Results 1 to 10 of about 33,270 (306)

Integrated Molecular Analysis Reveals 2 Distinct Subtypes of Pure Seminoma of the Testis

open access: yesCancer Informatics, 2022
Objective: Testicular germ cell tumors (TGCT) are the most common solid malignancy in adolescent and young men, with a rising incidence over the past 20 years.
Kirill E Medvedev   +5 more
doaj   +2 more sources

Cisplatin-based chemotherapy of testicular cancer - Two decades after a major breakthrough [PDF]

open access: yes, 2000
Two decades ago the introduction of cisplatin-based combination chemotherapy has dramatically improved the prognosis of patients with metastatic testicular cancer, At present 3 cycles of cisplatin, etoposide and bleomycin are considered as standard ...
Gerl, Arthur
core   +1 more source

Development of CNS-type Primitive Neuroectodermal Tumor in Metastatic Testicular Mixed Germ Cell Tumor. [PDF]

open access: yes, 2016
A 29-year-old man presenting with a retroperitoneal mass was found to have a testis lesion consistent with mixed germ cell tumor and the RPLND specimen showed teratoma with an area of central nervous system-type primitive neuroectodermal tumor (PNET) not
Meng, Maxwell V   +2 more
core   +2 more sources

Seminoma in a Man with Russell-Silver Syndrome Presenting with Testicular Torsion

open access: yesCase Reports in Urology, 2016
Russell-Silver syndrome (RSS) is a type of primordial dwarfism. Only one case of testicular cancer in RSS has been reported, the pathology of which was nonseminoma.
Satoshi Funada   +3 more
doaj   +1 more source

Surgical salvage in patients with advanced testicular cancer: indications, risks and outcomes [PDF]

open access: yes, 2020
The purpose of this review is to present a comprehensive and updated review of the literature and summary of the indications, risks and outcomes related to salvage, desperation and late relapse surgery for advanced testicular cancer.
Cary, Clint   +2 more
core   +1 more source

Metastatic Seminoma with Positive Staining of Cytokeratin and MOC31: A Diagnostic Pitfall

open access: yesCase Reports in Pathology, 2021
Retroperitoneal metastasis of seminoma often occurs in the higher stage through lymph nodes. Generally, seminoma expresses specific germ cell markers while being negative for carcinoma markers.
Jiaming Fan   +3 more
doaj   +1 more source

Fatherhood and sperm DNA damage in testicular cancer patients [PDF]

open access: yes, 2018
Testicular cancer (TC) is one of the most treatable of all malignancies and the management of the quality of life of these patients is increasingly important, especially with regard to their sexuality and fertility.
Lenzi, Andrea   +3 more
core   +1 more source

Primary seminoma of prostate in a patient with Klinefelter syndrome

open access: yesMedicine, 2022
. Rationale:. Klinefelter syndrome (KS) is a sex differentiation syndrome that occurs in men and is characterized by the 47XXY genotype. An association between KS and cancer has also been reported. The occurrence of seminoma of the prostate in KS has not
Duncheng Shi, MD   +6 more
doaj   +1 more source

PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation. [PDF]

open access: yes, 2018
Germ cell tumors (GCTs) are a heterogeneous group of tumors occurring in gonadal and extragonadal locations. GCTs are hypothesized to arise from primordial germ cells (PGCs), which fail to differentiate.
Chen, Di   +4 more
core   +2 more sources

Testicular Seminoma With Pseudocyst and Coagulation Necrosis Like Burned-out Tumor: A Case Report

open access: yesUrology Case Reports, 2016
Testicular seminoma is a relatively common testicular cancer; however, testicular seminoma with pseudocyst is an extremely rare. The ‘burned-out’ phenomenon in germ cell tumors refers to a germ cell tumor in extra-gonadal tissues with spontaneous ...
Tatsuhiko Hoshii   +3 more
doaj   +1 more source

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