Results 41 to 50 of about 1,534,956 (198)

Sensory nerves in the spotlight of the stem cell niche

Stem Cells Translational Medicine, 2021
Niches are specialized tissue microenvironments that control stem cells functioning. The bone marrow mesenchymal stem cell niche defines a location within the marrow in which mesenchymal stem cells are retained and produce new cells throughout life ...
Caroline C. Picoli, Alinne C. Costa, Beatriz G.S. Rocha, Walison N. Silva, Gabryella S.P. Santos, Pedro H.D.M. Prazeres, Pedro A.C. Costa, Anderson Oropeza, Rodrigo A. daSilva, Vasco A.C. Azevedo, Rodrigo R. Resende, Thiago M. Cunha, Akiva Mintz, Alexander Birbrair   +13 more
doaj   +1 more source

TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation: pro-inflammatory response induced by their activation and their sensitization

Protein & Cell, 2017
Cutaneous neurogenic inflammation (CNI) is inflammation that is induced (or enhanced) in the skin by the release of neuropeptides from sensory nerve endings. Clinical manifestations are mainly sensory and vascular disorders such as pruritus and erythema.
Olivier Gouin, Killian L’Herondelle, Nicolas Lebonvallet, Christelle Le Gall-Ianotto, Mehdi Sakka, Virginie Buhé, Emmanuelle Plée-Gautier, Jean-Luc Carré, Luc Lefeuvre, Laurent Misery, Raphaele Le Garrec   +10 more
doaj   +1 more source

Histomorphological and microanatomical characteristics of the olfactory organ of freshwater carp, Cirrhinus reba (Hamilton)

Archives of Polish Fisheries, 2016
The morphoanatomy, cellular organization, and surface architecture of the olfactory apparatus in Cirrhinus reba (Hamilton) is described using light and scanning electron microscopy.
Ghosh Saroj Kumar, Chakrabarti Padmanabha   +1 more
doaj   +1 more source

Piezo1-pannexin-1-P2X3 axis in odontoblasts and neurons mediates sensory transduction in dentinal sensitivity

Frontiers in Physiology, 2022
According to the “hydrodynamic theory,” dentinal pain or sensitivity is caused by dentinal fluid movement following the application of various stimuli to the dentin surface.
Sadao Ohyama, Sadao Ohyama, Takehito Ouchi, Maki Kimura, Ryuya Kurashima, Keiko Yasumatsu, Daisuke Nishida, Suzuro Hitomi, Suzuro Hitomi, Sobhan Ubaidus, Hidetaka Kuroda, Hidetaka Kuroda, Shinichirou Ito, Masayuki Takano, Kentaro Ono, Toshihide Mizoguchi, Akira Katakura, Yoshiyuki Shibukawa   +17 more
doaj   +1 more source

Neuronal transient receptor potential (TRP) channels and noxious sensory detection in sickle cell disease [PDF]

Neuroscience Letters, 2019
Pain is the leading cause for hospitalization in patients with sickle cell disease (SCD). While the characteristics of SCD pain can vary widely between patients and between phases of the disease (e.g. vasoocclusive crisis pain vs. chronic pain), similar neuronal mechanisms likely underlie the various aspects of nociceptive processing. In the peripheral
Katelyn E, Sadler, Cheryl L, Stucky
openaire   +2 more sources

Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens.

Immunity, 2020
Dendritic cells (DCs) of the cDC2 lineage initiate allergic immunity and in the dermis are marked by their expression of CD301b. CD301b+ dermal DCs respond to allergens encountered in vivo, but not in vitro.
Caroline Perner, C. H. Flayer, Xueping Zhu, Pamela A. Aderhold, Zaynah N. A. Dewan, Tiphaine Voisin, Ryan B. Camire, Ohn Chow, I. Chiu, Caroline L. Sokol   +9 more
semanticscholar   +1 more source

Polarization and migration in the zebrafish posterior lateral line system. [PDF]

PLoS Computational Biology, 2017
Collective cell migration plays an important role in development. Here, we study the posterior lateral line primordium (PLLP) a group of about 100 cells, destined to form sensory structures, that migrates from head to tail in the zebrafish embryo.
Hildur Knutsdottir, Cole Zmurchok, Dhananjay Bhaskar, Eirikur Palsson, Damian Dalle Nogare, Ajay B Chitnis, Leah Edelstein-Keshet   +6 more
doaj   +1 more source

Cell-intrinsic mechanisms of temperature compensation in a grasshopper sensory receptor neuron

eLife, 2014
Changes in temperature affect biochemical reaction rates and, consequently, neural processing. The nervous systems of poikilothermic animals must have evolved mechanisms enabling them to retain their functionality under varying temperatures. Auditory receptor neurons of grasshoppers respond to sound in a surprisingly temperature-compensated manner ...
Roemschied, Frederic A, Eberhard, Monika JB, Schleimer, Jan-Hendrik, Ronacher, Bernhard, Schreiber, Susanne   +4 more
openaire   +5 more sources

TLR7 is expressed by support cells, but not sensory neurons, in ganglia

Journal of Neuroinflammation, 2021
Background Toll-like receptor 7 (TLR7) is an innate immune receptor that detects viral single-stranded RNA and triggers the production of proinflammatory cytokines and type 1 interferons in immune cells. TLR7 agonists also modulate sensory nerve function
Becky J. Proskocil, Karol Wai, Katherine M. Lebold, Mason A. Norgard, Katherine A. Michaelis, Ubaldo De La Torre, Madeline Cook, Daniel L. Marks, Allison D. Fryer, David B. Jacoby, Matthew G. Drake   +10 more
doaj   +1 more source

Muscle-like nicotinic receptor accessory molecules in sensory hair cells of the inner ear [PDF]

Molecular and Cellular Neuroscience, 2008
Nothing is known about the regulation of nicotinic acetylcholine receptors (nAChRs) in hair cells of the inner ear. MuSK, rapsyn and RIC-3 are accessory molecules associated with muscle and brain nAChR function. We demonstrate that these accessory molecules are expressed in the inner ear raising the possibility of a muscle-like mechanism for clustering
Abdullah A, Osman, Angela D, Schrader, Aubrey J, Hawkes, Omar, Akil, Adam, Bergeron, Lawrence R, Lustig, Dwayne D, Simmons   +6 more
openaire   +2 more sources