Results 91 to 100 of about 29,786,749 (389)
Twin mitochondrial sequence analysis [PDF]
Molecular Genetics & Genomic Medicine, 2013 AbstractWhen applying genome‐wide sequencing technologies to disease investigation, it is increasingly important to resolve sequence variation in regions of the genome that may have homologous sequences. The human mitochondrial genome challenges interpretation given the potential for heteroplasmy, somatic variation, and homologous nuclear mitochondrial
Yosr Bouhlal +4 more
openaire +3 more sources
Unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis
npj Biofilms and Microbiomes, 2017 Psoriasis: investigating microbial diversity Analysing microbial populations on the skin provides an insight into the diversity of microbes associated with psoriasis.
Adrian Tett +13 more
doaj +1 more source
The SH2 Domain Interaction Landscape
Cell Reports, 2013 Members of the SH2 domain family modulate signal transduction by binding to short peptides containing phosphorylated tyrosines. Each domain displays a distinct preference for the sequence context of the phosphorylated residue.
Michele Tinti +18 more
doaj +1 more source
Mapping the surgery exact sequence for topological manifolds to analysis
, 2016 In this paper we prove the existence of a natural mapping from the surgery exact sequence for topological manifolds to the analytic surgery exact sequence of N. Higson and J. Roe.
Zenobi, Vito Felice
core +1 more source
The establishment of reference sequence for SARS‐CoV‐2 and variation analysis
Journal of Medical Virology, 2020 Starting around December 2019, an epidemic of pneumonia, which was named COVID‐19 by the World Health Organization, broke out in Wuhan, China, and is spreading throughout the world. A new coronavirus, named severe acute respiratory syndrome coronavirus 2
Changtai Wang +6 more
semanticscholar +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Antimicrobial Resistance and Infection Control, 2016 Background A high proportion of Extended-Spectrum-Beta-Lactamase (ESBL) producing Enterobacteriaceae is causing common infections in all regions of the world.
Tolbert Sonda +6 more
doaj +1 more source
Analysis of noise-induced temporal correlations in neuronal spike sequences [PDF]
, 2016 This is a copy of the author 's final draft version of an article published in the journal European physical journal. Special topics. The final publication is available at Springer via http://dx.doi.org/10.1140/epjst/e2016-60024-6We investigate temporal
Masoller Alonso, Cristina +2 more
core +2 more sources
BLAST: at the core of a powerful and diverse set of sequence analysis tools
Nucleic Acids Res., 2004 Basic Local Alignment Search Tool (BLAST) is one of the most heavily used sequence analysis tools available in the public domain. There is now a wide choice of BLAST algorithms that can be used to search many different sequence databases via the BLAST ...
S. D. McGinnis, Thomas L. Madden
semanticscholar +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source