Results 61 to 70 of about 103,787 (262)

The future of fluorescence sensor arrays

open access: yesTrends in Biotechnology, 2005
The rapid progress in sensor and biosensor array technologies needs a general strategy in the design of fluorescence reporters. Such reporters should provide a high density of sensor elements, allow analysis of targets of different affinities, and be internally calibrated, reproducible and have a rapid readout.
openaire   +4 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Synchronous Reflectivity Measurement of a Weak Fiber Bragg Grating Array Using Frequency-Shifted Interferometry

open access: yesIEEE Photonics Journal, 2018
We demonstrate a method of reflectivity measurement for a weak fiber Bragg grating (FBG) sensor array based on frequency shifted interferometry. In the scheme, the measured weak FBG sensor array was connected after a referenced weak FBG, by using ...
Yiwen Ou   +5 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Two-Dimensional Direction of Arrival Estimation for Improved Archimedean Spiral Array With MUSIC Algorithm

open access: yesIEEE Access, 2018
Direction-of-Arrival (DOA) estimation capability of sensor arrays is greatly influenced by geometric configuration of arrays. We proposed a new type 2-D planar array, improved Archimedean spiral array (IASA), to arrange sensor elements and enhance the ...
Jin Chen, Sheng Guan, Ying Tong, Lei Yan
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Classification of Gait Type Based on Deep Learning Using Various Sensors with Smart Insole

open access: yesSensors, 2019
In this paper, we proposed a gait type classification method based on deep learning using a smart insole with various sensor arrays. We measured gait data using a pressure sensor array, an acceleration sensor array, and a gyro sensor array built into a ...
Sung-Sin Lee   +2 more
doaj   +1 more source

A super-resolution scanning algorithm for lensless microfluidic imaging using the dual-line array image sensor.

open access: yesPLoS ONE, 2020
The lensless optical fluid microscopy is of great significance to the miniaturization, portability and low cost development of cell detection instruments.
Dian Tian   +4 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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