Results 61 to 70 of about 1,124,600 (388)
European Journal of Medical ResearchBackground Septic shock, a severe consequence of sepsis, has a high mortality rate. Hypothermia can aggravate the state of septic shock patients, which influences therapeutic response and overall prognosis.
Fen Tan +3 more
doaj +1 more source
Septic shock: treatment and modern interpretation of the issue
Український журнал клінічної хірургіїObjective. To analyse the results of treatment of patients with septic shock, which was carried out in accordance with the decisions of the International Conference on Conciliation and the protocols of the Sepsis–3 guideline. Materials and methods. We
С. D. Shapoval
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Acute kidney injury is associated with a decrease in cortical renal perfusion during septic shock
Critical Care, 2018 Background Renal perfusion status remains poorly studied at the bedside during septic shock. We sought to measure cortical renal perfusion in patients with septic shock during their first 3 days of care using renal contrast enhanced ultrasound (CEUS ...
Anatole Harrois +3 more
doaj +1 more source
The Physiological Basis for Vitamin C as a Potential Treatment for Sepsis [PDF]
, 2019 Accounting for one third of all hospital patient deaths in America, sepsis remains one of the most deadly and complicated conditions that healthcare providers treat.
Johnston, Jennifer
core +1 more source
A fresh look at paralytics in the critically ill: real promise and real concern. [PDF]
, 2012 Neuromuscular blocking agents (NMBAs), or "paralytics," often are deployed in the sickest patients in the intensive care unit (ICU) when usual care fails.
Kenyon, Nicholas J +2 more
core +2 more sources
Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock.
Journal of the American Medical Association (JAMA)Importance The Society of Critical Care Medicine Pediatric Sepsis Definition Task Force sought to develop and validate new clinical criteria for pediatric sepsis and septic shock using measures of organ dysfunction through a data-driven approach ...
L. Sanchez-Pinto +41 more
semanticscholar +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
The Prevalence and Significance of Overt Disseminated Intravascular Coagulation in Patients with Septic Shock in the Emergency Department According to the Third International Consensus Definition [PDF]
Korean Journal of Critical Care Medicine, 2016 Background The prevalence and prognostic value of overt disseminated intravascular coagulation (DIC) in patients with septic shock presenting to emergency departments (EDs) is poorly understood, particularly following the release of a new definition of ...
Byuk Sung Ko +7 more
doaj +1 more source
The Global Burden of Sepsis and Septic Shock
EpidemiologiaA dysregulated host response to infection causes organ dysfunction in sepsis and septic shock, two potentially fatal diseases. They continue to be major worldwide health burdens with high rates of morbidity and mortality despite advancements in medical ...
L. La Via +11 more
semanticscholar +1 more source