Results 11 to 20 of about 8,554 (168)

Semaphorin 3A in Ankylosing Spondylitis

Journal of Microbiology, Immunology and Infection, 2019
Background/Purpose: To determine serum semaphorin 3A (Sema 3A) levels in ankylosing spondylitis (AS). Methods: Serum Sema 3A was measured in 46 AS patients and 30 healthy controls (HCs).
Hsien-Tzung Liao, Yuh-Feng Lin, Chung-Tei Chou, Chang-Youh Tsai   +3 more
doaj   +3 more sources

Semaphorin 3A, A Potential Target for Low Back Pain. [PDF]

Frontiers in Aging Neuroscience, 2015
Low back pain is a common disorder. Pathological innervation and intervertebral disc degeneration are two major factors associated with this disease. Semaphorin 3A, originally known for its potent inhibiting effect on axonal outgrowth, is recently found ...
Pengbin eYin, Houchen eLv, Lihai eZhang, Licheng eZhang, Peifu eTang   +4 more
doaj   +3 more sources

Semaphorin-3A,semaphorin-7Agene single nucleotide polymorphisms, and systemic lupus erythematosus susceptibility

Autoimmunity, 2019
Background: Semaphorin-3A (Sema3A) and Semaphorin-7A (Sema7A) play crucial roles in immune system by inhibiting T cell proliferation and leading to the secretion of pro-inflammatory cytokines.
Wenbiao Hu, Hai-Feng Pan, Jian Cheng
exaly   +2 more sources

The role of semaphorin 3A on chondrogenic differentiation. [PDF]

In Vitro Cell Dev Biol Anim
AbstractOsteoblast-derived semaphorin3A (Sema3A) has been reported to be involved in bone protection, and Sema3A knockout mice have been reported to exhibit chondrodysplasia. From these reports, Sema3A is considered to be involved in chondrogenic differentiation and skeletal formation, but there are many unclear points about its function and mechanism ...
Tsuboi E, Asakawa Y, Hirose N, Yanoshita M, Sumi C, Takano M, Onishi A, Nishiyama S, Kubo N, Kita D, Tanimoto K.   +10 more
europepmc   +3 more sources

Semaphorin 3A in the Immune System: Twenty Years of Study. [PDF]

Biochemistry (Mosc), 2022
Semaphorin 3A is a secreted glycoprotein, which was originally identified as axon guidance factor in the neuronal system, but it also possesses immunoregulatory properties. Here, the effect of semaphorin 3A on T-lymphocytes, myeloid dendritic cells and macrophages is systematically analyzed on the bases of all publications available in the literature ...
Kiseleva EP, Rutto KV.
europepmc   +3 more sources

Semaphorin 3A is a new early diagnostic biomarker of experimental and pediatric acute kidney injury. [PDF]

PLoS ONE, 2013
Semaphorin 3A is a secreted protein that regulates cell motility and attachment in axon guidance, vascular growth, immune cell regulation and tumor progression. However, nothing is known about its role in kidney pathophysiology.
Calpurnia Jayakumar, Punithavathi Ranganathan, Prasad Devarajan, Catherine D Krawczeski, Stephen Looney, Ganesan Ramesh   +5 more
doaj   +1 more source

Activity-induced secretion of semaphorin 3A mediates learning. [PDF]

Eur J Neurosci, 2021
Abstract The semaphorin family is a well‐characterized family of secreted or membrane‐bound proteins that are involved in activity‐independent neurodevelopmental processes, such as axon guidance, cell migration, and immune functions. Although semaphorins have recently been demonstrated to regulate activity‐dependent synaptic scaling ...
Jitsuki-Takahashi A, Jitsuki S, Yamashita N, Kawamura M, Abe M, Sakimura K, Sano A, Nakamura F, Goshima Y, Takahashi T.   +9 more
europepmc   +4 more sources

Netrin-1 and semaphorin 3A predict the development of acute kidney injury in liver transplant patients. [PDF]

PLoS ONE, 2014
Acute kidney injury (AKI) is a serious complication after liver transplantation. Currently there are no validated biomarkers available for early diagnosis of AKI.
Lidia Lewandowska, Joanna Matuszkiewicz-Rowińska, Calpurnia Jayakumar, Urszula Oldakowska-Jedynak, Stephen Looney, Michalina Galas, Małgorzata Dutkiewicz, Marek Krawczyk, Ganesan Ramesh   +8 more
doaj   +1 more source

Semaphorins in Adult Nervous System Plasticity and Disease

Frontiers in Synaptic Neuroscience, 2021
Semaphorins, originally discovered as guidance cues for developing axons, are involved in many processes that shape the nervous system during development, from neuronal proliferation and migration to neuritogenesis and synapse formation.
Daniela Carulli, Daniela Carulli, Fred de Winter, Joost Verhaagen   +3 more
doaj   +1 more source

The Role of Semaphorin 3A in Bone Remodeling [PDF]

Frontiers in Cellular Neuroscience, 2017
Bone remodeling occurs at the bone surface throughout adult life and associates bony quantity and quality. This process is a balance between the osteoblastic bone formation and osteoclastic bone resorption, which cross-talks together. Semaphorin 3A is a membrane-associated secreted protein and regarded as a diffusible axonal chemorepellent, which has ...
Li, Zhenxia, Hao, Jin, Duan, Xin, Wu, Nan, Zhou, Zongke, Yang, Fan, Li, Juan, Zhao, Zhihe, Huang, Shishu   +8 more
openaire   +2 more sources