FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Quality Attributes and Sensory Acceptance of Different Botanical Coffee Co-Products. [PDF]
Foods, 2023 Poláková K +9 more
europepmc +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Effect of inulin in pineapple jam: physicochemical and sensory analysis among school children
O Mundo da Saúde, 2014 The present study aimed to evaluate the sensory acceptability of traditional formulations pineapple jam of inulin additions among school children. We also intended to determine the physicochemical composition of the traditional product and that having a ...
Kétlin Ariane Santos +5 more
doaj
Consumer sensory evaluation of Bulgarian sweet pepper mutant genotypes
Растениевъдни наукиSensory characteristics of fruits of pepper from two mutant genotypes were compared in order to evaluate their quality for market performance. Consumer sensory evaluation was engaged to identify the key sensory properties and to determine overall ...
Dida Dida Iserliyska, Nasya Tomlekova
doaj +1 more source
Combined effect of modified atmosphere packaging and gamma radiation on microbiology and sensory acceptance of refrigerated chicken breast fillets [PDF]
Biotemas, 2010 The aim of this study was to investigate the combined effect of modified atmosphere packaging and irradiation on increase of the shelf-life and sensory acceptance of refrigerated chicken breast fillets.
Samira Pirola Santos Mantilla +5 more
doaj
Pork Consumption Frequencies, Attitudes and Sensory Acceptance of Traditional Products in Lithuania. [PDF]
Foods, 2022 Razmaitė V +3 more
europepmc +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source