Results 81 to 90 of about 4,361,080 (379)

Joint modeling of sensitivity and specificity [PDF]

Statistics in Medicine, 2008
AbstractSensitivity and specificity are two customary performance measures associated with medical diagnostic tests. Typically, they are modeled independently as a function of risk factors using logistic regression, which provides estimated functions for these probabilities.
Puggioni, Gavino, Gelfand, Alan E., Elmore, Joann G.   +2 more
openaire   +4 more sources

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

FEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva, Marcio Vinicius Bertacine Dias   +1 more
wiley   +1 more source

Comparison of rapid laboratory tests for failure of passive transfer in the bovine [PDF]

, 2015
peer-reviewedBackground Failure of passive transfer of maternal immunity via colostrum can occur in the bovine, and a number of blood tests have been developed to test calves for this failure. It is not clear which test is most suitable for this purpose.
Brady, Paula, Conneely, Muireann, Doherty, Michael L., Fagan, John, Hogan, Ian, Kennedy, Emer, Lorenz, Ingrid, Ryan, Clare   +7 more
core   +1 more source

Psychometric Properties of Persian Version of Checklist for Autism in Toddlers (CHAT)

مجله دانشکده پزشکی اصفهان, 2019
Background: The increasing rate of autism spectrum disorder highlights the need for early screening with the aim to provide early intervention. This study aimed to provide Persian version of Checklist for Autism in Toddlers (CHAT) and assess its ...
Amrollah Ebrahimi, Fereshteh Shakibaei, Ali Reza Mohseni, Zahra Khayyer, Elnaz Pishghadam, Hamid Nasiri-Dehsorkhi   +5 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Part 1: Simple Definition and Calculation of Accuracy, Sensitivity and Specificity

Archives of Academic Emergency Medicine, 2018
Emergency physicians, like other specialists, are faced with different patients and various situations each day. They have to use ancillary diagnostic tools like laboratory tests and imaging studies to be able to manage them.
Alireza Baratloo, Mostafa Hosseini, Ahmed Negida, Gehad El Ashal   +3 more
doaj   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Sensitivity and specificity of detection methods for erythropoietin doping in cyclists [PDF]

, 2019
Recombinant human erythropoietin (rHuEPO) is used as doping a substance. Anti-doping efforts include urine and blood testing and monitoring the athlete biological passport (ABP).
Burggraaf, Jacobus, Cohen, Adam F, Daniels, Johannes MA, Gal, Pim, Heuberger, Jules AAC, Hon, Olivier, Post, Titiaan E, Ram, Herman, Rotmans, Joris I, Stuurman, Frederik E, Van Eenoo, Peter   +10 more
core   +1 more source

Clinical and laboratory signs associated to serious dengue disease in hospitalized children

Jornal de Pediatria (Versão em Português), 2016
Objective: To evaluate the validity of clinical and laboratory signs to serious dengue disease in hospitalized children. Methods: Retrospective cohort of children (19 and negative likelihood ratio
Sheila Moura Pone, Yara Hahr Marques Hökerberg, Raquel de Vasconcellos Carvalhaes de Oliveira, Regina Paiva Daumas, Tamiris Moura Pone, Marcos Vinicius da Silva Pone, Patricia Brasil   +6 more
doaj   +1 more source

Canine Olfactory Differentiation of Cancer: A Review of the Literature [PDF]

arXiv, 2015
Numerous studies have attempted to demonstrate the olfactory ability of canines to detect several common cancer types from human bodily fluids, breath and tissue. Canines have been reported to detect bladder cancer (sensitivity of 0.63-0.73 and specificity of 0.64-0.92) and prostate cancer (sensitivity of 0.91-0.99 and specificity of 0.91-0.97) from ...
arxiv