Semaphorin 3A is a new early diagnostic biomarker of experimental and pediatric acute kidney injury. [PDF]
PLoS ONE, 2013 Semaphorin 3A is a secreted protein that regulates cell motility and attachment in axon guidance, vascular growth, immune cell regulation and tumor progression. However, nothing is known about its role in kidney pathophysiology.
Calpurnia Jayakumar +5 more
doaj +2 more sources
Brazilian Journal of Medical and Biological Research, 2018 Contrast-induced acute kidney injury (CI-AKI) is a serious complication of diagnostic coronary angiograph and percutaneous coronary intervention (PCI).
Li Ning +7 more
doaj +2 more sources
Neural Regeneration Research, 2016 The expression of nerve cell adhesion molecule L1 in the neuronal growth cone of the central nervous system is strongly associated with the direction of growth of the axon, but its role in the regeneration of the peripheral nerve is still unknown.
Qian-ru He +7 more
doaj +2 more sources
Netrin-1 and semaphorin 3A predict the development of acute kidney injury in liver transplant patients. [PDF]
PLoS ONE, 2014 Acute kidney injury (AKI) is a serious complication after liver transplantation. Currently there are no validated biomarkers available for early diagnosis of AKI.
Lidia Lewandowska +8 more
doaj +2 more sources
Structure of the Semaphorin-3A Receptor Binding Module [PDF]
Neuron, 2003 The semaphorins are a large group of extracellular proteins involved in a variety of processes during development, including neuronal migration and axon guidance. Their distinctive feature is a conserved 500 amino acid semaphorin domain, a ligand-receptor interaction module also present in plexins and scatter-factor receptors.
Antipenko, Alexander +10 more
openaire +3 more sources
Bioactive semaphorin 3A promotes sequential formation of sensory nerve and type H vessels during in situ osteogenesis [PDF]
Frontiers in Bioengineering and Biotechnology, 2023 Introduction: Sensory nerves and vessels are critical for skeletal development and regeneration, but crosstalk between neurovascular network and mineralization are not clear.
Xiaoxiao Han +8 more
doaj +2 more sources
Semaphorin 3A regulates alveolar bone remodeling on orthodontic tooth movement [PDF]
Scientific Reports, 2022 Semaphorin 3A (Sema3A) promotes osteoblast differentiation and inhibits osteoclast differentiation. In the present study, we observed the regulation of alveolar bone remodeling by Sema3A during orthodontic tooth movement (OTM).
Hirokazu Kamei +2 more
doaj +2 more sources
Cdc42 and RhoA reveal different spatio-temporal dynamics upon local stimulation with Semaphorin-3A [PDF]
Frontiers in Cellular Neuroscience, 2015 Small RhoGTPases, such as Cdc42 and RhoA, are key players in integrating external cues and intracellular signaling pathways that regulate growth cone (GC) motility.
Federico eIseppon +4 more
doaj +2 more sources
Activity-induced secretion of semaphorin 3A mediates learning. [PDF]
Eur J Neurosci, 2021 Abstract The semaphorin family is a well‐characterized family of secreted or membrane‐bound proteins that are involved in activity‐independent neurodevelopmental processes, such as axon guidance, cell migration, and immune functions. Although semaphorins have recently been demonstrated to regulate activity‐dependent synaptic scaling ...
Jitsuki-Takahashi A +9 more
europepmc +4 more sources
Mutational spectrum of semaphorin 3A and semaphorin 3D genes in Spanish Hirschsprung patients. [PDF]
PLoS ONE, 2013 Hirschsprung disease (HSCR, OMIM 142623) is a developmental disorder characterized by the absence of ganglion cells along variable lengths of the distal gastrointestinal tract, which results in tonic contraction of the aganglionic colon segment and ...
Berta Luzón-Toro +7 more
doaj +7 more sources