Results 61 to 70 of about 17,575 (209)
Regulation of Redox Signaling by Selenoproteins [PDF]
, 2010 The unique chemistry of oxygen has been both a resource and threat for life on Earth for at least the last 2.4 billion years. Reduction of oxygen to water allows extraction of more metabolic energy from organic fuels than is possible through anaerobic ...
Wayne Chris Hawkes, Zeynep Alkan
core +1 more source
Selenium and selenoprotein P1 levels are related to primary open-angle glaucoma [PDF]
Journal of Medical Biochemistry, 2014 Background: Glaucoma is a highly prevalent eye disease related to optic nerve lesions and visual field defects. Primary Open-Angle Glaucoma (POAG) is a type of glaucoma that occurs frequently with unknown etiology.
Najafi Mohammad +4 more
doaj
Advanced Science, EarlyView.We present a mechanochemical, radical‐mediated hydroselenation of alkenes under ambient conditions. This method modularly generates alkyl selenyl radicals from elemental selenium and alkyl (pseudo)halides, utilizing PhSiH3 and H2O as hydrogen atom donors, with the water likely originating from the air and/or trace water present in the reagents ...
Xiaochun He +8 more
wiley +1 more source
Selenoprotein P—Expression, functions, and roles in mammals [PDF]
Biochimica et Biophysica Acta (BBA) - General Subjects, 2009 Selenoprotein P (Sepp1) is a secreted protein that is made up of 2 domains. The larger N-terminal domain contains 1 selenocysteine residue in a redox motif and the smaller C-terminal domain contains the other 9 selenocysteines. Sepp1 isoforms of varying lengths occur but quantitation of them has not been achieved.
Raymond F, Burk, Kristina E, Hill
openaire +2 more sources
SECISearch3 and Seblastian: new tools for prediction of SECIS elements and selenoproteins [PDF]
, 2014 Selenoproteins are proteins containing an uncommon amino acid selenocysteine (Sec). Sec is inserted by a specific translational machinery that recognizes a stem-loop structure, the SECIS element, at the 3′ UTR of selenoprotein genes and recodes a UGA ...
Gladyshev, Vadim N. +3 more
core +1 more source
Antioxidants, 2019 Selenium deficiency has been linked to anemia of inflammation, which is mediated by hepcidin. However, there are few studies providing evidence of the role of hepcidin in this relationship.
Doreen Yvonne Larvie +3 more
doaj +1 more source
Advanced Science, EarlyView.Inspired by natural amino acid polymer‐melanin systems, this study strategically incorporated tellurocysteine to develop advanced radiation‐shielding materials. This approach transformed the primary interaction mechanism between melanin‐based materials and incident photons from Compton scattering to the photoelectric effect. Tellurocysteine‐polymerized
Wei Chen +6 more
wiley +1 more source
UGA codon position-dependent incorporation of selenocysteine into mammalian selenoproteins [PDF]
, 2013 It is thought that the SelenoCysteine Insertion Sequence (SECIS) element and UGA codon are sufficient for selenocysteine (Sec) insertion. However, we found that UGA supported Sec insertion only at its natural position or in its close proximity in ...
Gladyshev, Vadim N. +3 more
core +1 more source
Journal of Translational Medicine, 2023 Introduction Low serum selenium and altered tumour RNA expression of certain selenoproteins are associated with a poor breast cancer prognosis. Selenoprotein expression stringently depends on selenium availability, hence circulating selenium may interact
Kamil Demircan +11 more
doaj +1 more source
Biomedicines, 2021 A higher selenium (Se) status has been shown to be associated with lower risk for colorectal cancer (CRC), but the importance of Se in survival after CRC diagnosis is not well studied. The associations of prediagnostic circulating Se status (as indicated
Jacqueline Roshelli Baker +31 more
doaj +1 more source