Alcohol Intake Is Associated With Elevated Serum Levels of Selenium and Selenoprotein P in Humans [PDF]
Frontiers in Nutrition, 2021 Selenoprotein P is a hepatokine with antioxidative properties that eliminate a physiologic burst of reactive oxygen species required for intracellular signal transduction.
Yuki Isobe +13 more
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Role of microRNA-7 and selenoprotein P in hepatocellular carcinoma
Tumor Biology, 2017 There is an obvious need to diagnose hepatocellular carcinoma using novel non-invasive and sensitive biomarkers. In this regard, the aim of this study was to evaluate and correlate both relative quantification of microRNA-7 using quantitative real time ...
Marwa Tarek +5 more
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Aminoglycoside-driven biosynthesis of selenium-deficient Selenoprotein P [PDF]
Scientific Reports, 2017 Selenoprotein biosynthesis relies on the co-translational insertion of selenocysteine in response to UGA codons. Aminoglycoside antibiotics interfere with ribosomal function and may cause codon misreading.
Kostja Renko +11 more
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Altered hippocampus synaptic function in selenoprotein P deficient mice [PDF]
Molecular Neurodegeneration, 2006 Selenium is an essential micronutrient that function through selenoproteins. Selenium deficiency results in lower concentrations of selenium and selenoproteins.
Peters Melinda M +3 more
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A spatial study on Keshan disease prevalence and selenoprotein P in the Heilongjiang Province, China [PDF]
International Journal of Occupational Medicine and Environmental Health, 2021 Objectives Few spatial studies on Keshan disease (KD) prevalence and serum selenoprotein P (SELENOP) levels have been reported in the Heilongjiang Province, China.
Yanan Wang +8 more
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A Pan-Cancer Analysis of the Role of Selenoprotein P mRNA in Tumorigenesis [PDF]
International Journal of General Medicine, 2021 Yanni Yang,1– 3,* Daning Li,1,* Wentao Wu,1 Dingxing Huang,1 Haishi Zheng,3 Yirixiati Aihaiti3 1School of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, People’s Republic of China; 2Shaanxi University of ...
Yang Y +5 more
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Circulating selenoprotein P levels predict glucose‐lowering and insulinotropic effects of metformin, but not alogliptin: A post‐hoc analysis [PDF]
Journal of Diabetes Investigation, 2023 Aims/Introduction Selenoprotein P (SeP; encoded by SEPP1 in humans) is a hepatokine that causes impaired insulin secretion and insulin resistance. Metformin downregulates SELENOP promoter activity through an adenosine monophosphate‐activated kinase ...
Yumie Takeshita +7 more
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Investigation of The Placental Levels of Vascular Endothelial Growth Factor B and Selenoprotein P and Their Relation with Birth Weight in Patients with Pre-eclampsia: A Case-Control Study [PDF]
International Journal of Fertility and SterilityBackground: Pre-eclampsia is a serious medical condition characterised by high blood pressure and signs of organdamage that is associated with adverse pregnancy outcomes, including low birth weight.
Hadi Eslahi +7 more
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Predictive Value of Selenoprotein P in Newly Diagnosed Type 2 Diabetes: A Diagnostic Accuracy Study
Endocrinology Research and PracticeObjective: To investigate levels of selenoprotein P (SeP), a liver-derived hepatokine, in patients with newly diagnosed type 2 diabetes mellitus (T2DM) compared with healthy controls and to evaluate its relationship with metabolic indicators. Methods:
Gürkan Yarbaş +3 more
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The semisynthesis of nucleolar human selenoprotein H [PDF]
, 2023 The human selenoprotein H is the only selenocysteine-containing protein that is located in the cell’s nucleolus. In vivo studies have suggested that it plays some role in DNA binding, consumption of reactive oxygen species, and may serve as a safeguard ...
Rebecca , Notis Dardashti +1 more
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