Results 51 to 60 of about 4,988,216 (324)

gpALIGNER: A Fast Algorithm for Global Pairwise Alignment of DNA Sequences [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2011
Bioinformatics, through the sequencing of the full genomes for many species, is increasingly relying on efficient global alignment tools exhibiting both high sensitivity and specificity.
Mostafa Hadian Dehkordi   +2 more
doaj  

Higher accuracy protein Multiple Sequence Alignment by Stochastic Algorithm [PDF]

open access: yes, 2010
Multiple Sequence Alignment gives insight into evolutionary, structural and functional relationships among the proteins. Here, a novel Protein Alignment by Stochastic Algorithm (PASA) is developed.
Alpana Dey   +4 more
core   +1 more source

Data-driven network alignment

open access: yes, 2020
Biological network alignment (NA) aims to find a node mapping between species' molecular networks that uncovers similar network regions, thus allowing for transfer of functional knowledge between the aligned nodes.
Gu, Shawn, Milenkovic, Tijana
core   +1 more source

PhAST : pharmacophore alignment search tool [PDF]

open access: yes, 2009
We developed the Pharmacophore Alignment Search Tool (PhAST), a text-based technique for rapid hit and lead structure searching in large compound databases.
Hofmann, Bettina Petra   +4 more
core  

ViralMSA: Massively scalable reference-guided multiple sequence alignment of viral genomes

open access: yesbioRxiv, 2020
Motivation In molecular epidemiology, the identification of clusters of transmissions typically requires the alignment of viral genomic sequence data.
Niema Moshiri
semanticscholar   +1 more source

Incidence and Risk Factors of Serious Osteonecrosis in Pediatric Acute Lymphoblastic Leukemia: A CYP‐C Population‐Based Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteonecrosis (ON) is a debilitating complication of acute lymphoblastic leukemia (ALL) therapy. While numerous studies have explored its incidence and associated risk factors, investigations using large‐scale cohorts remain important to characterize ON across heterogeneous populations.
Noémie de Villiers   +5 more
wiley   +1 more source

LCSkPOA: enabling banded semi-global partial order alignments via efficient and accurate backbone generation through extended LCSk++

open access: yesBMC Bioinformatics
Background Most multiple sequence alignment and string-graph alignment algorithms focus on global alignment, but many applications exist for semi-global and local string-graph alignment.
Minindu Weerakoon   +2 more
doaj   +1 more source

High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABER-TOOTH

open access: yesBMC Bioinformatics, 2010
Background Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become unreliable as they approach the so-called 'twilight zone' where sequence ...
Bastolla Ugo   +3 more
doaj   +1 more source

Reduced space sequence alignment [PDF]

open access: yesBioinformatics, 1997
Sequence alignment is the problem of finding the optimal character-by-character correspondence between two sequences. It can be readily solved in O(n2) time and O(n2) space on a serial machine, or in O(n) time with O(n) space per O(n) processing elements on a parallel machine.
J A, Grice, R, Hughey, D, Speck
openaire   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

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