Results 21 to 30 of about 8,560 (166)

The Role of Semaphorin 3A in Bone Remodeling [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2017
Bone remodeling occurs at the bone surface throughout adult life and associates bony quantity and quality. This process is a balance between the osteoblastic bone formation and osteoclastic bone resorption, which cross-talks together. Semaphorin 3A is a membrane-associated secreted protein and regarded as a diffusible axonal chemorepellent, which has ...
Li, Zhenxia   +8 more
openaire   +2 more sources

Urinary semaphorin 3A as an early biomarker to predict contrast-induced acute kidney injury in patients undergoing percutaneous coronary intervention

open access: yesBrazilian Journal of Medical and Biological Research, 2018
Contrast-induced acute kidney injury (CI-AKI) is a serious complication of diagnostic coronary angiograph and percutaneous coronary intervention (PCI).
Li Ning   +7 more
doaj   +1 more source

Inhibition of CNS Remyelination by the Presence of Semaphorin 3A [PDF]

open access: yesThe Journal of Neuroscience, 2011
Failure of oligodendrocyte precursor cell (OPC) differentiation has been recognized as the leading cause for the failure of myelin regeneration in diseases such as multiple sclerosis (MS). One explanation for the failure of OPC differentiation in MS is the presence of inhibitory molecules in demyelinated lesions. So far only a few inhibitory substrates
Syed, Y.   +6 more
openaire   +5 more sources

Correlation of peritumoral edema and microvessel density with tissue expression of VEGF, semaphorins 3A and 3C in patients with meningioma

open access: yesAsian Pacific Journal of Cancer Biology, 2019
Background: Several angiogenic factors correlate with angiogenesis in meningioma while their exact role is yet to be identified. Semaphorins are described with a variety of physiological functions including angiogenesis and migration of neural crest ...
Mahboobeh Razmkhah
doaj   +3 more sources

Semaphorin-3A and urothelial carcinoma [PDF]

open access: yesJournal of Molecular and Clinical Medicine, 2019
Urothelial cancer (UC) is a common malignancy with unique biology displaying a high tendency to recur despite complete resection of the primary lesion. In approximately 80% of the patients, UC is a non-curable chronic disease, however in the remaining ~20% of patients, the disease can progress and cause death.
Halachmi Sarel   +3 more
openaire   +1 more source

Expression changes of nerve cell adhesion molecules L1 and semaphorin 3A after peripheral nerve injury

open access: yesNeural Regeneration Research, 2016
The expression of nerve cell adhesion molecule L1 in the neuronal growth cone of the central nervous system is strongly associated with the direction of growth of the axon, but its role in the regeneration of the peripheral nerve is still unknown.
Qian-ru He   +7 more
doaj   +1 more source

Semaphorin 3A [PDF]

open access: yesCell Adhesion & Migration, 2013
Semaphorin 3A (Sema3A) is a protein identified originally as a diffusible axonal chemorepellent. Sema3A has multifunctional roles in embryonic development, immune regulation, vascularization, and oncogenesis. Bone remodeling consists of two phases: the removal of mineralized bone by osteoclasts and the formation of new bone by osteoblasts, and plays an
openaire   +2 more sources

Assessing the itching intensity using visual analogue scales in atopic dermatitis patients against the background of a therapy with calcineurin inhibitors

open access: yesVestnik Dermatologii i Venerologii, 2017
Goal. To assess the effect of topical treatment of atopic dermatitis patients with the 0.1% tacrolimus ointment on the itching intensity and skin expression level of growth factor proteins affecting the intensity of cutaneous innervation.
V. V. Chikin   +3 more
doaj   +1 more source

Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea. [PDF]

open access: yesPLoS Genetics, 2017
Neuropilin-1 (Nrp1) encodes the transmembrane cellular receptor neuropilin-1, which is associated with cardiovascular and neuronal development and was within the peak SNP interval on chromosome 8 in our prior GWAS study on age-related hearing loss (ARHL)
Pezhman Salehi   +15 more
doaj   +1 more source

Cdc42 and RhoA reveal different spatio-temporal dynamics upon local stimulation with Semaphorin-3A

open access: yesFrontiers in Cellular Neuroscience, 2015
Small RhoGTPases, such as Cdc42 and RhoA, are key players in integrating external cues and intracellular signaling pathways that regulate growth cone (GC) motility.
Federico eIseppon   +4 more
doaj   +1 more source

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