Results 151 to 160 of about 20,710 (205)

Reagentless Real-Time ATP Monitoring with New DNA Aptamers. [PDF]

Small
Bacon A, Alkhamis O, Byrd C, Perry J, Canoura J, Xiao Y.   +5 more
europepmc   +1 more source

Design and Characterization of Aptamers to Antibiotic Kanamycin with Improved Affinity. [PDF]

Int J Mol Sci
Samokhvalov AV, Maksimenko OG, Zherdev AV, Dzantiev BB.   +3 more
europepmc   +1 more source

Aptamers as emerging tools for plant disease management: From biosensing to active modulation. [PDF]

iScience
Liu F, Zhang Y, Wei Z, Wu H, Jia Y, Li X.   +5 more
europepmc   +1 more source

eIF3g binding to GUCG boxes located in mRNA coding regions enhances translation of mild heat shock response genes in the yeast Saccharomyces cerevisiae. [PDF]

Nucleic Acids Res
Kato H, Oguro A, Mao Y, Ochsner K, Casey H, Sakai G, Wan J, Usuki S, Tang L, Asano M, Bardiya N, Kaufman K, Ishiguro S, Tani N, Kumagai K, Nakamura A, Singh CR, Sakamoto T, Obayashi E, Qian SB, Asano K.   +20 more
europepmc   +1 more source

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Quantitative Comparison of Capture-SELEX, GO-SELEX, and Gold-SELEX for Enrichment of Aptamers

Analytical Chemistry, 2023
Since 1990, numerous methods for aptamer selection have been developed, although a quantitative comparison of their sequence enrichment is lacking. In this study, we compared the enrichment factors of three library-immobilization SELEX methods (capture-SELEX, GO-SELEX, and gold-SELEX).
Yuzhe Ding, Juewen Liu
openaire   +2 more sources

Methods developed for SELEX

Analytical and Bioanalytical Chemistry, 2006
SELEX (systematic evolution of ligands by exponential enrichment) is a process that involves the progressive purification from a combinatorial library of nucleic acid ligands with a high affinity for a particular target by repeated rounds of partitioning and amplification.
Subash C B Gopinath
exaly   +3 more sources

Complex Target SELEX

Accounts of Chemical Research, 2008
Aptamers are non-naturally occurring structured oligonucleotides that may bind to small molecules, peptides, and proteins. Typically, aptamers are generated by an in vitro selection process referred to as SELEX (systematic evolution of ligands by exponential enrichment).
Steven M, Shamah, Judith M, Healy, Sharon T, Cload   +2 more
openaire   +2 more sources

SELEX with modified nucleotides

Current Opinion in Chemical Biology, 2008
Aptamers, a promising new class of therapeutics, are single-stranded oligonucleotides generated via an in vitro selection process that bind to and inhibit the activity of target proteins in a manner similar to therapeutic antibodies. In order to enhance the drug-like character of aptamers, oligonucleotide libraries containing modified nucleotides are ...
Anthony D, Keefe, Sharon T, Cload
openaire   +2 more sources

Non-SELEX Selection of Aptamers

Journal of the American Chemical Society, 2006
Aptamers are typically selected from libraries of random DNA (or RNA) sequences by SELEX, which involves multiple rounds of alternating steps of partitioning and PCR amplification. Here we report, for the first time, non-SELEX selection of aptamers-a process that involves repetitive steps of partitioning with no amplification between them.
Maxim V Berezovski, Michael U Musheev, Andrei Drabovich   +2 more
exaly   +3 more sources