DnaSP 6: DNA Sequence Polymorphism Analysis of Large Data Sets.
We present version 6 of the DNA Sequence Polymorphism (DnaSP) software, a new version of the popular tool for performing exhaustive population genetic analyses on multiple sequence alignments.
J. Rozas+6 more
semanticscholar +1 more source
Biology of Genomes: making sense of sequence [PDF]
A report on the Biology of Genomes meeting held at Cold Spring Harbor Laboratory, NY, USA, 5-9 May 2009.
openaire +3 more sources
An improved Plasmodium cynomolgi genome assembly reveals an unexpected methyltransferase gene expansion. [PDF]
Background: Plasmodium cynomolgi, a non-human primate malaria parasite species, has been an important model parasite since its discovery in 1907. Similarities in the biology of P.
Berriman, Matt+7 more
core +2 more sources
Sequencing Enabling Design and Learning in Synthetic Biology
The ability to read and quantify nucleic acids such as DNA and RNA using sequencing technologies has revolutionized our understanding of life. With the emergence of synthetic biology, these tools are now being put to work in new ways - enabling de novo biological design.
Gilliot, Pierre-Aurelien M A+1 more
openaire +5 more sources
Complexities of Human Promoter Sequences [PDF]
By means of the diffusion entropy approach, we detect the scale-invariance characteristics embedded in the 4737 human promoter sequences. The exponent for the scale-invariance is in a wide range of $[ {0.3,0.9} ]$, which centered at $\delta_c = 0.66$.
arxiv +1 more source
Estimation of Similarity between DNA Sequences and Its Graphical Representation [PDF]
Bioinformatics, which is now a well known field of study, originated in the context of biological sequence analysis. Recently graphical representation takes place for the research on DNA sequence. Research in biological sequence is mainly based on the function and its structure. Bioinformatics finds wide range of applications specifically in the domain
arxiv +1 more source
MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability
We report a major update of the MAFFT multiple sequence alignment program. This version has several new features, including options for adding unaligned sequences into an existing alignment, adjustment of direction in nucleotide alignment, constrained ...
K. Katoh, D. Standley
semanticscholar +1 more source
Lineage-specific interface proteins match up the cell cycle and differentiation in embryo stem cells
The shortage of molecular information on cell cycle changes along embryonic stem cell (ESC) differentiation prompts an in silico approach, which may provide a novel way to identify candidate genes or mechanisms acting in coordinating the two programs. We
Angela Re+4 more
doaj +1 more source
Pairwise alignment of the DNA sequence using hypercomplex number representation [PDF]
A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the hypercomplex number representation of the DNA base-nucleic acid codes and incorporated with the method of dot matrix analysis and ...
arxiv +1 more source
Quantification of within-sample genetic heterogeneity from SNP-array data
Intra-tumour genetic heterogeneity (ITH) fosters drug resistance and is a critical hurdle to clinical treatment. ITH can be well-measured using multi-region sampling but this is costly and challenging to implement.
Pierre Martinez+5 more
doaj +1 more source