Results 1 to 10 of about 1,220,765 (311)

Integrating sequence and structural biology with DAS [PDF]

open access: goldBMC Bioinformatics, 2007
Background The Distributed Annotation System (DAS) is a network protocol for exchanging biological data. It is frequently used to share annotations of genomes and protein sequence.
Finn Robert D   +5 more
doaj   +7 more sources

More biology from the sequence. [PDF]

open access: bronzeGenome Biology, 2001
A report on the Cold Spring Harbor meeting on Genome Sequencing and Biology, Cold Spring Harbor, NY, USA, 9-13 May 2001.
Martin S. Taylor
openalex   +4 more sources

Connecting Sequence and Biology in the Laboratory Mouse [PDF]

open access: hybridGenome Research, 2003
The Mouse Genome Sequencing Consortium and the RIKEN Genome Exploration Research grouphave generated large sets of sequence data representing the mouse genome and transcriptome, respectively. These data provide a valuable foundation for genomic research.
Richard M. Baldarelli   +26 more
openalex   +5 more sources

The DNA sequence and biology of human chromosome 19 [PDF]

open access: bronzeNature, 2004
Chromosome 19 has the highest gene density of all human chromosomes, more than double the genome-wide average. The large clustered gene families, corresponding high G + C content, CpG islands and density of repetitive DNA indicate a chromosome rich in biological and evolutionary significance.
Jane Grimwood   +97 more
openalex   +4 more sources

The Multiple Sequence Alignment Problem in Biology [PDF]

open access: greenSIAM Journal on Applied Mathematics, 1988
The study and comparison of sequences of characters from a finite alphabet is relevant to various areas of science, notably molecular biology. The measurement of sequence similarity involves the consideration of the different possible sequence alignments in order to find an optimal one for which the “distance” between sequences is minimum.
Humberto Carrillo-Calvet   +1 more
openalex   +4 more sources

Legume Biology: Sequence to Seeds [PDF]

open access: bronzePlant Physiology, 2007
Research on legumes is driven, to a large extent, by their importance as food crops worldwide. Some 25% of the world's major crop production is derived from legumes, and more than one-third of humanity's nutritional nitrogen requirement comes from legumes.
Mark R. O’Brian, Carroll P. Vance
openalex   +5 more sources

Biology Instructions: A Dataset and Benchmark for Multi-Omics Sequence Understanding Capability of Large Language Models [PDF]

open access: greenarXiv
Large language models have already demonstrated their formidable capabilities in general domains, ushering in a revolutionary transformation. However, exploring and exploiting the extensive knowledge of these models to comprehend multi-omics biology remains underexplored.
Haonan He   +14 more
arxiv   +3 more sources

Human Chromosome 7: DNA Sequence and Biology [PDF]

open access: bronzeScience, 2003
DNA sequence and annotation of the entire human chromosome 7, encompassing nearly 158 million nucleotides of DNA and 1917 gene structures, are presented. To generate a higher order description, additional structural features such as imprinted genes, fragile sites, and segmental duplications were integrated at the level of the DNA sequence with medical ...
Stephen W. Scherer   +89 more
openalex   +9 more sources

The anatomy of an aphid genome: From sequence to biology [PDF]

open access: greenComptes Rendus. Biologies, 2010
In 2009, the genome of the pea aphid (Acyrthosiphon pisum) was sequenced and partially annotated. This means that the scientific community has now access to the genetic material of aphids that are serious pests of plants. The description of an aphid genome is a first step to go deeper in the understanding of the biology of these insects.
Denis Tagu   +5 more
openalex   +7 more sources

CLONEQC: lightweight sequence verification for synthetic biology [PDF]

open access: goldNucleic Acids Research, 2010
Synthetic biology projects aim to produce physical DNA that matches a designed target sequence. Chemically synthesized oligomers are generally used as the starting point for building larger and larger sequences. Due to the error rate of chemical synthesis, these oligomers can have many differences from the target sequence.
Pablo A. Lee   +6 more
openalex   +4 more sources

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