Selenium and vascular health [PDF]
, 2011 Peer reviewedPublisher ...
Sneddon, Alan A.
core +1 more source
Selenium-Binding Protein 1 Indicates Myocardial Stress and Risk for Adverse Outcome in Cardiac Surgery [PDF]
, 2019 Selenium-binding protein 1 (SELENBP1) is an intracellular protein that has been detected in the circulation in response to myocardial infarction. Hypoxia and cardiac surgery affect selenoprotein expression and selenium (Se) status.
Kühn, Eike C. +8 more
core +1 more source
Evolution of selenoproteins in the metazoan
BMC Genomics, 2012 Background The selenocysteine (Sec) containing proteins, selenoproteins, are an important group of proteins present throughout all 3 kingdoms of life.
Jiang Liang, Ni Jiazuan, Liu Qiong
doaj +1 more source
Selenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression
BMC Immunology, 2009 Background Selenium, a micronutrient whose deficiency in diet causes immune dysfunction and inflammatory disorders, is thought to exert its physiological effects mostly in the form of selenium-containing proteins (selenoproteins).
Gladyshev Vadim N +8 more
doaj +1 more source
Associations and interactions between variants in selenoprotein genes, selenoprotein levels and the development of abdominal aortic aneurysm, peripheral arterial disease, and heart failure. [PDF]
PLoS ONE, 2018 BACKGROUND:Little is known on the role of selenoprotein genes in cardiovascular disease. This study examines the associations of the SEPP1, SELENOS, TXNRD1, TXNRD2, GPX4, and SOD2 polymorphisms and selenoprotein P (SeP) and thioredoxin concentrations ...
Ewa Strauss +3 more
doaj +1 more source
Protein modification and maintenance systems as biomarkers of ageing [PDF]
, 2015 Changes in the abundance and post-translational modification of proteins and accumulation of some covalently modified proteins have been proposed to represent hallmarks of biological ageing.
Friguet, Bertrand +7 more
core +4 more sources
Characterization of the aerosol produced by infrared femtosecond laser ablation of polyacrylamide gels for the sensitive inductively coupled plasma mass spectrometry detection of selenoproteins [PDF]
, 2009 A 2D high repetition rate femtosecondlaserablation strategy (2-mm wide lane) previously developed for the detection of selenoproteins in gel electrophoresis by inductively coupled plasma mass spectrometry was found to increase signal sensitivity by a ...
Alexis, Joël +7 more
core +3 more sources
Nature Communications, 2017 Selenoprotein P is secreted by the liver and when present in excess it promotes development of type 2 diabetes. Here the authors develop neutralizing antibodies to target human and mouse selenoprotein P, and show that they improve insulin secretion and ...
Yuichiro Mita +15 more
doaj +1 more source
Germline genetic variation in prostate susceptibility does not predict outcomes in the chemoprevention trials PCPT and SELECT [PDF]
, 2020 Background The development of prostate cancer can be influenced by genetic and environmental factors. Numerous germline SNPs influence prostate cancer susceptibility.
Ahmed, M +7 more
core +2 more sources
Altered hippocampus synaptic function in selenoprotein P deficient mice
Molecular Neurodegeneration, 2006 Selenium is an essential micronutrient that function through selenoproteins. Selenium deficiency results in lower concentrations of selenium and selenoproteins.
Peters Melinda M +3 more
doaj +1 more source