueci Zhou, Shun Fu Lee   +5 more
wiley   +1 more source