Results 1 to 10 of about 17,398 (195)

Mutations in LRRC50 predispose zebrafish and humans to seminomas. [PDF]

PLoS Genetics, 2013
Seminoma is a subclass of human testicular germ cell tumors (TGCT), the most frequently observed cancer in young men with a rising incidence. Here we describe the identification of a novel gene predisposing specifically to seminoma formation in a ...
Sander G Basten, Erica E Davis, Ad J M Gillis, Ellen van Rooijen, Hans Stoop, Nikolina Babala, Ive Logister, Zachary G Heath, Trudy N Jonges, Nicholas Katsanis, Emile E Voest, Freek J van Eeden, Rene H Medema, René F Ketting, Stefan Schulte-Merker, Leendert H J Looijenga, Rachel H Giles   +16 more
doaj   +9 more sources

Semen quality from patients affected by seminomatous and non-seminomatous testicular tumor [PDF]

International Brazilian Journal of Urology, 2021
Testicular cancer is considered a rare disease affecting approximately 1% to 2% of the male population. This neoplasm has a cure rate of over 95%; as a result, a major concern is the future of fertility of carriers from this disease.
Rosana Xavier, Renata Cristina de Carvalho, Renato Fraietta   +2 more
doaj   +1 more source

Hypothesis: when is a seminoma not a seminoma? [PDF]

Journal of Clinical Pathology, 1981
A xenograft line, HX 53, has been established in immune-suppressed mice from a specimen of a lymph node metastasis in a patient with a histological diagnosis of seminoma but with markedly raised circulating levels of alpha-fetoprotein. Histological, immunocytochemical, and ultrastructural studies of this xenograft line have suggested that a solid ...
A M Neville, E Heyderman, D Raghavan, M J Peckham, E Ruoslahti, J Gibbs, P Monaghan   +6 more
openaire   +6 more sources

5-YEAR RELATIVE SURVIVAL RATE BETWEEN SEMINOMA AND NON-SEMINOMA TESTICULAR CANCER IN SINGLE CENTER

Jurnal Urologi Indonesia, 2023
Objective: This study was conducted to provide data about the survival rate of testicular cancer patients with different histology in the year 2013 – 2017 in Adam Malik General Hospital and to compare these estimates with other studies conducted in ...
Ben Julian Mantiri, Ginanda Putra Siregar, Syah Mirsya Warli   +2 more
doaj   +1 more source

Clinico-epidemiological Profile and Outcome of Testicular Germ Cell Tumors: A Retrospective Study from a Tertiary Cancer Centre of North-East India

Asian Pacific Journal of Cancer Care, 2023
Introduction: Testicular Germ Cell Tumor (GCT) is a disease of young adults and is also highly curable. But in India, most of the patients present in an advanced stage and succumb to the disease as compared to the Western nations where patients present ...
Amritjot Singh Randhawa, Manas Dubey, Partha Sarathi Roy, Munlima Hazarika, Duncan Khanikar   +4 more
doaj   +1 more source

Metástase de seminoma em região orbital em cão - relato de caso [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2020
RESUMO O seminoma é uma neoformação testicular originária de células germinativas de ocorrência comum em cães, com maior prevalência em animais senis. Em geral, o comportamento biológico do seminoma canino é benigno.
S.L. Dias, L.R. Moroz, D.F.R.P. Souza, L.O. Simões, T.C. Peixoto, C.G. Pires   +5 more
doaj   +1 more source

Single-cell multi-omics analysis of human testicular germ cell tumor reveals its molecular features and microenvironment

Nature Communications, 2023
Seminoma is the most common malignant solid tumor in 14 to 44 year-old men. However, its molecular features and tumor microenvironment (TME) is largely unexplored.
Xiaojian Lu, Yanwei Luo, Xichen Nie, Bailing Zhang, Xiaoyan Wang, Ran Li, Guangmin Liu, Qianyin Zhou, Zhizhong Liu, Liqing Fan, James M. Hotaling, Zhe Zhang, Hao Bo, Jingtao Guo   +13 more
doaj   +1 more source

CHARACTERISTIC CHEMOTHERAPY RESPONSE OF TESTICULAR CANCER PATIENTS IN TERTIARY HOSPITAL

Jurnal Urologi Indonesia, 2022
Objective: The purpose of this study was to determine the correlation of testicular tumor markers on the success of chemotherapy in my institution.
Dio Mafazi Fabrianta, Kurnia Penta Seputra, Besut Daryanto   +2 more
doaj   +1 more source

CDKN2AIP-induced cell senescence and apoptosis of testicular seminoma are associated with CARM1 and eIF4β

Acta Biochimica et Biophysica Sinica, 2022
Testicular seminoma is a relatively rare tumor which is mostly detected in male population aged from 15 to 35 years old. Although several molecular biomarkers have been identified to be associated with testicular seminoma pathogenesis, the exact ...
Cao Yuming, Chen Zhenlie, Qin Zihan, Qian Kaiyu, Liu Tongzu, Zhang Yuanzhen   +5 more
doaj   +1 more source

Single-Cell RNA Sequencing of Metastatic Testicular Seminoma Reveals the Cellular and Molecular Characteristics of Metastatic Cell Lineage

Frontiers in Oncology, 2022
BackgroundTesticular cancer is the most common solid malignancy in young men. Given the many histological classifications of testicular tumors, seminoma is one of the most treatable cancers.
Linjian Mo, Linjian Mo, Zhenyuan Yu, Zhenyuan Yu, Yufang Lv, Yufang Lv, Jiwen Cheng, Haibiao Yan, Wenhao Lu, Wenhao Lu, Cheng Su, Cheng Su, Qiang Ling, Qiang Ling, Zengnan Mo, Zengnan Mo   +15 more
doaj   +1 more source