Results 121 to 130 of about 2,274,512 (358)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Sensorial characterization of fibers of some common fruits in Colombia

, 2003
RESUMEN: Actualmente en la investigación y desarrollo de nuevos productos es de gran importancia la evaluación sensorial de las características de las materias primas y del producto obtenido.
Gutiérrez Estrada, Ester Lucía, Medina Montoya, Gilma Beatriz, Román Morales, María Orfilia, Flórez Acosta, Oscar Albeiro, Martínez Álvarez, Olga Lucía   +4 more
core  

Password alimentos #27 – Evaluación sensorial y entrenamiento de jueces expertos para el cacao 

, 2020
Se presenta la evaluación sensorial y entrenamiento de jueces expertos para el cacao, que se necesita para ser un evaluador sensorial, por qué entrenar jueces para evaluar la calidad, proceso de entrenamiento de jueces para evaluar la calidad del cacao ...
Hernández Amaya, Luz Helena
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Dimensionality Reduction of Sensorial Features by Principal Component Analysis for ANN Machine Learning in Tool Condition Monitoring of CFRP Drilling

, 2018
With the aim to perform sensor monitoring of tool conditions in drilling of stacks made of two carbon fiber reinforced plastic (CFRP) laminates, a machine learning procedure based on the acquisition and processing of thrust force, torque, acoustic ...
A. Caggiano, Roberta Angelone, F. Napolitano, L. Nele, R. Teti   +4 more
semanticscholar   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Desenvolvimento de método de qualidade nutricional, sensorial, regulamentar e sustentabilidade no abastecimento de carnes em unidades produtoras de refeições: o exemplo da carne bovina [PDF]

, 2011
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Nutrição, Florianópolis, 2011aquisição de carne em Unidades Produtoras de Refeições é uma etapa determinante para a garantia da ...
Martinelli, Suellen Secchi
core