Results 51 to 60 of about 1,296,938 (317)
Population Ecology, EarlyView.In this study, we compared three methods for kinship identification using different algorithms in samples of wild Pacific bluefin tuna and generated genotyping data. The three methods resulted in different numbers of inferred kinship pairs for both generated and actual data. Particularly for the half‐sibling pairs, considerable number of false‐positive
Yohei Tsukahara +5 more
wiley +1 more source
Fine-tuning structural RNA alignments in the twilight zone
BMC Bioinformatics, 2010 Background A widely used method to find conserved secondary structure in RNA is to first construct a multiple sequence alignment, and then fold the alignment, optimizing a score based on thermodynamics and covariance.
Schirmer Stefanie +2 more
doaj +1 more source
Score distributions of gapped multiple sequence alignments down to the low-probability tail [PDF]
Phys. Rev. E 94, 022127 (2016), 2015 Assessing the significance of alignment scores of optimally aligned DNA or amino acid sequences can be achieved via the knowledge of the score distribution of random sequences. But this requires obtaining the distribution in the biologically relevant high-scoring region, where the probabilities are exponentially small.
arxiv +1 more source
Higher accuracy protein Multiple Sequence Alignment by Stochastic Algorithm [PDF]
, 2010 Multiple Sequence Alignment gives insight into evolutionary, structural and functional relationships among the proteins. Here, a novel Protein Alignment by Stochastic Algorithm (PASA) is developed.
Alpana Dey +4 more
core +1 more source
A Neural Multi-sequence Alignment TeCHnique (NeuMATCH)
, 2018 The alignment of heterogeneous sequential data (video to text) is an important and challenging problem. Standard techniques for this task, including Dynamic Time Warping (DTW) and Conditional Random Fields (CRFs), suffer from inherent drawbacks.
Dogan, Pelin +3 more
core +1 more source
FEBS Letters, EarlyView.Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard +7 more
wiley +1 more source
gpALIGNER: A Fast Algorithm for Global Pairwise Alignment of DNA Sequences [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2011 Bioinformatics, through the sequencing of the full genomes for many species, is increasingly relying on efficient global alignment tools exhibiting both high sensitivity and specificity.
Mostafa Hadian Dehkordi +2 more
doaj
Scaling Laws and Similarity Detection in Sequence Alignment with Gaps [PDF]
, 1998 We study the problem of similarity detection by sequence alignment with gaps, using a recently established theoretical framework based on the morphology of alignment paths.
Drasdo, Dirk +2 more
core +3 more sources
Multiple sequence alignment based on set covers
, 2004 We introduce a new heuristic for the multiple alignment of a set of sequences. The heuristic is based on a set cover of the residue alphabet of the sequences, and also on the determination of a significant set of blocks comprising subsequences of the ...
A. Bahr +15 more
core +2 more sources
Alvira : comparative genomics of viral strains [PDF]
, 2007 The Alvira tool is a general purpose multiple sequence alignment viewer with a special emphasis on the comparative analysis of viral genomes. This new tool has been devised specifically to address the problem of the simultaneous analysis of a large ...
Brodie +10 more
core +2 more sources