Results 61 to 70 of about 1,087,361 (389)

Diagnostic and Prognostic Significance of the Prothrombin Time/International Normalized Ratio in Sepsis and Septic Shock

Clinical and Applied Thrombosis/Hemostasis, 2022
Objective The study investigates the diagnostic and prognostic significance of the prothrombin time/international normalized ratio (PT/INR) in patients with sepsis and septic shock.
Tobias Schupp MD, Kathrin Weidner MD, Jonas Rusnak MD, Schanas Jawhar MS, Jan Forner MS, Floriana Dulatahu MS, Lea Marie Brück MS, Ursula Hoffmann MD, Thomas Bertsch MD, Julian Müller MD, Christel Weiß PhD, Ibrahim Akin MD, Michael Behnes MD   +12 more
doaj   +1 more source

Bioinformatic analysis identifies potential biomarkers and therapeutic targets of septic-shock-associated acute kidney injury

Hereditas, 2021
Background Sepsis and septic shock are life-threatening diseases with high mortality rate in intensive care unit (ICU). Acute kidney injury (AKI) is a common complication of sepsis, and its occurrence is a poor prognostic sign to septic patients.
Yun Tang, Xiaobo Yang, Huaqing Shu, Yuan Yu, Shangwen Pan, Jiqian Xu, You Shang   +6 more
doaj   +1 more source

Usefulness of ischemia-modified albumin in the diagnosis of sepsis/septic shock in the emergency department [PDF]

Clinical and Experimental Emergency Medicine, 2020
Objective No studies have evaluated the diagnostic value of ischemia-modified albumin (IMA) for the early detection of sepsis/septic shock in patients presenting to the emergency department (ED).
Seung Hwa Choo, Yong Su Lim, Jin Seong Cho, Jae Ho Jang, Jea Yeon Choi, Woo Sung Choi, Hyuk Jun Yang   +6 more
doaj   +1 more source

Circulating microparticles from septic shock patients exert differential tissue expression of enzymes related to inflammation and oxidative stress [PDF]

, 2011
Objective: Septic shock is characterized by hypotension and multiple organ failure after infection of microorganisms. Septic shock patients display high levels of circulating microparticles.
F. Meziani, H.Ahmed Mostefai, M.C. Martinez, M.Letizia Mastronardi, P. Asfar, R. Andriantsitohaina   +5 more
core   +3 more sources

Cutoff Values of Hemodynamic Parameters in Pediatric Refractory Septic Shock

Children, 2022
Background: Refractory septic shock can cause severe morbidities and mortalities in children. Resuscitation based on hemodynamics is important in children with critical illness.
En-Pei Lee, Jainn-Jim Lin, Shao-Hsuan Hsia, Oi-Wa Chan, Sheng-Ling Jan, Han-Ping Wu   +5 more
doaj   +1 more source

Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial

Journal of the American Medical Association (JAMA), 2019
Importance Abnormal peripheral perfusion after septic shock resuscitation has been associated with organ dysfunction and mortality. The potential role of the clinical assessment of peripheral perfusion as a target during resuscitation in early septic ...
G. Hernández, G. Ospina-Táscon, L. Damiani, E. Estenssoro, A. Dubin, J. Hurtado, G. Friedman, R. Castro, L. Alegría, J. Teboul, M. Cecconi, Giorgio Ferri, M. Jibaja, Ronald Pairumani, P. Fernández, D. Barahona, Vladimir Granda-Luna, A. Cavalcanti, J. Bakker   +18 more
semanticscholar   +1 more source

Diastolic shock index and clinical outcomes in patients with septic shock

Annals of Intensive Care, 2020
Background Loss of vascular tone is a key pathophysiological feature of septic shock. Combination of gradual diastolic hypotension and tachycardia could reflect more serious vasodilatory conditions.
G. Ospina-Táscon, J. Teboul, G. Hernández, I. Alvarez, Á. I. Sánchez-Ortiz, L. E. Calderón-Tapia, R. Manzano-Nuñez, Edgardo Quiñones, H. Madriñán-Navia, Juan Esteban Ruiz-Yucuma, J. L. Aldana, J. Bakker   +11 more
semanticscholar   +1 more source

Prevalence and Management of Septic Shock among Children Admitted at the Kenyatta National Hospital, Longitudinal Survey

International Journal of Pediatrics, 2019
Background. Paediatric septic shock is a subset of sepsis associated with high mortality. Implementing the existing international Surviving Sepsis Campaign Guidelines 2012 (SSCG) have contributed to reduction of mortality in many places but these have ...
Varsha Vekaria-Hirani, Rashmi Kumar, Rachel N. Musoke, Ezekiel M. Wafula, Idris N. Chipkophe   +4 more
doaj   +1 more source

Acute kidney injury is associated with a decrease in cortical renal perfusion during septic shock

Critical Care, 2018
Background Renal perfusion status remains poorly studied at the bedside during septic shock. We sought to measure cortical renal perfusion in patients with septic shock during their first 3 days of care using renal contrast enhanced ultrasound (CEUS ...
Anatole Harrois, Nicolas Grillot, Samy Figueiredo, Jacques Duranteau   +3 more
doaj   +1 more source

Identification of transcriptomics biomarkers for the early prediction of the prognosis of septic shock from pneumopathies

BMC Infectious Diseases, 2021
Background Identifying the biological subclasses of septic shock might provide specific targeted therapies for the treatment and prognosis of septic shock. It might be possible to find biological markers for the early prediction of septic shock prognosis.
Songchang Shi, Xiaobin Pan, Hangwei Feng, Shujuan Zhang, Songjing Shi, Wei Lin   +5 more
doaj   +1 more source