Results 51 to 60 of about 18,846 (144)

Systematic dissection and trajectory-scanning mutagenesis of the molecular interface that ensures specificity of two-component signaling pathways. [PDF]

open access: yesPLoS Genetics, 2010
Two-component signal transduction systems enable bacteria to sense and respond to a wide range of environmental stimuli. Sensor histidine kinases transmit signals to their cognate response regulators via phosphorylation.
Emily J Capra   +5 more
doaj   +1 more source

ArcB orchestrates the quorum-sensing system to regulate type III secretion system 1 in Vibrio parahaemolyticus

open access: yesGut Microbes, 2023
In many Vibrio species, virulence is regulated by quorum sensing, which is regulated by a complex, multichannel, two-component phosphorelay circuit. Through this circuit, sensor kinases transmit sensory information to the phosphotransferase LuxU via a ...
Ce Zhang   +7 more
doaj   +1 more source

Functional reconstitution of the Salmonella typhimurium PhoQ histidine kinase sensor in proteoliposomes [PDF]

open access: yesBiochemical Journal, 2005
Two-component signal-transduction systems are widespread in bacteria. They are usually composed of a transmembrane histidine kinase sensor and a cytoplasmic response regulator. The PhoP/PhoQ two-component system of Salmonella typhimurium contributes to virulence by co-ordinating the adaptation to low concentrations of environmental Mg2+.
Sarah, Sanowar, Hervé, Le Moual
openaire   +2 more sources

RdsA Is a Global Regulator That Controls Cell Shape and Division in Rhizobium etli

open access: yesFrontiers in Microbiology, 2022
Unlike other bacteria, cell growth in rhizobiales is unipolar and asymmetric. The regulation of cell division, and its coordination with metabolic processes is an active field of research.
Sofía Martínez-Absalón   +3 more
doaj   +1 more source

Stress Sensors and Signal Transducers in Cyanobacteria

open access: yesSensors, 2010
In living cells, the perception of environmental stress and the subsequent transduction of stress signals are primary events in the acclimation to changes in the environment.
Sergey Kryazhov   +5 more
doaj   +1 more source

The extracytoplasmic linker peptide of the sensor protein SaeS tunes the kinase activity required for staphylococcal virulence in response to host signals.

open access: yesPLoS Pathogens, 2015
Bacterial pathogens often employ two-component systems (TCSs), typically consisting of a sensor kinase and a response regulator, to control expression of a set of virulence genes in response to changing host environments.
Qian Liu   +3 more
doaj   +1 more source

Metabolic Responses to Arsenite Exposure Regulated through Histidine Kinases PhoR and AioS in Agrobacterium tumefaciens 5A

open access: yesMicroorganisms, 2020
Arsenite (AsIII) oxidation is a microbially-catalyzed transformation that directly impacts arsenic toxicity, bioaccumulation, and bioavailability in environmental systems.
Rachel A. Rawle   +9 more
doaj   +1 more source

Fatty acid DSF binds and allosterically activates histidine kinase RpfC of phytopathogenic bacterium Xanthomonas campestris pv. campestris to regulate quorum-sensing and virulence. [PDF]

open access: yesPLoS Pathogens, 2017
As well as their importance to nutrition, fatty acids (FA) represent a unique group of quorum sensing chemicals that modulate the behavior of bacterial population in virulence. However, the way in which full-length, membrane-bound receptors biochemically
Zhen Cai   +8 more
doaj   +1 more source

Structural and Enzymatic Insights into the ATP Binding and Autophosphorylation Mechanism of a Sensor Histidine Kinase [PDF]

open access: yesJournal of Biological Chemistry, 2010
DesK is a sensor histidine kinase (HK) that allows Bacillus subtilis to respond to cold shock, triggering the adaptation of membrane fluidity via transcriptional control of a fatty acid desaturase. It belongs to the HK family HPK7, which includes the nitrogen metabolism regulators NarX/Q and the antibiotic sensor LiaS among other important sensor ...
Trajtenberg, Felipe   +4 more
openaire   +3 more sources

The malate sensing two-component system MaeKR is a non-canonical class of sensory complex for C4-dicarboxylates

open access: yesScientific Reports, 2017
Microbial colonization of different environments is enabled to a great extent by the plasticity of their sensory mechanisms, among them, the two-component signal transduction systems (TCS).
L. Miguel-Romero   +5 more
doaj   +1 more source

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