Results 51 to 60 of about 103,787 (262)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Sensor Selection for an Electronic Tongue for the Rapid Detection of Paralytic Shellfish Toxins: A Case Study

open access: yesChemosensors
The performance of an electronic tongue can be optimized by varying the number and types of sensors in the array and by employing data-processing methods.
Mariana Raposo   +4 more
doaj   +1 more source

Adaptive Sensor Array Error Calibration Based Impact Localization on Composite Structure

open access: yesApplied Sciences, 2020
Gains and phases delay induced by sensor position error would significantly degrade the performance of high-resolution two-dimensional multiple signal classification (2D-MUSIC) algorithm, which resulting in low positioning estimation accuracy and poor ...
Li Ren   +3 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Thermos Array: Two-Dimensional Sparse Array with Reduced Mutual Coupling

open access: yesInternational Journal of Antennas and Propagation, 2018
Sparse planar arrays, such as the billboard array, the open box array, and the two-dimensional nested array, have drawn lots of interest owing to their ability of two-dimensional angle estimation.
Lei Sun, Minglei Yang, Baixiao Chen
doaj   +1 more source

Sensor Array Based on Molecularly Imprinted Polymers for Simultaneous Detection of Lipoproteins

open access: yesProceedings, 2017
Herein we report a sensor array based on quartz crystal microbalance (QCM) to simultaneously detect two biomarkers, namely low-density lipoprotein (LDL), and high-density lipoprotein (HDL).
Suticha Chunta   +3 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Intelligent Fusion Method Based on BP Neural Network for Robot Suit Pressure Sensing Array Data [PDF]

open access: yesInternational Journal Bioautomation, 2017
In order to eliminate the crosstalk influence existed among temperature, voltage fluctuation and sensor signal of robot tactile sensor array unit, the paper presented a sort of information fusion method in large scale sensor array based on BP neural ...
Bing Guo, Xinli Deng
doaj  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

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