Results 191 to 200 of about 12,731 (219)

Genomic SELEX for the genome-wide search of regulation targets by transcription factors: SELEX-clos and SELEX-chip procedures

2009 International Symposium on Micro-NanoMechatronics and Human Science, 2009
The pattern of genome transcription in prokaryotes is determined by selective distribution of RNA polymerase within the genome. The gene selectivity of RNA polymerase is modulated after interaction with DNA-binding transcription factors (TFs). Escherichia coli contains a total of about 300 TFs, but the regulatory function has not yet been identified ...
Tomohiro Shimada, Nobuyuki Fujita, Kaneyoshi Yamamoto, Akira Ishihama   +3 more
openaire   +1 more source

Enhanced SELEX Platforms for Aptamer Selection with Improved Characteristics: A Review

Molecular Biotechnology
Yildirim, Nimet/0000-0002-5973-8830This review delves into the advancements in molecular recognition through enhanced SELEX (Systematic Evolution of Ligands by Exponential Enrichment) platforms and post-aptamer modifications.
Reza Didarian, Veli Cengiz Özalp, Nimet Yildirim-Tirgil   +2 more
exaly   +2 more sources

The Selex design pattern

Proceedings of the 14th Conference on Pattern Languages of Programs, 2007
State machine specifications and their implementations are often complex because they have many responsibilities mixed together. A potential cause for responsibility clutter is message multiplexing, which means that one or more incoming and/or outgoing messages of the state machine contain data that belongs to different concerns.
Frank Roessler, Birgit Geppert
openaire   +1 more source

SELEX: Just another separation?

The Analyst, 2005
The potential for quickly isolating high affinity, highly selective ligands generated much excitement when SELEX was first described. Fifteen years later, SELEX has still not achieved widespread acceptance due to limitations in aptamer affinity, stability and throughput.
openaire   +2 more sources

Multifaceted arsenal in SELEX nanomedicine

Advances in Colloid and Interface Science
Aptamers, short oligonucleotide sequences that bind specifically to cellular proteins and receptors, are emerging as versatile tools in molecular nanomedicine. Unlike passive tumor targeting via the enhanced permeability and retention (EPR) effect, aptamers enable precise drug delivery, enhancing therapeutic efficacy while minimizing side effects ...
Oishika, Chatterjee, Gun Anit, Kaur, Nutan, Shukla, Sapna, Balayan, Pravin Kumar, Singh, Subhrangsu, Chatterjee, Ashutosh, Tiwari   +6 more
openaire   +2 more sources

SELEX

2022
Chenxi Liang, Peixuan Guo
openaire   +1 more source

The SELEX experiment at Fermilab

AIP Conference Proceedings, 1998
The SELEX experiment (Segmented Large-X Spectrometer) has been taking data in the 1996–7 Fermilab fixed-target run. The experiment uses a 650 GeV/c negative beam which is 50% Σ−, 50% π−. The primary purpose is to study the production and properties of charmed and charm-strange baryons, but there is also a wide program of other physics topics.
openaire   +1 more source

Aptamers and SELEX: the technology

World Patent Information, 2003
Abstract DNA and RNA microarrays have become an important analytical technique in the understanding and characterisation of genomes and transcriptomes. A recent development in this field of combinatorial chemistry has concentrated on using artificial DNA/RNA sequences––aptamers––as the screening ligand.
openaire   +1 more source

SELEX in silico

2013
Poster Presentations: Theme 1 - Cancer: abstract no.
Tanner, JA, Kinghorn, A
openaire   +1 more source

Capture-SELEX for aptamer selection: A short review

Talanta, 2021
Imran Mahmood Khan, Zhouping Wang
exaly