Results 21 to 30 of about 1,124,600 (388)

A model of porcine polymicrobial septic shock

open access: yesIntensive Care Medicine Experimental, 2023
Background Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Mortality of patients with sepsis is high and largely unchanged throughout the past decades.
Finnja Marie Zurek-Leffers   +12 more
doaj   +1 more source

Frequency and mortality of sepsis and septic shock in China: a systematic review and meta-analysis

open access: yesBMC Infectious Diseases, 2022
Background Sepsis, a life-threatening organ dysfunction induced by infection, is a major public health problem. This study aimed to evaluate the frequency and mortality of sepsis, severe sepsis, and septic shock in China.
Yan-Cun Liu   +8 more
semanticscholar   +1 more source

Proenkephalin A 119-159 (Penkid) Is an Early Biomarker of Septic Acute Kidney Injury: The Kidney in Sepsis and Septic Shock (Kid-SSS) Study [PDF]

open access: yes, 2018
Introduction: Sepsis is the leading cause of acute kidney injury (AKI) in critically ill patients. The Kidney in Sepsis and Septic Shock (Kid-SSS) study evaluated the value of proenkephalin A 119-159 (penkid)—a sensitive biomarker of glomerular function,
Antonelli, M.   +25 more
core   +2 more sources

Septic shock: perspective methods of diagnostics and therapy based on immunopathogenesis

open access: yesМедицинская иммунология, 2020
Based on the III International Consensus on the definition of Sepsis and Septic Shock (Sepsis-3), the modern definition of septic shock was proposed: “Septic shock is a type of sepsis that is accompanied by severe hemodynamic, metabolic and cellular ...
L. I. Gomanova
doaj   +1 more source

International Consensus Criteria for Pediatric Sepsis and Septic Shock

open access: greenJournal of the American Medical Association (JAMA)
Importance Sepsis is a leading cause of death among children worldwide. Current pediatric-specific criteria for sepsis were published in 2005 based on expert opinion.
Luregn J. Schlapbach   +43 more
openalex   +3 more sources

Management of sepsis and septic shock in the emergency department

open access: yesInternal and Emergency Medicine, 2021
Early management of sepsis and septic shock is crucial for patients’ prognosis. As the Emergency Department (ED) is the place where the first medical contact for septic patients is likely to occur, emergency physicians play an essential role in the early
F. Gavelli, L. Castello, G. Avanzi
semanticscholar   +1 more source

Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children

open access: yesPediatric Critical Care Medicine, 2020
Supplemental Digital Content is available in the text. Objectives: To develop evidence-based recommendations for clinicians caring for children (including infants, school-aged children, and adolescents) with septic shock and other sepsis-associated organ
S. Weiss   +50 more
semanticscholar   +1 more source

Venoarterial extracorporeal membrane oxygenation as mechanical circulatory support in adult septic shock: a systematic review and meta-analysis with individual participant data meta-regression analysis

open access: yesCritical Care, 2021
While recommended by international societal guidelines in the paediatric population, the use of venoarterial extracorporeal membrane oxygenation (VA ECMO) as mechanical circulatory support for refractory septic shock in adults is controversial.
R. Ling   +7 more
semanticscholar   +1 more source

Is there NO treatment for severe sepsis? [PDF]

open access: yes, 2008
Sepsis is a systemic inflammatory response syndrome in the presence of suspected or proven infection, and it may progress to or encompass organ failure (severe sepsis) and hypotension (septic shock).
Bredan, Amin, Cauwels, Anje
core   +2 more sources

Time-to-antibiotics and clinical outcomes in patients with sepsis and septic shock: a prospective nationwide multicenter cohort study

open access: yesCritical Care, 2021
Background Timely administration of antibiotics is one of the most important interventions in reducing mortality in sepsis. However, administering antibiotics within a strict time threshold in all patients suspected with sepsis will require huge amount ...
Y. Im   +38 more
semanticscholar   +1 more source

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