Results 111 to 120 of about 895,147 (354)

Ventriculo-arterial (VA) coupling and fQRS as new selection criteria for primary prevention ICD placement

Intensive Care Medicine Experimental
For decades, left ventricular ejection fraction (LVEF 
Nathan Engstrom, Hayley L. Letson, Kevin Ng, Geoffrey P. Dobson   +3 more
doaj   +1 more source

Modelling TERT regulation across 19 different cancer types based on the MIPRIP 2.0 gene regulatory network approach

BMC Bioinformatics, 2019
Background Reactivation of the telomerase reverse transcriptase gene TERT is a central feature for unlimited proliferation of the majority of cancers. However, the underlying regulatory processes are only partly understood. Results We assembled regulator
Alexandra M. Poos, Theresa Kordaß, Amol Kolte, Volker Ast, Marcus Oswald, Karsten Rippe, Rainer König   +6 more
doaj   +1 more source

Aetiology of community-acquired neonatal sepsis in low and middle income countries [PDF]

, 2011
99% of the approximate 1 million annual neonatal deaths from life-threatening invasive bacterial infections occur in developing countries, at least 50% of which are from home births or community settings.
Ahmad, Aziez, Campbell, Harry, Jawad, Issrah, Lukšić, Ivana, Nair, Harish, Rudan, Igor, Theodoratou, Evropi, Waters, Donald, Zaidi, Anita K M, Zgaga, Lina   +9 more
core   +1 more source

Recurrent acute thrombocytopenia in the hospitalized patient: Sepsis, DIC, HIT, or antibiotic‐induced thrombocytopenia [PDF]

, 2009
Talla A. Rousan, Ibrahim Aldoss, Benjamin D. Cowley, Brian R. Curtis, Daniel W. Bougie, Richard H. Aster, James N. George   +6 more
openalex   +1 more source

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

Advanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon, Dante Disharoon, Shrijal S. Desai, Baylee Traylor, Emily Gahagan, Emma Quill, Kristin Aldridge, Norman F. Luc, Sonali Rohiwal, Shruti Raghunathan, Rebecca Ahn, Sana Syed, Alexander Dornback, Bipin Chakravarthy Paruchuri, Andrew Ditto, Susan M. Shea, Philip C. Spinella, Matthew D. Neal, Michael A. Bruckman, Christa L. Pawlowski, Anirban Sen Gupta   +20 more
wiley   +1 more source

Smartphone-based pathogen diagnosis in urinary sepsis patients. [PDF]

, 2018
BackgroundThere is an urgent need for rapid, sensitive, and affordable diagnostics for microbial infections at the point-of-care. Although a number of innovative systems have been reported that transform mobile phones into potential diagnostic tools, the
Barnes, Lucien, Choe, Jane, Fitzgibbons, Lynn N, Fox, Gary N, Fried, Jeffrey C, Heithoff, Douglas M, Mahan, Michael J, Mahan, Scott P, Marth, Jamey D, Soh, H Tom, Zambrano, Andrea   +10 more
core  

The endocannabinoid system in sepsis – a potential target to improve microcirculation? [PDF]

, 2011
Christine Lehmann, Mandana Kianian, Juan Zhou, Vladimír Černý, Kelly, Melanie   +4 more
openalex   +1 more source

Biomarkers of sepsis [PDF]

Critical Reviews in Clinical Laboratory Sciences, 2013
Sepsis is an unusual systemic reaction to what is sometimes an otherwise ordinary infection, and it probably represents a pattern of response by the immune system to injury. A hyper-inflammatory response is followed by an immunosuppressive phase during which multiple organ dysfunction is present and the patient is susceptible to nosocomial infection ...
openaire   +2 more sources

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Impact of different anesthetic protocols during anesthesia for the establishment of a porcine model of acute kidney injury

Animal Models and Experimental Medicine
Background During the establishment of a model of acute kidney injury (AKI) in pigs, we observed a high prevalence of malignant hyperthermia (MH). These complications led us to refine the anesthetic protocol.
Axel Guilpin, Mathieu Magnin, Axel Aigle, Timothée Schuhler, Jean‐Yves Ayoub, Romain Lac, Charlotte Slek, Thomas Brichart, Abdessalem Hammed, Vanessa Louzier   +9 more
doaj   +1 more source