Results 81 to 90 of about 177,835 (279)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity. [PDF]

, 2017
Peptide-based supramolecular assemblies are a promising class of nanomaterials with important biomedical applications, specifically in drug delivery and tissue regeneration.
Adler-Abramovich, Lihi, Brahmachari, Sayanti, Bychenko, Darya, DeGrado, William F, Gazit, Ehud, Kolusheva, Sofiya, Mensa, Bruk, Schmidt, Nathan W, Schnaider, Lee, Shaham-Niv, Shira, Shimon, Linda JW   +10 more
core   +3 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Self-assembly of electroactive systems: from dimers to supramolecular polymers [PDF]

, 2018
Supramolecular aggregates and polymers are macromolecular entities that grow up by the non-covalent interaction of suitable monomeric units. In the search for new materials for optoelectronic applications through self-assembly, the control over the ...
Orti, Enrique
core  

Toy amphiphiles on the computer: What can we learn from generic models?

, 2009
Generic coarse-grained models are designed such that they are (i) simple and (ii) computationally efficient. They do not aim at representing particular materials, but classes of materials, hence they can offer insight into universal properties of these ...
Bernardes, Bhattacharya, Brannigan, Brannigan, Brannigan, Brannigan, Carmesin, Cooke, Cordomi, de Meyer, de Planque, de Vries, de Vries, Doi, Düchs, Düchs, Farago, Fraaije, Fraaije, Fraser, Fredrickson, Fredrickson, Ganesan, Gennis, Gompper, Grest, Gunn, Guo, Guo, Guo, Guo, Götz, Haas, Haas, Haas, Halley, Harroun, He, He, He, He, Helfand, Helfand, Helfrich, Huang, Israelachvili, Izvekov, Jain, Karaborni, Katsaras, Killian, Komura, Koynova, Koynova, Kranenburg, Kranenburg, Kranenburg, Larson, Larson, Lei, Lenz, Lenz, Li, Lindahl, Linhananta, Loison, Loison, Loison, Marrink, Marsh, Matsen, Matsen, Matsen, Maurits, Maurits, Müller, Müller, Müller-Plathe, Noguchi, Noguchi, Pabst, Pochan, Safran, Schmid, Schmid, Schmid, Schmid, Schmid, Schmid, Schmid, Schmidt, Sengupta, Sevink, Sevink, Sharpe, Shen, Shillcock, Shillcock, Shull, Shull, Smit, Smit, Smith, Soddemann, Soddemann, Stadler, Stadler, Sun, Tardieu, Tenchov, Varandas, Venturoli, Venturoli, von Gottberg, von Gottberg, Wang, Werner, Werner, Werner, West, Wheeler, Whitmore, Yamamoto, Zhang, Zhang   +124 more
core   +1 more source

Self-Assembly and Viscoelastic Properties of Semifluorinated Polyesters

Macromolecular Chemistry and Physics, 2002
The structure and dynamics of polyesters composed from a rigid aromatic backbone and oxyalkylperfluoroalkyl side chains have been studied using differential scanning calorimetry, small- and wide-angle X-ray scattering, pressure-volume-temperature measurements and rheology. The system was found to undergo three phase transitions.
Gottwald, A., Pospiech, D., Jehnichen, D., Haussler, L., Friedel, P., Pionteck, J., Stamm, M., Floudas, G.   +7 more
openaire   +2 more sources

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

High‐Throughput Miniaturized Screening of Nanoparticle Formation via Inkjet Printing [PDF]

, 2018
This is the peer reviewed version of the following article:Ioanna D. Styliari, et al, ‘High‐Throughput Miniaturized Screening of Nanoparticle Formation via Inkjet Printing’, Macromolecular Materials and Engineering, (2018), which has been published in ...
Alexander, Cameron, Alexander, Morgan R., Burley, Jonathan, Cavanagh, Robert, Conte, Claudia, Couturaud, Benoit, Garnett, Martin, Gordhan, Dipak, Hook, Andrew, Huesler, Amanda, Limo, Marion, Nieto-Orellana, Alejandro, Pearce, Amanda, Styliari, Ioanna Danai, Suksiriworapong, Jiraphong, Taresco, Vincenzo, Williams, Phil   +16 more
core   +4 more sources

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source