Results 61 to 70 of about 1,083,142 (408)

Combination therapy of vitamin C and thiamine for septic shock: a multi-centre, double-blinded randomized, controlled study

open access: yesIntensive Care Medicine, 2020
To evaluate the effects of early combination therapy with intravenous vitamin C and thiamine on recovery from organ failure in patients with septic shock.
S. Hwang   +14 more
semanticscholar   +1 more source

Reconstructing Missing EHRs Using Time-Aware Within- and Cross-Visit Information for Septic Shock Early Prediction [PDF]

open access: yesarXiv, 2022
Real-world Electronic Health Records (EHRs) are often plagued by a high rate of missing data. In our EHRs, for example, the missing rates can be as high as 90% for some features, with an average missing rate of around 70% across all features. We propose a Time-Aware Dual-Cross-Visit missing value imputation method, named TA-DualCV, which spontaneously ...
arxiv  

Transduced PEP-1-Heme Oxygenase-1 Fusion Protein Attenuates Lung Injury in Septic Shock Rats [PDF]

open access: yes, 2018
Oxidative stress and inflammation have been identified to play a vital role in the pathogenesis of lung injury induced by septic shock. Heme oxygenase-1 (HO-1), an effective antioxidant and anti-inflammatory and antiapoptotic substance, has been used for
Jun-Jiao Tang   +4 more
core   +2 more sources

Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial

open access: yesJournal of the American Medical Association (JAMA), 2019
Importance Abnormal peripheral perfusion after septic shock resuscitation has been associated with organ dysfunction and mortality. The potential role of the clinical assessment of peripheral perfusion as a target during resuscitation in early septic ...
G. Hernández   +18 more
semanticscholar   +1 more source

Diastolic shock index and clinical outcomes in patients with septic shock

open access: yesAnnals of Intensive Care, 2020
Background Loss of vascular tone is a key pathophysiological feature of septic shock. Combination of gradual diastolic hypotension and tachycardia could reflect more serious vasodilatory conditions.
G. Ospina-Táscon   +11 more
semanticscholar   +1 more source

The Prevalence and Significance of Overt Disseminated Intravascular Coagulation in Patients with Septic Shock in the Emergency Department According to the Third International Consensus Definition [PDF]

open access: yesKorean Journal of Critical Care Medicine, 2016
Background The prevalence and prognostic value of overt disseminated intravascular coagulation (DIC) in patients with septic shock presenting to emergency departments (EDs) is poorly understood, particularly following the release of a new definition of ...
Byuk Sung Ko   +7 more
doaj   +1 more source

Cutoff Values of Hemodynamic Parameters in Pediatric Refractory Septic Shock

open access: yesChildren, 2022
Background: Refractory septic shock can cause severe morbidities and mortalities in children. Resuscitation based on hemodynamics is important in children with critical illness.
En-Pei Lee   +5 more
doaj   +1 more source

Characteristics and Outcomes of Patients with Vasoplegic Versus Tissue Dysoxic Septic Shock [PDF]

open access: yes, 2013
Background: The current consensus definition of septic shock requires hypotension after adequate fluid challenge or vasopressor requirement. Some patients with septic shock present with hypotension and hyperlactatemia greater than 2 mmol/L (tissue ...
Jones, Alan E   +6 more
core   +1 more source

Diagnostic and Prognostic Significance of the Prothrombin Time/International Normalized Ratio in Sepsis and Septic Shock

open access: yesClinical and Applied Thrombosis/Hemostasis, 2022
Objective The study investigates the diagnostic and prognostic significance of the prothrombin time/international normalized ratio (PT/INR) in patients with sepsis and septic shock.
Tobias Schupp MD   +12 more
doaj   +1 more source

International Consensus Criteria for Pediatric Sepsis and Septic Shock.

open access: yesJournal of the American Medical Association (JAMA)
Importance Sepsis is a leading cause of death among children worldwide. Current pediatric-specific criteria for sepsis were published in 2005 based on expert opinion.
L. Schlapbach   +42 more
semanticscholar   +1 more source

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