Results 21 to 30 of about 2,556,924 (316)
Sequencing Platform Modeling and Analysis [PDF]
Cancer Informatics, 2015 As the cost rapidly declines, the next-generation sequencing (NGS) technologies are becoming the main work horse of modern molecular biology to measure the abundance of genomic markers. NGS offers a number of technical advantages such as a greater dynamic range for measuring abundance and a higher resolution for low abundance molecules; moreover, it ...
Yen-Tsung Huang, Li-Xuan Qin
openaire +4 more sources
Global phylogenetic analysis of contemporary aleutian mink disease viruses (AMDVs)
Virology Journal, 2017 Background Aleutian mink disease has major economic consequences on the mink farming industry worldwide, as it causes a disease that affects both the fur quality and the health and welfare of the mink.
P. Ryt-Hansen +6 more
doaj +1 more source
occumb: An R package for site occupancy modeling of eDNA metabarcoding data
Population Ecology, EarlyView.This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley +1 more source
Outbreak tracking of Aleutian mink disease virus (AMDV) using partial NS1 gene sequencing
Virology Journal, 2017 Background Aleutian Mink Disease (AMD) is an infectious disease of mink (Neovison vison) and globally a major cause of economic losses in mink farming. The disease is caused by Aleutian Mink Disease Virus (AMDV) that belongs to the genus Amdoparvovirus ...
P. Ryt-Hansen +6 more
doaj +1 more source
Analysis of the Sequence Preference of Saporin by Deep Sequencing
ACS Chemical Biology, 2022 Ribosome-inactivating proteins (RIPs) are RNA:adenosine glycosidases that inactivate eukaryotic ribosomes by depurinating the sarcin-ricin loop (SRL) in 28S rRNA. The GAGA sequence at the top of the SRL or at the top of a hairpin loop is assumed to be their target motif.
Samuel Hauf +2 more
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Infection Models for Pine Wilt Disease on the Basis of Vector Behaviors
Population Ecology, EarlyView.Infection models for pine wilt disease without vector density were built to estimate the transmission coefficient of the pathogenic nematode. The models successfully simulated the annual change in the density of infected trees for four pine stands. ABSTRACT Pine wilt disease is caused by the pinewood nematode (Bursaphelenchus xylophilus Steiner et ...
Katsumi Togashi
wiley +1 more source
Classifying Genomic Sequences by Sequence Feature Analysis
Genomics, Proteomics & Bioinformatics, 2005 Abstract Traditional sequence analysis depends on sequence alignment. In this study, we analyzed various functional regions of the human genome based on sequence features, including word frequency, dinucleotide relative abundance, and base-base correlation.
Zhi Hua Liu, Dian Jiao, Xiao Sun
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Sequencing and analysis of bacterial genomes [PDF]
Current Biology, 1996 The complete sequences of two small bacterial genomes have recently become available, and those of several more species should follow within the next two years. Sequence comparisons show that the most bacterial proteins are highly conserved in evolution, allowing predictions to be made about the functions of most products of an uncharacterized genome ...
Kenneth E. Rudd +2 more
openaire +3 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Scientific Reports, 2017 Adverse side effects of cancer agents are of great concern in the context of childhood tumors where they can reduce the quality of life in young patients and cause life-long adverse effects.
Branka Radic-Sarikas +8 more
doaj +1 more source