Results 1 to 10 of about 5,730,601 (379)
Integrating sequence and structural biology with DAS [PDF]
BMC Bioinformatics, 2007 Background The Distributed Annotation System (DAS) is a network protocol for exchanging biological data. It is frequently used to share annotations of genomes and protein sequence.
Finn Robert D +5 more
doaj +13 more sources
More biology from the sequence [PDF]
Genome Biology, 2001 A report on the Cold Spring Harbor meeting on Genome Sequencing and Biology, Cold Spring Harbor, NY, USA, 9-13 May ...
Taylor, M S
core +7 more sources
Towards an Encyclopaedia of Sequence Biology [PDF]
Linguistic Frontiers, 2018 In this review, I have presented several topics relevant to the present state and to the future state of the scientific field that I propose to call sequence biology (SB). In some pertinent publications, this field was called DNA linguistics.
A. Bolshoy
semanticscholar +3 more sources
Connecting Sequence and Biology in the Laboratory Mouse [PDF]
Genome Research, 2003 The Mouse Genome Sequencing Consortium and the RIKEN Genome Exploration Research grouphave generated large sets of sequence data representing the mouse genome and transcriptome, respectively. These data provide a valuable foundation for genomic research.
Richard M. Baldarelli +26 more
openalex +5 more sources
Sequence Alignment in Molecular Biology [PDF]
Journal of Computational Biology, 1995 Molecular biology is becoming a computationally intense realm of contemporary science and faces some of the current grand scientific challenges. In its context, tools that identify, store, compare and analyze effectively large and growing numbers of bio-sequences are found of increasingly crucial importance.
Apostolico, Alberto, Fiancarlo, Raffaele
core +7 more sources
The EM Algorithm and the Rise of Computational Biology [PDF]
Statistical Science 2010, Vol. 25, No. 4, 476-491, 2011 In the past decade computational biology has grown from a cottage industry with a handful of researchers to an attractive interdisciplinary field, catching the attention and imagination of many quantitatively-minded scientists. Of interest to us is the key role played by the EM algorithm during this transformation. We survey the use of the EM algorithm
Citable Link +3 more
arxiv +6 more sources
The DNA sequence and biology of human chromosome 19 [PDF]
Nature, 2004 Chromosome 19 has the highest gene density of all human chromosomes, more than double the genome-wide average. The large clustered gene families, corresponding high G + C content, CpG islands and density of repetitive DNA indicate a chromosome rich in biological and evolutionary significance.
Jane Grimwood +97 more
openalex +4 more sources
Legume Biology: Sequence to Seeds [PDF]
Plant Physiology, 2007 Research on legumes is driven, to a large extent, by their importance as food crops worldwide. Some 25% of the world's major crop production is derived from legumes, and more than one-third of humanity's nutritional nitrogen requirement comes from legumes.
Mark R. O’Brian, Carroll P. Vance
openalex +5 more sources
The Multiple Sequence Alignment Problem in Biology [PDF]
SIAM Journal on Applied Mathematics, 1988 The study and comparison of sequences of characters from a finite alphabet is relevant to various areas of science, notably molecular biology. The measurement of sequence similarity involves the consideration of the different possible sequence alignments in order to find an optimal one for which the “distance” between sequences is minimum.
Humberto Carrillo-Calvet +1 more
openalex +4 more sources
Biology Instructions: A Dataset and Benchmark for Multi-Omics Sequence Understanding Capability of Large Language Models [PDF]
arXivLarge language models have already demonstrated their formidable capabilities in general domains, ushering in a revolutionary transformation. However, exploring and exploiting the extensive knowledge of these models to comprehend multi-omics biology remains underexplored.
Haonan He +14 more
arxiv +3 more sources