Results 21 to 30 of about 24,108,879 (155)

Increases in Hepatokine Selenoprotein P Levels Are Associated With Hepatic Hypoperfusion and Predict Adverse Prognosis in Patients With Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Although multiorgan networks are involved in the pathophysiology of heart failure (HF), interactions of the heart and the liver have not been fully understood.
Ryohei Takeishi, Tomofumi Misaka, Yasuhiro Ichijo, Shinji Ishibashi, Mitsuko Matsuda, Yukio Yamadera, Himika Ohara, Yukiko Sugawara, Yu Hotsuki, Koichiro Watanabe, Fumiya Anzai, Yu Sato, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Kazuhiko Nakazato, Akiomi Yoshihisa, Yasuchika Takeishi   +18 more
doaj   +1 more source

The selenium content of SEPP1 versus selenium requirements in vertebrates [PDF]

PeerJ, 2015
Selenoprotein P (SEPP1) distributes selenium (Se) throughout the body via the circulatory system. For vertebrates, the Se content of SEPP1 varies from 7 to 18 Se atoms depending on the species, but the reason for this variation remains unclear. Herein we
Sam Penglase, Kristin Hamre, Ståle Ellingsen   +2 more
doaj   +2 more sources

Selenoprotein P levels in patients with diabetes mellitus with complications [PDF]

, 2022
Aims: Increasing evidence has shown that selenoprotein P levels are elevated in type 2 diabetes mellitus and are associated with insulin resistance and release.
Yücel, Hasan Esat, Ilanbey, Bilal, Kocamış, Özkan, Uçar, Cahit   +3 more
core   +1 more source

Selenoprotein gene nomenclature [PDF]

, 2016
The human genome contains 25 genes coding for selenocysteine-containing proteins (selenoproteins). These proteins are involved in a variety of functions, most notably redox homeostasis.
Rayman, M.P., Kim, HY, Sunde, Roger,, Green, F.R., Hondal, R., Hesketh, John, Tsuji, Petra A., Tweedie, S, Flohé, Leopold, Köhrle, J., Burk, Raymond,, Ursini, F, Lei, X.G., Prabhu, K., Ursini, F.F., Kim, I., Diamond, A.M., Burk, Raymond F., Brigelius-Flohé, R., Whanger, Philip,, Lee, B.C., Hondal, RJ, Driscoll, D.M., Conrad, Marcus, Copeland, PR, Green, FR, Berry, M.J., Prabhu, KS, Carlson, B.A., Salinas, G, Hatfield, Dolph,, Rayman, Margaret,, Simonović, M, Bruford, Elspeth, A., Driscoll, D., Ferreiro, Ana, Kim, H., Loscalzo, Joseph, Maiorino, M, Lobanov, Alexei, V., Schmidt, Edward E., Handy, Diane,, Handy, D., Liu, Q, Hatfield, Dolph L., Krol, Alain, Schomburg, L, Schweizer, U., Hoffmann, P., Liu, Qiong, Lobanov, A., Howard, Michael,, Guigó, R., Hoffmann, P.R., Driscoll, DM, Handy, DE, Lobanov, A.V., Gladyshev, Vadim N, Tsuji, P.A., Hoffmann, Peter, R., Hondal, R.J., Kim, IY, Hoffmann, PR, Zhang, Y, Sunde, R.A., Berry, Marla J., Copeland, P., Hatfield, D.L., Mariotti, M, Salinas, G., Conrad, M, Hoffmann, Peter R., Kryukov, Gregory V., Tsuji, Petra, A., Regina, Brigelius Flohé, Whanger, PD, Howard, M.T., Köhrle, J, Howard, Michael T., Burk, Raymond, F., Whanger, P., Kim, Hwa-Young, Sunde, RA, Conrad, M., Schmidt, Edward, E., Handy, Diane, E., Guigó, Roderic, Berry, M., URSINI, FULVIO, Lobanov, AV, Schomburg, L., Lescure, Alain, Mariotti, Marco, Copeland, Paul R., Huang, Kaixun, Ferreiro, A., Whanger, P.D., Holmgren, Arne, Carlson, Bradley A., Handy, Diane E., Sunde, Roger A., Holmgren, A, Arner, E.S.J., Krol, A., Green, Fiona, R., Salinas, Gustavo, Kim, Hwa Young, Rozovsky, S, Gladyshev, Vadim, N., Copeland, Paul, R., Arnér, Elias S., Carlson, B., Lee, B., Lee, Byeong Jae, Kryukov, G.V., Schmidt, Edward,, Liu, Q., Schmidt, E., Kim, Ick Young, Green, F., Berry, Marla,, Sunde, R., Castellano, S., Rayman, Margaret P., Bruford, Elspeth,, Lee, BC, Huang, K, Schmidt, EE, Lee, BJ, Whanger, Philip D., Copeland, Paul,, Gladyshev, V.N., Hondal, Robert, J., Driscoll, Donna M., Zhang, Y., Chavatte, L, Hondal, Robert,, Gladyshev, VN, Zhang, Yan, Huang, K., Diamond, AM, Loscalzo, J, Arnér, E., Castellano, S, Rozovsky, S., Carlson, BA, Ferreiro, A, Chavatte, L., Lescure, A., Arnér, Elias, S., Green, Fiona,, Berry, MJ, Berry, Marla, J., Lee, B.J., Loscalzo, J., Brigelius-Flohé, Regina, Lei, Xin Gen, Diamond, Alan,, Prabhu, K.S., Carlson, Bradley,, Arnér, ES, Driscoll, Donna, M., Schomburg, Lutz, Burk, RF, Kim, H.Y., Bruford, Elspeth A., Lee, Byung Cheon, Driscoll, Donna,, Krol, A, Hesketh, J., Chavatte, Laurent, Mariotti, M., Hesketh, J, Huang, K.M., Gladyshev, Vadim,, Diamond, Alan, M., Rozovsky, Sharon, Maiorino, M., Handy, D.E., Diamond, A., Regina, B.F., Hatfield, D., Kryukov, Gregory,, Flohé, L., Tweedie, S., MAIORINO, MATILDE, Schweizer, Ulrich, Bruford, E.A., Burk, R.F., Sunde, Roger, A., Rayman, M., Schweizer, U, Kryukov, GV, Carlson, Bradley, A., Prabhu, K. Sandeep, Kryukov, G., Bruford, E., Green, Fiona R., Hatfield, Dolph, L., Lei, X., Rayman, MP, Whanger, Philip, D., Burk, R., Copeland, P.R., Arnér, Elias,, Howard, M., Brigelius-Flohé, R, Guigó, R, Lobanov, Alexei,, Castellano, Sergi, Schmidt, E.E., Tsuji, PA, Bruford, EA, Flohé, L, Sandeep Prabhu, K., Kryukov, Gregory, V., Tsuji, P., Lescure, A, Lei, XG, Tweedie, Susan, Hatfield, DL, Simonovic, M., Howard, MT, Holmgren, A., Ursini, F., Lobanov, Alexei V., Rayman, Margaret, P., Hondal, Robert J., Hoffmann, Peter,, Howard, Michael, T., Simonović, Miljan, Kim, I.Y., Gladyshev, V., Tsuji, Petra,, Köhrle, Josef, Diamond, Alan M., Castellano, S. ; https://orcid.org/   +236 more
core   +3 more sources

Analysis of the selenoprotein P (rs7579) gene polymorphism and expression in patients with chronic pancreatitis combined with hypothyroidism

Mìžnarodnij Endokrinologìčnij Žurnal, 2023
Background. The specific role and place of genetic factors in the development of chronic pancreatitis and hypothyroidism, which determine the activity of glutathione antioxidant protection, have not been clarified. They are interconnected with changes in
V.V. Ratsa, O.I. Fediv, L.P. Sydorchuk, Z.I. Rossokha, O.I. Sydorchuk, V.T. Stepan, I.O. Buzdugan   +6 more
doaj   +1 more source

Selenoprotein P controls oxidative stress in cornea. [PDF]

PLoS ONE, 2010
The ocular surface is always attacked by oxidative stress, and cornea epithelial cells are supposed to have their own recovery system against oxidative stress.
Akihiro Higuchi, Kazuhiko Takahashi, Masaki Hirashima, Tetsuya Kawakita, Kazuo Tsubota   +4 more
doaj   +1 more source

A novel protein kinase-like domain in a selenoprotein, widespread in the tree of life. [PDF]

, 2012
Selenoproteins serve important functions in many organisms, usually providing essential oxidoreductase enzymatic activity, often for defense against toxic xenobiotic substances.
Marcin Grynberg, Grynberg Marcin, Dudkiewicz, Małgorzata, Marcin Grynberg (183714), Szczepińska Teresa, Grynberg, Marcin, Krzysztof Pawłowski, Małgorzata Dudkiewicz (183704), Teresa Szczepińska (183708), Dudkiewicz Małgorzata, Małgorzata Dudkiewicz, Pawłowski Krzysztof, Teresa Szczepińska, Pawłowski, Krzysztof, Krzysztof Pawłowski (183717), Szczepińska, Teresa   +15 more
core   +2 more sources

Human selenoprotein P and S variant mRNAs with different numbers of SECIS elements and inferences from mutant mice of the roles of multiple SECIS elements [PDF]

Open Biology, 2016
Dynamic redefinition of the 10 UGAs in human and mouse selenoprotein P (Sepp1) mRNAs to specify selenocysteine instead of termination involves two 3′ UTR structural elements (SECIS) and is regulated by selenium availability. In addition to the previously
Sen Wu, Marco Mariotti, Didac Santesmasses, Kristina E. Hill, Janinah Baclaocos, Estel Aparicio-Prat, Shuping Li, John Mackrill, Yuanyuan Wu, Michael T. Howard, Mario Capecchi, Roderic Guigó, Raymond F. Burk, John F. Atkins   +13 more
doaj   +1 more source

Pituitary and liver selenoprotein transcriptome profiles of grazing steers and their sensitivity to the form of selenium in vitamin-mineral mixes

Frontiers in Animal Science, 2022
Many supplemental Se-dependent metabolic effects are mediated through the function of selenoproteins. The full complement and relative abundance of selenoproteins expressed by highly metabolic cattle tissues have not been characterized in cattle.
Qing Li, Kuey C. Chen, Phillip J. Bridges, James C. Matthews   +3 more
doaj   +1 more source

Serum Selenoprotein P level is not indicative of Insulin Resistance in Children and Adolescents with Type 1 Diabetes Mellitus: Single Center Experience [PDF]

Pediatric Sciences Journal (Egypt), 2022
Background: Selenium has an anti-diabetic action as it an insulin-mimetic and antioxidant nutrient. Selenoprotein P (SeP) is an extracellular glycoprotein, that was linked to insulin resistance (IR).
Hend Mehawed Soliman, Balsam Sherif Fahmy, Selim Mohamed Abdelkader, Samah A. Hassanein   +3 more
doaj   +1 more source