Results 51 to 60 of about 9,419 (207)

Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds

open access: yesChemMedChem, Volume 21, Issue 2, January 2026.
Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley   +1 more source

Nitrofuran antibiotics: a review on the application, prohibition and residual analysis

open access: yesVeterinární Medicína, 2008
Nitrofuran antibiotics, employed for the treatment of bacterial diseases in livestock production, were banned from use in the European Union (EU) in 1995 due to concerns about the carcinogenicity of their residues in edible tissue.
M. Vass, K. Hruska, M. Franek
doaj   +1 more source

Carboxyl Group-Modified Myoglobin Induces TNF-α-Mediated Apoptosis in Leukemia Cells

open access: yesPharmaceuticals, 2022
Previous studies have shown that chemical modification may increase the activity of proteins or confer novel activity to proteins. Some studies have indicated that myoglobin (Mb) is cytotoxic; however, the underlying mechanisms remain unclear.
Yuan-Chin Lee   +5 more
doaj   +1 more source

Enhancing Open‐Circuit Voltage and Fill Factor in Sn‐Based Perovskite Solar Cells: Challenges and Opportunities for Sustainable Photovoltaics

open access: yesSusMat, Volume 5, Issue 6, December 2025.
This review summarizes advances in tin (Sn)‐based perovskite solar cells, a promising lead‐free alternative. It examines the main causes of Voc and fill factor losses, including Sn2+ oxidation, undercoordinated sites, and deep‐level traps. Strategies such as molecular coordination, surface passivation, compositional tuning, interface engineering, and ...
Padmini Pandey   +4 more
wiley   +1 more source

Synthesis, characterization, antimicrobial, and pharmacological evaluation of some 2, 5-disubstituted sulfonyl amino 1,3,4-oxadiazole and 2-amino-disubstituted 1,3,4-thiadiazole derivatives

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2014
The presence of heterocyclic structures in diverse types of compounds, this is strongly indicative of the profound effect like structure exerts on physiologic activity, and recognition of this is abundantly reflected in efforts to find useful synthetic ...
Dilipkumar Pal   +3 more
doaj   +1 more source

Examination of the Potential for Adaptive Chirality of the Nitrogen Chiral Center in Aza-Aspartame

open access: yesMolecules, 2013
The potential for dynamic chirality of an azapeptide nitrogen was examined by substitution of nitrogen for the α-carbon of the aspartate residue in the sweetener S,S-aspartame.
Samir H. Bouayad-Gervais   +1 more
doaj   +1 more source

Semicarbazide-sensitive amine oxidase (SSAO): from cell to circulation [PDF]

open access: yes, 2005
Semicarbazide-sensitive amine oxidase (SSAO) is a multi-functional enzyme widely present in nature. It converts primary amines into their corresponding aldehydes, while generating H(2)O(2) and NH(3).
Bagghoe, U.   +3 more
core  

Hypothalamic Astrocytes Exhibit Glycolytic Features Making Them Prone for Glucose Sensing

open access: yesGlia, Volume 73, Issue 11, Page 2253-2272, November 2025.
Main Points Hypothalamic astrocytes versus cortical astrocytes: are more glycolytic due to high Pkm2, Glut1 and Mct4 expression do not exhibit glutamate‐induced glycolysis detect glucose concentration variations via an AMPK sensor with altered lactate production.
Sarah Geller   +11 more
wiley   +1 more source

Development of biomimetic enzyme-linked immunosorbent assay based on molecular imprinting technique for semicarbazide detection

open access: yesFood and Agricultural Immunology, 2020
Herein, we present a direct competitive biomimetic enzyme-linked immunosorbent assay (BELISA) method for the determination of semicarbazide (SEM) using a molecularly imprinted polymer (MIP) film as the bionic antibody. The best monomer (methacrylic acid)
Wenlong Yu   +5 more
doaj   +1 more source

Genomewide and Enzymatic Analysis Reveals Efficient d-Galacturonic Acid Metabolism in the Basidiomycete Yeast Rhodosporidium toruloides. [PDF]

open access: yes, 2019
Biorefining of renewable feedstocks is one of the most promising routes to replace fossil-based products. Since many common fermentation hosts, such as Saccharomyces cerevisiae, are naturally unable to convert many component plant cell wall ...
Arkin, Adam P   +10 more
core   +1 more source

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