Results 21 to 30 of about 29,786,749 (389)
What Can We Learn from a Metagenomic Analysis of a Georgian Bacteriophage Cocktail?
Phage therapy, a practice widespread in Eastern Europe, has untapped potential in the combat against antibiotic-resistant bacterial infections. However, technology transfer to Western medicine is proving challenging. Bioinformatics analysis could help to
Henrike Zschach+11 more
doaj +1 more source
BEAST: Bayesian evolutionary analysis by sampling trees [PDF]
Background The evolutionary analysis of molecular sequence variation is a statistical enterprise. This is reflected in the increased use of probabilistic models for phylogenetic inference, multiple sequence alignment, and molecular population genetics ...
Drummond, Alexei J., Rambaut, Andrew
core +3 more sources
DnaSP 6: DNA Sequence Polymorphism Analysis of Large Data Sets.
We present version 6 of the DNA Sequence Polymorphism (DnaSP) software, a new version of the popular tool for performing exhaustive population genetic analyses on multiple sequence alignments.
J. Rozas+6 more
semanticscholar +1 more source
Bayesian prediction of microbial oxygen requirement [v1; ref status: indexed, http://f1000r.es/1m6]
Background: Prediction of the optimal habitat conditions for a given bacterium, based on genome sequence alone would be of value for scientific as well as industrial purposes. One example of such a habitat adaptation is the requirement for oxygen.
Dan B. Jensen, David W. Ussery
doaj +1 more source
Alignment-Free Sequence Analysis and Applications. [PDF]
Genome and metagenome comparisons based on large amounts of next generation sequencing (NGS) data pose significant challenges for alignment-based approaches due to the huge data size and the relatively short length of the reads. Alignment-free approaches
Jie Ren+6 more
semanticscholar +1 more source
Quantification of within-sample genetic heterogeneity from SNP-array data
Intra-tumour genetic heterogeneity (ITH) fosters drug resistance and is a critical hurdle to clinical treatment. ITH can be well-measured using multi-region sampling but this is costly and challenging to implement.
Pierre Martinez+5 more
doaj +1 more source
The study of microbial pangenomes relies on the computation of gene families, i.e. the clustering of coding sequences into groups of essentially similar genes. There is no standard approach to obtain such gene families.
Lars-Gustav Snipen, David W Ussery
doaj +1 more source
Sequence of a putative human housekeeping gene (HK33) localized on chromosome 1 [PDF]
A gene (X33) localized on human chromosome 1 has been detected by crossreaction of its fusion protein with a monospecific antiserum directed against human vitamin-D-binding protein (hDBP; group-specific component).
Chirgwin+18 more
core +1 more source
A large number of morphologically normal, fertile, transgenic rice plants were obtained by co-cultivation of rice tissues with Agrobacterium tumefaciens.
Yukoh Hiei+3 more
semanticscholar +1 more source
The study of microbial pangenomes relies on the computation of gene families, i.e. the clustering of coding sequences into groups of essentially similar genes. There is no standard approach to obtain such gene families.
Lars-Gustav Snipen, David W Ussery
doaj +1 more source