Results 61 to 70 of about 1,043,424 (294)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Robust iterative learning control for uncertain continuous‐time system with input delay and random iteration‐varying uncertainties

open access: yesIET Control Theory & Applications, 2021
This study deals with the problem of robust iterative learning control (ILC) for linear continuous‐time systems with input delay subject to uncertainties in input delay, plant dynamic, reference trajectory, initial conditions and disturbances.
Hamid Shokri‐Ghaleh   +2 more
doaj   +1 more source

Hydrogen-bonded multilayer thin films and capsules based on poly(2-n-propyl-2-oxazoline) and tannic acid : investigation on intermolecular forces, stability, and permeability [PDF]

open access: yes, 2019
In recent years, hydrogen-bonded multilayer thin films and capsules based on neutral and nontoxic building blocks have been receiving interest for the design of stimuli-responsive drug delivery systems and for the preparation of thin-film coatings ...
Hoogenboom, Richard   +5 more
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

A fuzzy adaptive admittance controller for force tracking in an uncertain contact environment

open access: yesIET Control Theory & Applications, 2021
Traditional constant admittance controller (CAC) in uncertain contact environment is highly dependent on environmental location and stiffness, which are always difficult to obtain in most applications. To address this problem, a fuzzy adaptive admittance
Zhisen Li   +4 more
doaj   +1 more source

Mathematical control of complex systems 2013 [PDF]

open access: yes, 2014
Mathematical control of complex systems have already become an ideal research area for control engineers, mathematicians, computer scientists, and biologists to understand, manage, analyze, and interpret functional information/dynamical behaviours from ...
Dong, H   +5 more
core   +4 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Enhanced PI control and adaptive gain tuning schemes for distributed secondary control of an islanded microgrid

open access: yesIET Renewable Power Generation, 2021
This paper develops an enhanced proportional‐integral distributed control scheme (EPI‐DCS) to regulate the frequency and voltage of a droop‐controlled microgrid and share the power mismatch, simultaneously.
Yuanshi Zhang   +3 more
doaj   +1 more source

Conceptualizing Cognitive-Behavioral Therapy as a Supportive-Educative Nursing System for Patients with Insomnia [PDF]

open access: yes, 2016
Difficulty initiating and maintaining sleep is one of the most common health complaints of the general population. Approximately 35-50% of people experience occasional insomnia symptoms (Walsh et al., 2011) while 12-20% have insomnia disorder (Morin, et ...
Kurtz, Christine, Schmidt, Nola
core   +2 more sources

Giant Kerr nonlinearities in Circuit-QED [PDF]

open access: yes, 2009
The very small size of optical nonlinearities places wide ranging restrictions on the types of novel physics one can explore. For an ensemble of multi-level systems one can synthesize a large effective optical nonlinearity using quantum coherence effects
D. F. Walls   +4 more
core   +2 more sources

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