Results 21 to 30 of about 10,363 (168)
Frontiers in Animal Science, 2022 Many supplemental Se-dependent metabolic effects are mediated through the function of selenoproteins. The full complement and relative abundance of selenoproteins expressed by highly metabolic cattle tissues have not been characterized in cattle.
Qing Li +3 more
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Selenoprotein P regulation by the glucocorticoid receptor [PDF]
BioMetals, 2009 Maintenance of the antioxidant activity of selenoproteins is one potential mechanism of the beneficial health effects of selenium. Selenoprotein P is the primary selenium distribution protein of the body as well as the major selenium containing protein in serum.
Colleen, Rock, Philip J, Moos
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Selenoprotein P in colitis-associated carcinoma [PDF]
Molecular & Cellular Oncology, 2016 Patients with inflammatory bowel disease are often deficient in micronutrients such as selenium and have an increased risk of colon cancer. We tested whether the selenium transport protein, selenoprotein P, could modify colitis-associated cancer. Our results indicate that global SEPP1 haploinsufficiency augments tumorigenesis and mediates oxidative ...
Sarah P, Short +2 more
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Serum Selenoprotein P level is not indicative of Insulin Resistance in Children and Adolescents with Type 1 Diabetes Mellitus: Single Center Experience [PDF]
Pediatric Sciences Journal (Egypt), 2022 Background: Selenium has an anti-diabetic action as it an insulin-mimetic and antioxidant nutrient. Selenoprotein P (SeP) is an extracellular glycoprotein, that was linked to insulin resistance (IR).
Hend Mehawed Soliman +3 more
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Localization and regulation of pancreatic selenoprotein P [PDF]
Journal of Molecular Endocrinology, 2012 Progressive loss of pancreatic β-cell mass is a crucial feature of type 2 diabetes mellitus. As β-cells express very low amounts of the antioxidant enzymes catalase and glutathione peroxidase (GPx), they appear to be particularly vulnerable to oxidative damage in the pathogenesis of diabetes.
Holger, Steinbrenner +8 more
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BMC Genomics, 2010 Background Computational methods for identifying selenoproteins have been developed rapidly in recent years. However, it is still difficult to identify the open reading frame (ORF) of eukaryotic selenoprotein gene, because the TGA codon for a ...
Jiang Liang, Liu Qiong, Ni Jiazuan
doaj +1 more source
Aquaculture Nutrition, 2023 Selenoprotein is a feed additive that can overcome oxidative stress in intensive Pacific white shrimp (Litopenaeus vannamei) culture. This study evaluated the effects of selenoprotein supplementation at various doses on Pacific white shrimp’s ...
Rafi Kemal +4 more
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BBA Advances, 2021 Selenium status plays a major role in health impacts of various RNA viruses. We previously reported potential antisense interactions between viral mRNAs and host mRNAs encoding isoforms of the antioxidant selenoprotein thioredoxin reductase (TXNRD). Here,
Gabrielle P. Dailey +3 more
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Selenoprotein Metabolism and Function: Evidence for More than One Function for Selenoprotein P [PDF]
The Journal of Nutrition, 2003 Biological functions of selenium are exerted by selenoproteins that contain selenocysteine in their primary structure. Selenocysteine is synthesized and inserted into proteins cotranslationally by a complex process. Families of selenoproteins include the glutathione peroxidases, the iodothyronine deiodinases and the thioredoxin reductases.
Raymond F, Burk +2 more
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Selenoprotein P; P for Plasma, Prognosis, Prophylaxis, and More
Biological and Pharmaceutical Bulletin, 2020 Selenoprotein P (SeP) is one of the 25 human selenocysteine (Sec)-containing proteins, and is generally thought to function as a plasma carrier of the trace element selenium in the body. Recent studies, however, indicate unsuspected pivotal roles of SeP in human diseases, particularly in type 2 diabetes mellitus (T2DM) and pulmonary arterial ...
Tsutsumi, Ryouhei, Saito, Yoshiro
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