Results 61 to 70 of about 610,157 (345)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Robust iterative learning control for uncertain continuous‐time system with input delay and random iteration‐varying uncertainties

IET Control Theory & Applications, 2021
This study deals with the problem of robust iterative learning control (ILC) for linear continuous‐time systems with input delay subject to uncertainties in input delay, plant dynamic, reference trajectory, initial conditions and disturbances.
Hamid Shokri‐Ghaleh, Soheil Ganjefar, Alireza Mohammad Shahri   +2 more
doaj   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

DYNAMICO: A Reference Model for Governing Control Objectives and Context Relevance in Self-Adaptive Software Systems

, 2010
Despite the valuable contributions on self-adaptation, most implemented approaches assume adaptation goals and monitoring infrastructures as non-mutable, thus constraining their applicability to systems whose context awareness is restricted to static ...
Casallas, Rubby, Müller, Hausi A., Villegas, Norha Milena, Duchien, Laurence, Tamura Morimitsu, Gabriel   +4 more
core   +1 more source

Control of self-organizing nonlinear systems

, 2016
The book summarizes the state-of-the-art of research on control of self-organizing nonlinear systems with contributions from leading international experts in the field.
Klapp, Sabine, Hövel, Philipp, Schöll, Eckehard   +2 more
core   +2 more sources

A fuzzy adaptive admittance controller for force tracking in an uncertain contact environment

IET Control Theory & Applications, 2021
Traditional constant admittance controller (CAC) in uncertain contact environment is highly dependent on environmental location and stiffness, which are always difficult to obtain in most applications. To address this problem, a fuzzy adaptive admittance
Zhisen Li, Hailin Huang, Xiaogang Song, Wenfu Xu, Bing Li   +4 more
doaj   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

Software Engineering Meets Control Theory [PDF]

, 2015
International audienceThe software engineering community has proposed numerous approaches for making software self-adaptive. These approaches take inspiration from machine learning and control theory, constructing software that monitors and modifies its ...
Ilias Gerostathopoulos, Papadopoulos, Alessandro,, Krikava, Filip, Jamshidi, Pooyan, Hoffmann, H, Sharifloo, Amir M., Sharifloo, AM, Andreas Berndt Hempel, Evangelia Kalyvianaki, Vogel, T, Ray, Suprio, Maggio, M, Hempel, Andreas, Hempel, AB, Sasa Misailovic, Angelopoulos, Konstantinos, Cristian Klein, Hoffmann, Henry, Filip Krikava, D'Ippolito, Nicolas, Shevtsov, Stepan,, Henry Hoffmann, Papadopoulos, Alessandro Vittorio,, Thomas Vogel, Amir M. Sharifloo, Ujma, M, Maggio, Martina, Pooyan Jamshidi, Berndt Hempel, Andreas, Shevtsov, Stepan, Filieri, Antonio, Kalyvianaki, E, Misailovic, S, Nicolas D'Ippolito, Lund University., Sharifloo, Amir, Molzam, Hempel, Andreas Berndt, Klein, Cristian, Alessandro Vittorio Papadopoulos, Maggio, Martina,, Vogel, Thomas, Antonio Filieri, Martina Maggio, Sharifloo, Amir,, D Ippolito, N, Gerostathopoulos, I, Jamshidi, P, Misailovic, Sasa, Stepan Shevtsov, Kalyvianaki, Evangelia, Angelopoulos, K, Klein, C, Krikava, F, Suprio Ray, Ray, S, Ro Vittorio Papadopoulos, Papadopoulos, AV, Papadopoulos, Alessandro ,, Papadopoulos, Alessandro Vittorio, Amir M Sharifloo, Gerostathopoulos, Ilias, Konstantinos Angelopoulos, Filieri, A, Shevtsov, S, Mateusz Ujma, Papadopoulos, Alessandro, Vittorio, Ujma, Mateusz   +66 more
core   +1 more source

Enhanced PI control and adaptive gain tuning schemes for distributed secondary control of an islanded microgrid

IET Renewable Power Generation, 2021
This paper develops an enhanced proportional‐integral distributed control scheme (EPI‐DCS) to regulate the frequency and voltage of a droop‐controlled microgrid and share the power mismatch, simultaneously.
Yuanshi Zhang, Amin Mohammadpour Shotorbani, Liwei Wang, Behnam Mohammadi‐Ivatloo   +3 more
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source