Integrated Molecular Analysis Reveals 2 Distinct Subtypes of Pure Seminoma of the Testis
Objective: Testicular germ cell tumors (TGCT) are the most common solid malignancy in adolescent and young men, with a rising incidence over the past 20 years.
Kirill E Medvedev+5 more
doaj +1 more source
Development of CNS-type Primitive Neuroectodermal Tumor in Metastatic Testicular Mixed Germ Cell Tumor. [PDF]
A 29-year-old man presenting with a retroperitoneal mass was found to have a testis lesion consistent with mixed germ cell tumor and the RPLND specimen showed teratoma with an area of central nervous system-type primitive neuroectodermal tumor (PNET) not
Meng, Maxwell V+2 more
core +2 more sources
Seminoma in a Man with Russell-Silver Syndrome Presenting with Testicular Torsion
Russell-Silver syndrome (RSS) is a type of primordial dwarfism. Only one case of testicular cancer in RSS has been reported, the pathology of which was nonseminoma.
Satoshi Funada+3 more
doaj +1 more source
Surgical salvage in patients with advanced testicular cancer: indications, risks and outcomes [PDF]
The purpose of this review is to present a comprehensive and updated review of the literature and summary of the indications, risks and outcomes related to salvage, desperation and late relapse surgery for advanced testicular cancer.
Cary, Clint+2 more
core +1 more source
Types of testicular tumors in Shahid Beheshti Hospital of Babol, Iran, during 2001‒2021 [PDF]
Background. Testicular tumors account for about 1% of all male cancers. Considering that there is no accurate information about the prevalence of testicular tumors in Iran, this study aimed to investigate the types of testicular tumors in the hospitals ...
Sorena Samimi+2 more
doaj +1 more source
Two decades of FDG-PET/CT in seminoma: exploring its role in diagnosis, surveillance and follow-up
Background Survivors of testicular cancer may experience long-term morbidity following treatment. There is an unmet need to investigate techniques that can differentiate individuals who need additional therapy from those who do not.
Ciara Conduit+8 more
doaj +1 more source
Treatment of CD30-Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases [PDF]
BACKGROUND: Cytotoxic therapy for relapsed and refractory germ cell tumors or metastatic sex cord stromal tumors is rarely effective and is often accompanied by high adverse event rates.
Albany, Costantine+5 more
core +1 more source
PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation. [PDF]
Germ cell tumors (GCTs) are a heterogeneous group of tumors occurring in gonadal and extragonadal locations. GCTs are hypothesized to arise from primordial germ cells (PGCs), which fail to differentiate.
Chen, Di+4 more
core +2 more sources
Spermatocytic Seminoma is an unusual germ cell tumour known to arise from testis only. It is associated with good prognosis. Testicular tumours as such are uncommon in Asia as compared to western countries.
Sanjay N Koppad+4 more
doaj +1 more source
Morphological and immunohistochemical characterisation of seminomas in Norwegian dogs
Background Seminomas in the dog have traditionally been assumed to resemble human spermatocytic seminomas, based on their low malignancy and high occurrence in old individuals.
Thorvaldsen Tor+3 more
doaj +1 more source