Results 31 to 40 of about 25,171 (251)

Molecular pathology of testicular germ cell tumours: an update for practicing pathologists. [PDF]

Histopathology
Molecular testing for isochromosome 12p is usually only necessary in difficult cases that encompass metastases or recurrent diseases including somatic‐type malignancies. So far, no breaking progress has been made in the field of targeted therapy as TGCTs only rarely show targetable molecular alterations.
Fichtner A, Zschäbitz S, Nettersheim D, Bremmer F.   +3 more
europepmc   +2 more sources

PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation. [PDF]

, 2018
Germ cell tumors (GCTs) are a heterogeneous group of tumors occurring in gonadal and extragonadal locations. GCTs are hypothesized to arise from primordial germ cells (PGCs), which fail to differentiate.
Chen, Di, Clark, Amander T, Gell, Joanna J, Hunt, Timothy J, Zhao, Jasmine   +4 more
core   +2 more sources

Integrated Molecular Analysis Reveals 2 Distinct Subtypes of Pure Seminoma of the Testis

Cancer Informatics, 2022
Objective: Testicular germ cell tumors (TGCT) are the most common solid malignancy in adolescent and young men, with a rising incidence over the past 20 years.
Kirill E Medvedev, Anna V Savelyeva, Kenneth S Chen, Aditya Bagrodia, Liwei Jia, Nick V Grishin   +5 more
doaj   +1 more source

A population-based case-control study on social factors and risk of testicular germ cell tumours [PDF]

, 2013
Objectives Incidence rates for testicular cancer have risen over the last few decades. Findings of an association between the risk of testicular cancer and social factors are controversial. The association of testicular cancer and different indicators of
Ahrens, W., Baumgardt-Elms, C., Behrens, T., Conway, D.I., Jahn, I., Jockel, K.-H., Schmeisser, N., Stang, A., Stegmaier, C.   +8 more
core   +1 more source

Nuclear medicine procedures and the evaluation of male sexual organs: a short review [PDF]

, 2008
Sexuality consists of three aspects that are interrelated and inseparable, biological, physiological and social. The biological aspect considers the individual's capability to give and to receive pleasure.
Adenilson de Souza da Fonseca, Bernardo-Filho M., Beutel M. E., Bouchelouche K., Chaffanjon P. C., Choe W., Dennerstein L., Fanti S., Ganjoo K. N., Gerber G., Halac M., Hatzimouratidis H., Jana S., Kevin Carter, Kim C. K., Kolodny R. C., Kotzerke J., Kotzerke J., Kumar V., Lange P. H., Mario Bernardo-Filho, Masters W. H., Orhan I., Perkins A., Perkins A., Ravizzini G., Roivainen A., Ryu J., Saha G., Sebastião David Santos-Filho, Shen Y. Y., Sotiris Missailidis, Stelzner F., Sumich A. L., Timmermans L., Tóth G., Valdés Olmos R. A., Warren G. P., Willan B. D., Zuckier L. S.   +39 more
core   +4 more sources

Fatherhood and sperm DNA damage in testicular cancer patients [PDF]

, 2018
Testicular cancer (TC) is one of the most treatable of all malignancies and the management of the quality of life of these patients is increasingly important, especially with regard to their sexuality and fertility.
Lenzi, Andrea, Lombardo, Francesco, Pallotti, Francesco, Paoli, Donatella   +3 more
core   +1 more source

Two decades of FDG-PET/CT in seminoma: exploring its role in diagnosis, surveillance and follow-up

Cancer Imaging, 2022
Background Survivors of testicular cancer may experience long-term morbidity following treatment. There is an unmet need to investigate techniques that can differentiate individuals who need additional therapy from those who do not.
Ciara Conduit, Thuan Tzen Koh, Michael S Hofman, Guy C Toner, Jeremy Goad, Nathan Lawrentschuk, Keen-Hun Tai, Jeremy H Lewin, Ben Tran   +8 more
doaj   +1 more source

Primary seminoma of prostate in a patient with Klinefelter syndrome

Medicine, 2022
. Rationale:. Klinefelter syndrome (KS) is a sex differentiation syndrome that occurs in men and is characterized by the 47XXY genotype. An association between KS and cancer has also been reported. The occurrence of seminoma of the prostate in KS has not
Duncheng Shi, MD, Changjian Chen, MD, Huagang Huang, MD, Jingyu Tian, MD, Jianfang Zhou, MD, Shihua Jin, MD, Maya Saranathan.   +6 more
doaj   +1 more source

Testicular cancer and sperm DNA damage: short- and long-term effects of antineoplastic treatment [PDF]

, 2015
The aim of this study was to investigate sperm DNA damage induced by chemo- and radiotherapy in patients with testicular cancer to provide data on the extent and persistence of nuclear damage that might affect individual reproductive potential.
F. Rizzo, G. Leter, GALLO, MARIAGRAZIA, GANDINI, Loredana, LENZI, Andrea, LOMBARDO, Francesco, M. Spano, PAOLI, Donatella   +7 more
core   +1 more source

Seminoma in a Man with Russell-Silver Syndrome Presenting with Testicular Torsion

Case Reports in Urology, 2016
Russell-Silver syndrome (RSS) is a type of primordial dwarfism. Only one case of testicular cancer in RSS has been reported, the pathology of which was nonseminoma.
Satoshi Funada, Ryosuke Ikeuchi, Toru Yoshida, Takehiko Segawa   +3 more
doaj   +1 more source