Results 61 to 70 of about 2,925,732 (310)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

DNA sonification for public engagement in bioinformatics

BMC Research Notes, 2021
Objective Visualisation methods, primarily color-coded representation of sequence data, have been a predominant means of representation of DNA data. Algorithmic conversion of DNA sequence data to sound—sonification—represents an alternative means of ...
Heleen Plaisier, Thomas R. Meagher, Daniel Barker   +2 more
doaj   +1 more source

Comparative DNA sequence analysis of wheat and rice genomes.

Genome Research, 2003
The use of DNA sequence-based comparative genomics for evolutionary studies and for transferring information from model species to crop species has revolutionized molecular genetics and crop improvement strategies.
M. Sorrells, Mauricio La Rota, C. E. Bermudez-Kandianis, R. A. Greene, R. Kantety, J. Munkvold, Miftahudin, A. Mahmoud, Xuefeng Ma, P. Gustafson, L. Qi, Benjamin Echalier, B. Gill, D. Matthews, G. Lazo, S. Chao, O. Anderson, H. Edwards, A. Linkiewicz, J. Dubcovsky, E. Akhunov, J. Dvorak, Deshui Zhang, H. Nguyen, Junhua Peng, N. Lapitan, J. Gonzalez-Hernandez, J. Anderson, Khwaja G. Hossain, V. Kalavacharla, S. Kianian, D. Choi, T. Close, M. Dilbirliği, K. Gill, C. Steber, M. Walker-Simmons, P. McGuire, C. Qualset   +38 more
semanticscholar   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Structure of 5S rDNA sequence of the gibel carp (Carassius gibelio) with 2n=100 chromosomes

Frontiers in Marine Science, 2015
In vertebrate, the 5S ribosomal DNA (rDNA) consists of a conserved coding (transcriptional) unit of 120 bp (5S), which is separated from the next unit by a nontranscribed spacer (NTS). The coding sequence and the NTS together form a repeat unit which can
Lech Kirtiklis
doaj   +1 more source

DNA Sequences as a Medium for Steganography Method of Codon Frequency with Character Frequency [PDF]

Al-Rafidain Journal of Computer Sciences and Mathematics, 2012
The present study included an application of new method of steganography using DNA sequence as a medium for hiding. This method is considered as a secret cover for the secret message (text, image), avoid attention of unauthorized person in addition to be
Sadoon Abdullah, Ahmed Nori
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source