Results 31 to 40 of about 24,108,879 (155)

Selenium in biology: Facts and medical perspectives [PDF]

, 2000
Several decades after the discovery of setenium as an essential trace element in vertebrates approximately 20 eukaryotic and more than 15 prokaryotic selenoproteins containing the 21(st) proteinogenic amino acid, selenocysteine, have been identified ...
Flohé, Leopold, Gärtner, Roland, Köhrle, Josef, Brigelius-Flohé, Regina, Böck, August, Meyer, Ortwin, Regina Brigelius-Flohé, Josef Köhrle, Ortwin Meyer, August Böck, Leopold Flohé, Roland Gärtner   +11 more
core   +2 more sources

A randomized trial of selenium supplementation and risk of type-2 diabetes, as assessed by plasma adiponectin [PDF]

, 2012
Background: Evidence that selenium affects the risk of type-2 diabetes is conflicting, with observational studies and a few randomized trials showing both lower and higher risk linked to the level of selenium intake and status. We investigated the effect
Steinbrenner, Holger, Eliseo Guallar, Roberto Pastor-Barriuso, Stranges, S, Steinbrenner Holger, Blundell-Pound, G, Eliseo Guallar (27363), Gabrielle Blundell-Pound, Pastor-Barriuso, R, Margaret P Rayman, Pastor-Barriuso, Roberto, Blundell-Pound Gabrielle, Rayman, Margaret, Blundell-Pound, Gabrielle, Holger Steinbrenner, Stranges, Saverio, Roberto Pastor-Barriuso (62759), Gabrielle Blundell-Pound (135140), Stranges Saverio, Guallar, E, Guallar, Eliseo, Saverio Stranges, Rayman, Margaret P, Pastor-Barriuso, R., Holger Steinbrenner (135147), Steinbrenner, H, Rayman, MP, Saverio Stranges (73786), Pastor-Barriuso Roberto, Margaret P. Rayman (135136), Rayman Margaret P., Guallar Eliseo   +31 more
core   +2 more sources

In silico identification of the sea squirt selenoproteome

BMC Genomics, 2010
Background Computational methods for identifying selenoproteins have been developed rapidly in recent years. However, it is still difficult to identify the open reading frame (ORF) of eukaryotic selenoprotein gene, because the TGA codon for a ...
Jiang Liang, Liu Qiong, Ni Jiazuan
doaj   +1 more source

Inhibition of selenoprotein synthesis by Zika virus may contribute to congenital Zika syndrome and microcephaly by mimicking SELENOP knockout and the genetic disease PCCA

BBA Advances, 2021
Selenium status plays a major role in health impacts of various RNA viruses. We previously reported potential antisense interactions between viral mRNAs and host mRNAs encoding isoforms of the antioxidant selenoprotein thioredoxin reductase (TXNRD). Here,
Gabrielle P. Dailey, Lakmini S. Premadasa, Jan A. Ruzicka, Ethan Will Taylor   +3 more
doaj   +1 more source

Evaluation of Selenoprotein Supplementation on Digestibility, Growth, and Health Performance of Pacific White Shrimp Litopenaeus vannamei

Aquaculture Nutrition, 2023
Selenoprotein is a feed additive that can overcome oxidative stress in intensive Pacific white shrimp (Litopenaeus vannamei) culture. This study evaluated the effects of selenoprotein supplementation at various doses on Pacific white shrimp’s ...
Rafi Kemal, Ichsan Achmad Fauzi, Sri Nuryati, Wira Wisnu Wardani, Muhammad Agus Suprayudi   +4 more
doaj   +1 more source

SEPP1 (selenoprotein P, plasma, 1) [PDF]

, 2011
Review on SEPP1 (selenoprotein P, plasma, 1), with data on DNA, on the protein encoded, and where the gene is ...
Jablonska, E, Gromadzinska, J, Wasowicz, W, Reszka, E   +3 more
core   +1 more source

Dietary supplementation with selenomethionine enhances antioxidant capacity and selenoprotein gene expression in layer breeder roosters

Poultry Science, 2022
: This study's objective was to investigate the effects of dietary Se (in the form of selenomethionine) on the antioxidant activity and selenoprotein gene expressions in layer breeder roosters.
Cheng Long, Guan-Yu Zhu, Xi-Hui Sheng, Kai Xing, Koen Venema, Xiang-Guo Wang, Long-Fei Xiao, Yong Guo, He-Min Ni, Nian-Hua Zhu, Xiao-Long Qi   +10 more
doaj   +1 more source

Associations and interactions between variants in selenoprotein genes, selenoprotein levels and the development of abdominal aortic aneurysm, peripheral arterial disease, and heart failure. [PDF]

PLoS ONE, 2018
BACKGROUND:Little is known on the role of selenoprotein genes in cardiovascular disease. This study examines the associations of the SEPP1, SELENOS, TXNRD1, TXNRD2, GPX4, and SOD2 polymorphisms and selenoprotein P (SeP) and thioredoxin concentrations ...
Ewa Strauss, Jolanta Tomczak, Ryszard Staniszewski, Grzegorz Oszkinis   +3 more
doaj   +1 more source

Table_1_Alcohol Intake Is Associated With Elevated Serum Levels of Selenium and Selenoprotein P in Humans.docx

, 2021
Selenoprotein P is a hepatokine with antioxidative properties that eliminate a physiologic burst of reactive oxygen species required for intracellular signal transduction.
Yuki Isobe (2898251), Hiroyuki Nakamura (200082), Takehiro Kanamori (8255321), Hiromasa Tsujiguchi (4258522), Atsushi Tajima (40311), Akinori Hara (452250), Takayuki Kannon (10175561), Yumie Takeshita (307060), Hiroki Asakura (4258519), Toshinari Takamura (158655), Kiyo-aki Ishii (10175564), Tatsuya Yamashita (3067323), Shuichi Kaneko (156576), Hiroaki Takayama (2530507)   +13 more
core   +1 more source

Selenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression

BMC Immunology, 2009
Background Selenium, a micronutrient whose deficiency in diet causes immune dysfunction and inflammatory disorders, is thought to exert its physiological effects mostly in the form of selenium-containing proteins (selenoproteins).
Gladyshev Vadim N, Irons Robert, Kim Jin, Sengupta Aniruddha, Sano Yasuyo, Yoo Min-Hyuk, Carlson Bradley A, Hatfield Dolph L, Park Jin   +8 more
doaj   +1 more source