Results 101 to 110 of about 1,083,142 (408)
Interpreting Forecasted Vital Signs Using N-BEATS in Sepsis Patients [PDF]
arXiv, 2023 Detecting and predicting septic shock early is crucial for the best possible outcome for patients. Accurately forecasting the vital signs of patients with sepsis provides valuable insights to clinicians for timely interventions, such as administering stabilizing drugs or optimizing infusion strategies.
arxiv
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
Critical Care, 2019 BackgroundSeptic shock is the most severe form of sepsis, in which profound underlying abnormalities in circulatory and cellular/metabolic parameters lead to substantially increased mortality. A clear understanding and up-to-date assessment of the burden
J. Vincent +4 more
semanticscholar +1 more source
Inorganic Nanomaterials Meet the Immune System: An Intricate Balance
Advanced Healthcare Materials, EarlyView.Metal nanomaterials influence the immune responses, such as cytokine production and T‐cell activity. Unintended immune modulation can have significant consequences while its fine‐tuning may transform the oncology care. Within this review, a critical analysis is offered regarding the nano/immune‐interaction and suggests the future research directions to
Gloria Pizzoli +3 more
wiley +1 more source
Polymyxin B Hemoperfusion in Pneumonic Septic Shock Caused by Gram-Negative Bacteria [PDF]
Korean Journal of Critical Care Medicine, 2015 Severe sepsis and septic shock are the main causes of death in critically ill patients. Early detection and appropriate treatment according to guidelines are crucial for achieving favorable outcomes.
Jung-Wan Yoo +6 more
doaj +1 more source
The prevalence of severe sepsis or septic shock in an Irish emergency department [PDF]
, 2018 Severe sepsis and septic shock are among the leading causes of death globally. Despite the central role the emergency department (ED) plays in the early identification of patients presenting to hospital with sepsis, the prevalence of severe sepsis and ...
Fitzpatrick, Fidelma +4 more
core
Altered immune parameters in chronic alcoholic patients at the onset of infection and of septic shock [PDF]
, 2004 INTRODUCTION: Chronic alcoholic patients have a threefold to fourfold increased risk for developing a severe infection or septic shock after surgery, which might be due to altered immune response.
Beller, Stefan +6 more
core +2 more sources
Annals of Intensive Care, 2018 In patients with septic shock, the administration of fluids during initial hemodynamic resuscitation remains a major therapeutic challenge. We are faced with many open questions regarding the type, dose and timing of intravenous fluid administration ...
M. Malbrain +9 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.An injectable polydopamine‐based nanohybrid hydrogel integrates controlled low‐temperature photothermal therapy with potent antibacterial efficacy against MRSA while promoting robust bone regeneration. The hydrogel's composite design triggers HSP70 expression, facilitating osteogenesis and efficient bone formation.
Fang Yang +13 more
wiley +1 more source
Predicting Individual Responses to Vasoactive Medications in Children with Septic Shock [PDF]
arXiv, 2019 Objective: Predict individual septic children's personalized physiologic responses to vasoactive titrations by training a Recurrent Neural Network (RNN) using EMR data. Materials and Methods: This study retrospectively analyzed EMR of patients admitted to a pediatric ICU from 2009 to 2017.
arxiv