Results 41 to 50 of about 108,556 (263)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Design of a Capacitive Tactile Sensor Array System for Human–Computer Interaction

open access: yesSensors
This paper introduces a novel capacitive sensor array designed for tactile perception applications. Utilizing an all-in-one inkjet deposition printing process, the sensor array exhibited exceptional flexibility and accuracy. With a resolution of up to 32.
Fei Fei   +4 more
doaj   +1 more source

Wireless Sensor Array Network DoA Estimation from Compressed Array Data via Joint Sparse Representation

open access: yesSensors, 2016
A compressive sensing joint sparse representation direction of arrival estimation (CSJSR-DoA) approach is proposed for wireless sensor array networks (WSAN).
Kai Yu   +6 more
doaj   +1 more source

An array virtual extension method for power equipment acoustic emission direction of arrival estimation based on high‐order cumulants

open access: yesHigh Voltage, 2021
The performance of array‐based power equipment acoustic emission (AE) source directional of arrival (DOA) estimation methods is decided by not only algorithm performance, but also the array hardware parameters, that is, array aperture, sensor number, and
Nan Zhou   +4 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Development of a Tonometric Sensor with a Decoupled Circular Array for Precisely Measuring Radial Artery Pulse

open access: yesSensors, 2016
The radial artery pulse is one of the major diagnostic indices used clinically in both Eastern and Western medicine. One of the prominent methods for measuring the radial artery pulse is the piezoresistive sensor array. Independence among channels and an
Min-Ho Jun   +5 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Sensor Selection for an Electronic Tongue for the Rapid Detection of Paralytic Shellfish Toxins: A Case Study

open access: yesChemosensors
The performance of an electronic tongue can be optimized by varying the number and types of sensors in the array and by employing data-processing methods.
Mariana Raposo   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy