Results 51 to 60 of about 10,363 (168)

Uptake and Utilization of Selenium from Selenoprotein P [PDF]

open access: yesBiological Trace Element Research, 2017
Selenoprotein P (SELENOP) is a serum glycoprotein that is required for proper selenium distribution in mammals, particularly in supplying selenium to the brain and testes. As the sole mechanism for providing essential selenium to developing spermatozoa, SELENOP metabolism is central to male fertility in all mammals.
Sumangala Shetty   +2 more
openaire   +2 more sources

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai   +2 more
wiley   +1 more source

Matched analysis of circulating selenium with the breast cancer selenotranscriptome: a multicentre prospective study

open access: yesJournal of Translational Medicine, 2023
Introduction Low serum selenium and altered tumour RNA expression of certain selenoproteins are associated with a poor breast cancer prognosis. Selenoprotein expression stringently depends on selenium availability, hence circulating selenium may interact
Kamil Demircan   +11 more
doaj   +1 more source

Prediagnostic Blood Selenium Status and Mortality among Patients with Colorectal Cancer in Western European Populations

open access: yesBiomedicines, 2021
A higher selenium (Se) status has been shown to be associated with lower risk for colorectal cancer (CRC), but the importance of Se in survival after CRC diagnosis is not well studied. The associations of prediagnostic circulating Se status (as indicated
Jacqueline Roshelli Baker   +31 more
doaj   +1 more source

Nucleophile Exchange Mechanistic Paths in Chalcogenolate‐Dichalcogenide Systems: Insight From Computational Chemistry

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
The change of the chalcogen! This computational study explores trends in Group 16 nucleophile exchange model reactions, providing mechanistic insight in gas phase and in solvent as well as biological implications, which can guide the design of improved biomimetic catalysts.
Alessandro Rubbi   +2 more
wiley   +1 more source

Selenoprotein P is the essential selenium transporter for bones

open access: yesMetallomics, 2014
Hepatic selenoprotein P transports Se to bones and constitutes an essential factor for bone mineral homeostasis.
Nicole, Pietschmann   +6 more
openaire   +3 more sources

Modern concept of biological identification of selenoproteins

open access: yesRegulatory Mechanisms in Biosystems, 2018
Humans possess 25 selenoproteins, approximately half of which are enzymes (selenoenzymes) required for preventing, regulating, or reversing oxidative damage, while others participate in providing calcium metabolism, thyroid hormone maintenance, protein ...
N. V. Stanishevska
doaj   +1 more source

Pancreatic atrophy caused by dietary selenium deficiency induces hypoinsulinemic hyperglycemia via global down-regulation of selenoprotein encoding genes in broilers. [PDF]

open access: yesPLoS ONE, 2017
This study was envisaged to comprehensively profile genes in selected tissues along with a few biochemical indicators and integrate resulting information with dietary selenium (Se) deficiency symptoms in broilers.
Jingyang Xu   +8 more
doaj   +1 more source

Biological Effects of Selenium‐Containing Ionic Liquids: Cytotoxicity, Mercury Interaction, and Antiproliferative Activity in Glioblastoma Cells

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Selenium (Se) is an essential micronutrient that participates in redox regulation and cellular homeostasis. Selenium‐containing ionic liquids (ILsSe) have emerged as hybrid compounds combining the properties of organoselenium molecules with the tunable features of ionic liquids.
Guilherme Schmitt Rieder   +17 more
wiley   +1 more source

Selenoprotein P gene r25191g/a polymorphism and quantification of selenoprotein P mRNA level in patients with Kashin-Beck disease [PDF]

open access: yesBritish Journal of Nutrition, 2010
Kashin-Beck disease (KBD) is an endemic and deformable osteoarthrosis. Epidemiological study has revealed that lower Se level is the principal environmental factor in the pathogenesis of KBD. Selenoprotein P (SEPP1) is a special selenoprotein, which is the primary form of Se in vivo.
Wenyan, Sun   +6 more
openaire   +2 more sources

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