Results 61 to 70 of about 2,798,032 (288)

"Nonrandom" DNA sequence analysis in bacteriophage M13 by the dideoxy chain-termination method.

Proceedings of the National Academy of Sciences of the United States of America, 1982
We describe a rapid "nonrandom" DNA sequence analysis procedure that facilitates the nucleotide sequence determination of large contiguous regions of DNA.
M. Poncz, D. Solowiejczyk, M. Ballantine, E. Schwartz, S. Surrey   +4 more
semanticscholar   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

A conserved sequence extending motif III of the motor domain in the Snf2-family DNA translocase Rad54 is critical for ATPase activity. [PDF]

PLoS ONE, 2013
Rad54 is a dsDNA-dependent ATPase that translocates on duplex DNA. Its ATPase function is essential for homologous recombination, a pathway critical for meiotic chromosome segregation, repair of complex DNA damage, and recovery of stalled or broken ...
Xiao-Ping Zhang, Ryan Janke, James Kingsley, Jerry Luo, Clare Fasching, Kirk T Ehmsen, Wolf-Dietrich Heyer   +6 more
doaj   +1 more source

A DNA sequence analysis package for the IBM personal computer

Nucleic Acids Res., 1984
We present here a collection of DNA sequence analysis programs, called "PC Sequence" (PCS), which are designed to run on the IBM Personal Computer (PC).
L. M. Lagrimini, S. Brentano, J. Donelson   +2 more
semanticscholar   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Microcomputer programs for DNA sequence analysis [PDF]

Nucleic Acids Research, 1982
Computer programs are described which allow (a) analysis of DNA sequences to be performed on a laboratory microcomputer or (b) transfer of DNA sequences between a laboratory microcomputer and another computer system, such as a DNA library. The sequence analysis programs are interactive, do not require prior experience with computers and in many other ...
Bruce Conrad, David W. Mount
openaire   +3 more sources

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Some mathematical problems in genetics

Lietuvos Matematikos Rinkinys, 2007
After an introduction to genetic basics three problems are briefly discussed: microarray data analysis, a definition of noninformative DNA sequence, and genetic sequence alignment. More atention is paid to DNA sequence visualization and regularization of
Marijus Radavičius, Tomas Rekašius, Jurgita Židanavičiūtė   +2 more
doaj   +1 more source

Disease Severity and Molecular Identification of Banana bunchy top virus, Infecting Local Banana in Bali Island

Jurnal Perlindungan Tanaman Indonesia, 2020
Bunchy top symptoms on banana has been reported in Bali Island since early 2011. Symptoms variation were observed in the field similar to infection of Banana bunchy top virus (BBTV).
Gusti Ngurah Alit Susanta Wirya, I Putu Sudiarta, Dewa Gede Wiryangga Selangga   +2 more
doaj   +1 more source

Phylogenetic classification of phytopathogenic mollicutes by sequence analysis of 16S ribosomal DNA.

International Journal of Systematic Bacteriology, 1994
The phylogenetic relationships of 17 phytopathogenic mycoplasmalike organisms (MLOs) representing seven major taxonomic groups established on the basis of MLO 16S ribosomal DNA (rDNA) restriction patterns were examined by performing a sequence analysis ...
E. Seemüller, B. Schneider, R. Mäurer, U. Ahrens, X. Daire, Heike Kison, Karl-Heinz Lorenz, G. Firrao, L. Avinent, B. Sears, E. Stackebrandt   +10 more
semanticscholar   +1 more source