Results 31 to 40 of about 117,092 (200)

Semaphorin‑3A alleviates cardiac hypertrophy by regulating autophagy. [PDF]

Exp Ther Med, 2023
Cardiac hypertrophy, characterized by cardiomyocyte enlargement, is an adaptive response of the heart to certain hypertrophic stimuli; however, prolonged hypertrophy results in cardiac dysfunction and can ultimately cause heart failure. The present study evaluated the role of semaphorin-3A (Sema3A), a neurochemical inhibitor, in cardiac hypertrophy ...
Sun Y, Dong J, Chai X, Wang J, Li B, Yang J.   +5 more
europepmc   +3 more sources

Mutational spectrum of semaphorin 3A and semaphorin 3D genes in Spanish Hirschsprung patients. [PDF]

PLoS ONE, 2013
Hirschsprung disease (HSCR, OMIM 142623) is a developmental disorder characterized by the absence of ganglion cells along variable lengths of the distal gastrointestinal tract, which results in tonic contraction of the aganglionic colon segment and ...
Berta Luzón-Toro, Raquel M Fernández, Ana Torroglosa, Juan Carlos de Agustín, Cristina Méndez-Vidal, Dolores Isabel Segura, Guillermo Antiñolo, Salud Borrego   +7 more
doaj   +1 more source

Correlation of peritumoral edema and microvessel density with tissue expression of VEGF, semaphorins 3A and 3C in patients with meningioma

Asian Pacific Journal of Cancer Biology, 2019
Background: Several angiogenic factors correlate with angiogenesis in meningioma while their exact role is yet to be identified. Semaphorins are described with a variety of physiological functions including angiogenesis and migration of neural crest ...
Mahboobeh Razmkhah
doaj   +3 more sources

Semaphorin 3A Levels in Lupus with and without Secondary Antiphospholipid Antibody Syndrome and Renal Involvement

, 2022
© 2021 American Society for Clinical Pathology, 2021. All rights reserved.Objective: The aim of this study is to evaluate semaphorin 3A levels in patients with systemic lupus erythematosus (SLE) with and without renal involvement and secondary ...
Güven, Serdar Can, Apaydln, Hakan, Topçuoǧlu, Canan, Gök, Kevser, Erden, ABDULSAMET, Bayram, Gözde Sevgi Kart, Özdemir, Bahar, Maraş, Yüksel, Bayram, Doǧan, Ateş, Ortaç, Erten, Şükran, Omma, Ahmet, Armaǧan, Berkan, Küçükşahin, Orhan, Karakaş, Özlem   +14 more
core   +1 more source

Semaphorin-3A and urothelial carcinoma [PDF]

Journal of Molecular and Clinical Medicine, 2019
Urothelial cancer (UC) is a common malignancy with unique biology displaying a high tendency to recur despite complete resection of the primary lesion. In approximately 80% of the patients, UC is a non-curable chronic disease, however in the remaining ~20% of patients, the disease can progress and cause death.
Halachmi Sarel, Bahouth Zaher, Rubinstein Jacob, Vadas Zahava   +3 more
openaire   +1 more source

Semaphorin 3A [PDF]

Cell Adhesion & Migration, 2013
Semaphorin 3A (Sema3A) is a protein identified originally as a diffusible axonal chemorepellent. Sema3A has multifunctional roles in embryonic development, immune regulation, vascularization, and oncogenesis. Bone remodeling consists of two phases: the removal of mineralized bone by osteoclasts and the formation of new bone by osteoblasts, and plays an
openaire   +2 more sources

Assessing the itching intensity using visual analogue scales in atopic dermatitis patients against the background of a therapy with calcineurin inhibitors

Vestnik Dermatologii i Venerologii, 2017
Goal. To assess the effect of topical treatment of atopic dermatitis patients with the 0.1% tacrolimus ointment on the itching intensity and skin expression level of growth factor proteins affecting the intensity of cutaneous innervation.
V. V. Chikin, V. A. Smolyannikova, D. V. Proshutinskaya, M. A. Nefedova   +3 more
doaj   +1 more source

Structure of the Plexin Ectodomain Bound by Semaphorin-Mimicking Antibodies. [PDF]

PLoS ONE, 2016
Semaphorin family proteins act on cells to mediate both repulsive and attractive guidance via binding to plexin family receptors, thereby playing fundamental roles in the morphogenesis and homeostasis of various tissues.
Kei Suzuki, Hiroyuki Tsunoda, Ryusuke Omiya, Kyoko Matoba, Takeshi Baba, Sachiyo Suzuki, Hiroaki Segawa, Atsushi Kumanogoh, Kenji Iwasaki, Kunihiro Hattori, Junichi Takagi   +10 more
doaj   +1 more source

Neuropilin-1/GIPC1 signaling regulates α5β1 integrin traffic and function in endothelial cells [PDF]

, 2009
Neuropilin 1 (Nrp1) is a coreceptor for vascular endothelial growth factor A165 (VEGF-A165, VEGF-A164 in mice) and semaphorin 3A (SEMA3A). Nevertheless, <i>Nrp1</i> null embryos display vascular defects that differ from those of mice lacking ...
Caccavari, Francesca, Valdembri, D., Serini, G., Valdembri, Donatella, Caccavari, F., Caswell Patrick T, Anderson, K.I., Humphries, M.J., Patrick T Caswell, Anderson Kurt I, Anderson, Kurt I., Serini, Guido, Caccavari Francesca, Federico Bussolino, Elena Astanina, Valdembri Donatella, König, I., König, Ireen, Astanina, Elena, Schwarz, J.P., Francesca Caccavari, Jim C Norman, Humphries Martin J, Bussolino, F., Schwarz Juliane P, Guido Serini, Serini Guido, König Ireen, Schwarz, Juliane P., Bussolino, Federico, Kurt I Anderson, Humphries, Martin J., Caswell, Patrick T.; id_orcid, Norman, Jim C., Juliane P Schwarz, Astanina Elena, Astanina, E., Bussolino Federico, Norman, J.C., Donatella Valdembri, Caswell, P.T., Ireen König, Norman Jim C, Martin J Humphries   +43 more
core   +1 more source

Publisher Correction: Semaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8⁺ T cells. [PDF]

Nat Commun
Correction to: Nature Communicationshttps://doi.org/10.1038/s41467-024-47424-z, published online 12 April 2024 In this article the title was incorrectly written as ‘Semmaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour ...
Barnkob MB, Michaels YS, André V, Macklin PS, Gileadi U, Valvo S, Rei M, Kulicke C, Chen JL, Jain V, Woodcock VK, Colin-York H, Hadjinicolaou AV, Kong Y, Mayya V, Mazet JM, Mead GJ, Bull JA, Rijal P, Pugh CW, Townsend AR, Gérard A, Olsen LR, Fritzsche M, Fulga TA, Dustin ML, Jones EY, Cerundolo V.   +27 more
europepmc   +2 more sources