Results 21 to 30 of about 247,348 (342)

Fluid balance and cardiac function in septic shock as predictors of hospital mortality [PDF]

open access: yes, 2013
INTRODUCTION: Septic shock is a major cause of morbidity and mortality throughout the world. Unfortunately, the optimal fluid management of septic shock is unknown and currently is empirical.
Doherty, Joshua A   +5 more
core   +3 more sources

Is there NO treatment for severe sepsis? [PDF]

open access: yes, 2008
Sepsis is a systemic inflammatory response syndrome in the presence of suspected or proven infection, and it may progress to or encompass organ failure (severe sepsis) and hypotension (septic shock).
Bredan, Amin, Cauwels, Anje
core   +2 more sources

Managing septic shock [PDF]

open access: yesF1000 Medicine Reports, 2010
Although several successful clinical trials in the last 2-3 years have been greeted with enthusiasm by intensivists, severe sepsis and septic shock still have increasing incidence and more or less unchanged mortality. Within the last few years, the progress in sepsis research covering definitions, epidemiology, pathophysiology, diagnosis, and standard ...
Gerlach, Herwig, Toussaint, Susanne
openaire   +2 more sources

The Role of Complement System in Septic Shock

open access: yesClinical and Developmental Immunology, 2012
Septic shock is a critical clinical condition with a high mortality rate. A better understanding of the underlying mechanisms is important to develop effective therapies.
Jean Charchaflieh   +8 more
doaj   +1 more source

Characterization of Early Peripheral Immune Responses in Patients with Sepsis and Septic Shock

open access: yesBiomedicines, 2022
(1) Background: Sepsis is a life-threatening condition caused by an abnormal host response to infection that produces altered physiological responses causing tissue damage and can result in organ dysfunction and, in some cases, death.
Jesús Beltrán-García   +11 more
doaj   +1 more source

Characteristics and Outcomes of Patients with Vasoplegic Versus Tissue Dysoxic Septic Shock [PDF]

open access: yes, 2013
Background: The current consensus definition of septic shock requires hypotension after adequate fluid challenge or vasopressor requirement. Some patients with septic shock present with hypotension and hyperlactatemia greater than 2 mmol/L (tissue ...
Jones, Alan E   +6 more
core   +1 more source

Diagnostic value of Pentraxin-3 in patients with sepsis and septic shock in accordance with latest sepsis-3 definitions [PDF]

open access: yes, 2017
Background: Pentraxin-3 (PTX-3) is an acute-phase protein involved in inflammatory and infectious processes. This study assesses its diagnostic and prognostic value in patients with sepsis or septic shock in a medical intensive care unit (ICU). Methods:
A Mantovani   +48 more
core   +1 more source

Septic Shock

open access: yesVeterinary Clinics of North America: Small Animal Practice, 1989
Septic shock is a life-threatening condition that results from the combined effects of bacteria and the host's chemical mediators of inflammation. Of particular detriment is the hyperdynamic and hypodynamic vasomotor instability that severely compromises the patient prior to the onset of overt bacteremia.
Resident, From the Department of Small Animal Clinical Sciences, University of Florida College of Veterinary Medicine, Gainesville, Florida ( host institution )   +2 more
openaire   +5 more sources

Changes in Circulating Procalcitonin Versus C-Reactive Protein in Predicting Evolution of Infectious Disease in Febrile, Critically Ill Patients [PDF]

open access: yes, 2013
Objective:Although absolute values for C-reactive protein (CRP) and procalcitonin (PCT) are well known to predict sepsis in the critically ill, it remains unclear how changes in CRP and PCT compare in predicting evolution of: infectious disease ...
Groeneveld, A.B.J. (Johan)   +1 more
core   +6 more sources

Tricuspid Annular Plane of Systolic Excursion for the Evaluation of Patients with Severe Sepsis and Septic Shock [PDF]

open access: yes, 2020
Introduction: Sepsis is a systemic infection that can rapidly progress into multi organ failure and shock if left untreated. Previous studies have demonstrated the utility of point of care ultrasound (POCUS) in the evaluation of patients with sepsis ...
Ali, Qumber   +7 more
core  

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