Results 31 to 40 of about 4,820 (233)

Somatostatin and Its Receptors in Myocardial Ischemia/Reperfusion Injury and Cardioprotection

open access: yesFrontiers in Pharmacology, 2021
Little is known about the role of the neuropeptide somatostatin (SST) in myocardial ischemia/reperfusion injury and cardioprotection. Here, we investigated the direct cardiocytoprotective effect of SST on ischemia/reperfusion injury in cardiomyocyte ...
Imre Vörös   +31 more
doaj   +1 more source

The chronic protective effects of limb remote preconditioning and the underlying mechanisms involved in inflammatory factors in rat stroke. [PDF]

open access: yesPLoS ONE, 2012
We recently demonstrated that limb remote preconditioning (LRP) protects against focal ischemia measured 2 days post-stroke. Here, we studied whether LRP provides long-term protection and improves neurological function.
Dingtai Wei   +3 more
doaj   +1 more source

Bradykinin mediates cardiac preconditioning at a distance [PDF]

open access: yes, 2000
Preconditioning the heart by brief coronary (CAO) or mesenteric artery occlusion (MAO) can protect against damage during subsequent prolonged CAO and reperfusion. The role of bradykinin (BK) in remote cardiac preconditioning
Regien G. Schoemaker   +5 more
core   +1 more source

Avoiding a feared stimulus: Modelling costly avoidance of learnt fear in a sensory preconditioning paradigm

open access: yes, 2022
Avoidance of learnt fear prevents the onset of a feared stimulus and the threat that follows. In anxiety-related disorders, it turns pathological given its cost and persistence in the absence of realistic threat.
Wong, Alex H. K., Pittig, Andre
core   +1 more source

Role of Myc proto-oncogene as a transcriptional hub to regulate the expression of regeneration-associated genes following preconditioning peripheral nerve injury [PDF]

open access: yes, 2021
Preconditioning peripheral nerve injury enhances the intrinsic growth capacity of DRGs sensory axons by inducing transcriptional upregulation of the regeneration-associated genes (RAGs).
Oh, YJ   +7 more
core   +1 more source

Avoidance but not aversion following sensory preconditioning with flavors: a challenge to stimulus substitution

open access: yes, 2012
After two neutral stimuli have been paired (AB), directly conditioning a response to one of them (A) will also be reflected in a change in responding to the other (B). Standard accounts of this sensory preconditioning effect assume that it is mediated by
Dwyer, Dominic M.   +2 more
core   +1 more source

Temporal structure in associative retrieval

open access: yeseLife, 2015
Electrophysiological data disclose rich dynamics in patterns of neural activity evoked by sensory objects. Retrieving objects from memory reinstates components of this activity. In humans, the temporal structure of this retrieved activity remains largely
Zeb Kurth-Nelson   +4 more
doaj   +1 more source

Sensory preconditioning task.

open access: yes, 2020
(a) Participants learned associations between cue pairs (e.g., A→B) during preconditioning. (b) During conditioning, participants learned associations between the second cue in each pair (B, D) and a monetary outcome ($1, $0).
Geoffrey Schoenbaum (5793443)   +2 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

open access: yesInternational Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam   +2 more
wiley   +1 more source

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