Results 11 to 20 of about 17,575 (209)

Selenoprotein gene nomenclature [PDF]

Journal of Biological Chemistry, 2016
The human genome contains 25 genes coding for selenocysteine-containing proteins (selenoproteins). These proteins are involved in a variety of functions, most notably redox homeostasis.
Arn\ue9r, Elias S., Berry, Marla J., Bruford, Elspeth A., Burk, Raymond F., Carlson, Bradley A., Castellano, Sergi, Chavatte, Laurent, Conrad, Marcus, Copeland, Paul R., Diamond, Alan M., Driscoll, Donna M., Ferreiro, Ana, Floh\ue9, Leopold, Gladyshev, Vadim N, Green, Fiona R., Guig\uf3, Roderic, Handy, Diane E., Hatfield, Dolph L., Hesketh, John, Hoffmann, Peter R., Holmgren, Arne, Hondal, Robert J., Howard, Michael T., Huang, Kaixun, K\uf6hrle, Josef, Kim, Hwa Young, Kim, Ick Young, Krol, Alain, Kryukov, Gregory V., Lee, Byeong Jae, Lee, Byung Cheon, Lei, Xin Gen, Lescure, Alain, Liu, Qiong, Lobanov, Alexei V., Loscalzo, Joseph, Maiorino, Matilde, Mariotti, Marco, Prabhu, K. Sandeep, Rayman, Margaret P., Regina, Brigelius Floh\ue9, Rozovsky, Sharon, Salinas, Gustavo, Schmidt, Edward E., Schomburg, Lutz, Schweizer, Ulrich, Simonovi\u107, Miljan, Sunde, Roger A., Tsuji, Petra A., Tweedie, Susan, Ursini, Fulvio, Whanger, Philip D., Zhang, Yan   +52 more
core   +5 more sources

Immune aging impairs muscle regeneration via macrophage-derived anti-oxidant selenoprotein P [PDF]

EMBO Reports
Muscle regeneration is impaired with aging, due to both intrinsic defects of muscle stem cells (MuSCs) and alterations of their niche. Here, we monitor the cells constituting the MuSC niche over time in young and old regenerating mouse muscle.
Dieu-Huong Hoang, Jessica Bouvière, Johanna Galvis, Pauline Moullé, Orane Mercier, Eugenia Migliavacca, Ananga Ghosh, Gaëtan Juban, Sophie Liot, Pascal Stuelsatz, Fabien Le Grand, Jérôme N Feige, Rémi Mounier, Bénédicte Chazaud   +13 more
doaj   +3 more sources

A positive effect of selenoprotein on mammary gland: Selenoprotein P stabilizes tight junctions by reducing cell death through inflammation mitigation in mice [PDF]

Redox Biology
Lactational mastitis threatens maternal-infant health and animal husbandry efficiency, with traditional antibiotics limited by milk residues and bacterial resistance.
Mengran Zhu, Tianchao Xu, Hongli Lv, Yuxi Zhang, Jilong Luo, Mengyao Guo   +5 more
doaj   +2 more sources

A Pan-Cancer Analysis of the Role of Selenoprotein P mRNA in Tumorigenesis [PDF]

International Journal of General Medicine, 2021
Yanni Yang,1– 3,* Daning Li,1,* Wentao Wu,1 Dingxing Huang,1 Haishi Zheng,3 Yirixiati Aihaiti3 1School of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, People’s Republic of China; 2Shaanxi University of ...
Yang Y, Li D, Wu W, Huang D, Zheng H, Aihaiti Y   +5 more
doaj   +2 more sources

Investigation of The Placental Levels of Vascular Endothelial Growth Factor B and Selenoprotein P and Their Relation with Birth Weight in Patients with Pre-eclampsia: A Case-Control Study [PDF]

International Journal of Fertility and Sterility
Background: Pre-eclampsia is a serious medical condition characterised by high blood pressure and signs of organdamage that is associated with adverse pregnancy outcomes, including low birth weight.
Hadi Eslahi, Mohsen Saravani, Mansour Shahraki, Abolfazl Payandeh, Mahnaz Rezaei, Marzieh Ghasemi, Saeedeh Salimi, Mahjob Sargazi-Taghazi   +7 more
doaj   +2 more sources

New-onset autoantibodies to selenoprotein P following severe burn injury [PDF]

Frontiers in Immunology
The liver-derived selenium (Se) transporter selenoprotein P (SELENOP) declines in critical illness as a negative acute phase reactant and has recently been identified as an autoantigen.
Tabael L. Turan, Holger J. Klein, Holger J. Klein, Theresia Reding Graf, Thilo Samson Chillon, Jan A. Plock, Jan A. Plock, Lutz Schomburg   +7 more
doaj   +2 more sources

Circulating selenoprotein P levels predict glucose‐lowering and insulinotropic effects of metformin, but not alogliptin: A post‐hoc analysis [PDF]

Journal of Diabetes Investigation, 2023
Aims/Introduction Selenoprotein P (SeP; encoded by SEPP1 in humans) is a hepatokine that causes impaired insulin secretion and insulin resistance. Metformin downregulates SELENOP promoter activity through an adenosine monophosphate‐activated kinase ...
Yumie Takeshita, Takeo Tanaka, Hiroaki Takayama, Yuki Kita, Hisanori Goto, Yujiro Nakano, Yoshiro Saito, Toshinari Takamura   +7 more
doaj   +2 more sources

A County-Level Spatial Study of Serum Selenoprotein P and Keshan Disease [PDF]

Frontiers in Nutrition, 2022
BackgroundKeshan disease (KD) is strongly associated with selenium deficiency. Selenoprotein P (SELENOP) is a recognized molecular biomarker of selenoproteins and an important indicator of selenium nutrition.
Yuehui Jia, Ruixiang Wang, Shengqi Su, Lei Qi, Yuanyuan Wang, Yanan Wang, Yanan Wang, Yuanjie Zou, Yuanjie Zou, Xu Liu, Xu Liu, Yiyi Zhang, Yiyi Zhang, Jie Hou, Hongqi Feng, Qi Li, Tong Wang   +16 more
doaj   +2 more sources

Alcohol Intake Is Associated With Elevated Serum Levels of Selenium and Selenoprotein P in Humans

Frontiers in Nutrition, 2021
Selenoprotein P is a hepatokine with antioxidative properties that eliminate a physiologic burst of reactive oxygen species required for intracellular signal transduction.
Yuki Isobe, Hiroki Asakura, Hiromasa Tsujiguchi, Takayuki Kannon, Hiroaki Takayama, Yumie Takeshita, Kiyo-aki Ishii, Takehiro Kanamori, Akinori Hara, Tatsuya Yamashita, Atsushi Tajima, Shuichi Kaneko, Hiroyuki Nakamura, Toshinari Takamura   +13 more
doaj   +1 more source

A randomized trial of selenium supplementation and risk of type-2 diabetes, as assessed by plasma adiponectin [PDF]

, 2012
Background: Evidence that selenium affects the risk of type-2 diabetes is conflicting, with observational studies and a few randomized trials showing both lower and higher risk linked to the level of selenium intake and status. We investigated the effect
Eliseo Guallar, Gabrielle Blundell-Pound, Guoying Wang, Holger Steinbrenner, Margaret P. Rayman, Roberto Pastor-Barriuso, Saverio Stranges   +6 more
core   +12 more sources