Results 51 to 60 of about 117,092 (200)

Semaphorin 3A elevates endothelial cell permeability through PP2A inactivation

, 2012
International audienceVE-cadherin-mediated cell-cell junction weakening increases paracellular permeability in response to both angiogenic and inflammatory stimuli.
Dubois, Sonia, Le Guelte, Armelle, Chneiweiss, Herve, Galan-Moya, Eva-Maria, Dwyer, Julie, Auffray, Cedric, Treps, Lucas, Gavard, Julie, Bidere, Nicolas, Hebda, Jagoda K., Kettler, Garance   +10 more
core   +1 more source

Differential expression of the semaphorin 3A pathway in prostatic cancer [PDF]

Histopathology, 2009
Aims:  To analyse the expression pattern of the semaphorin 3A (Sema3A) pathway, including the receptor neuropilin 1 (NRP1) and its ligands the ‘antitumoral’ Sema3A and the ‘protumoral’ vascular endothelial growth factor (VEGF)in prostatic cancer.Methods and results:  tissues were obtained from 120 patients treated by prostatectomy for clinically ...
Mokrane, Yacoub, Alix, Coulon, Olivier, Celhay, Jacques, Irani, Olivier, Cussenot, Gaelle, Fromont   +5 more
openaire   +2 more sources

Immunohistochemical localization of semaphorin 3A in kidney after different treatments.

, 2013
Immunohistochemical localization of semaphorin 3A was carried out as described in Materials and Methods. Immunostaining for semaphorin 3A is seen in thick ascending limb of the loop of Henle and distal tubular epithelial cells. Scale Bar: 100 µM.
Calpurnia Jayakumar (341127), Catherine D. Krawczeski (385223), Punithavathi Ranganathan (385222), Ganesan Ramesh (341131), Prasad Devarajan (38870), Stephen Looney (237505)   +5 more
core   +1 more source

Quantification of serum semaphorin 3A in different forms AKI and diabetes in mouse.

, 2013
Semaphorin 3A was quantified using ELISA kit as described in Methods. A. Circulating levels of semaphorin 3A before and different time after cisplatin administration.
Calpurnia Jayakumar (341127), Catherine D. Krawczeski (385223), Punithavathi Ranganathan (385222), Ganesan Ramesh (341131), Prasad Devarajan (38870), Stephen Looney (237505)   +5 more
core   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Semaphorin-3A as An Immune Modulator Is Suppressed by MicroRNA-145-5p

Cell Journal, 2018
Objective Semaphorin-3A (SEMA3A) and its receptors are found on some immune cells and act as suppressors of immune cells over-activation. Considering the role of SEMA3A and its down-regulation in some autoimmune diseases, as well as our bioinformatics ...
Mahsa Rezaeepoor, Mazdak Ganjalikhani-hakemi, Shima Shapoori, Nahid Eskandari, Mohammadreza Sharifi, Masoud Etemadifar, Marjan Mansourian   +6 more
doaj   +1 more source

Neurodevelopmental Phenotypes and Brain Anomalies in Individuals With Heterozygous SEMA6A Variants

Clinical Genetics, EarlyView.
SEMA6A plays a role in cell migration and axon guidance in the developing central nervous system. Phenotypes seen in eleven individuals heterozygous for SEMA6A variants included developmental delay, intellectual disability, autism/autistic behaviors, behavioral abnormalities, attention disorders, hypotonia, and brain anomalies.
Evan Burchfiel, Xiaonan Zhao, Nichole M. Owen, Tia Gordon, Mahshid S. Azamian, Eric C. Kao, Fan Xia, Xi Luo, Jill A. Rosenfeld, Seema R. Lalani, Allison P. Ortega, Steven B. Bleyl, Florence Petit, Sulekha Rajagopolan, Bénédicte Demeer, Meredith K. Gillespie, Lijia Huang, Matthew Osmond, Kym M. Boycott, Kyra E. Stuurman, Marjon A. van Slegtenhorst, Haley Soller, Céline Jost, Aurore Garde, Hana Safraou, Laurence Faivre, Victor Faundes, Daryl A. Scott   +27 more
wiley   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Regulation of semaphorin 3A expression and excretion after ischemia reperfusion injury of the kidney.

, 2013
A. Western blot analysis of semaphorin 3A excretion in mice urine before (0 hr) and at different time point after reperfusion. A large increase was detected at 6 hr and 24 hr after reperfusion. B.
Calpurnia Jayakumar (341127), Catherine D. Krawczeski (385223), Punithavathi Ranganathan (385222), Ganesan Ramesh (341131), Prasad Devarajan (38870), Stephen Looney (237505)   +5 more
core   +1 more source