Results 41 to 50 of about 1,180,805 (214)

Development of a Biocontained Toluene-Degrading Bacterium for Environmental Protection

open access: yesMicrobiology Spectrum, 2021
Biocontainment is a safeguard strategy for preventing uncontrolled proliferation of genetically engineered microorganisms (GEMs) in the environment. Biocontained GEMs are designed to survive only in the presence of a specific molecule.
Masahito Ishikawa   +2 more
doaj   +1 more source

Fungal genome sequencing: basic biology to biotechnology [PDF]

open access: yesCritical Reviews in Biotechnology, 2015
The genome sequences provide a first glimpse into the genomic basis of the biological diversity of filamentous fungi and yeast. The genome sequence of the budding yeast, Saccharomyces cerevisiae, with a small genome size, unicellular growth, and rich history of genetic and molecular analyses was a milestone of early genomics in the 1990s.
openaire   +2 more sources

Synthetic biology open language (SBOL) version 3.0.0

open access: yesJournal of Integrative Bioinformatics, 2020
Synthetic biology builds upon genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems.
Baig Hasan   +14 more
doaj   +1 more source

A Hands-On Activity to Demonstrate the Central Dogma of Molecular Biology Via a Simulated VDJ Recombination Activity

open access: yesJournal of Microbiology & Biology Education, 2017
Essential or enduring understandings are often defined as the underlying core concepts or “big ideas” we’d like our students to remember when much of the course content has been forgotten.
Pamela A. Marshall
doaj   +1 more source

Rural Education and the teaching of genetics: an investigative didactic possibility

open access: yesRevista Brasileira de Educação do Campo, 2021
Research related to the genome project, cloning and genetically modified organisms are present inside and outside the school. Such subjects deserve attention in the teaching of genetics due to the difficulties presented by the students, regarding the ...
Kássia Paula Oliveira da Silva   +2 more
doaj   +1 more source

A computational pipeline to visualize DNA-protein binding states using dSMF data

open access: yesSTAR Protocols, 2022
Summary: Here, we present a pipeline to map states of protein-binding DNA in vivo. Our pipeline infers as well as quantifies cooperative binding. Using dual-enzyme single-molecule footprinting (dSMF) data, we show how our workflow identifies binding ...
Satyanarayan Rao, Srinivas Ramachandran
doaj   +1 more source

Predicting translation initiation rates for designing synthetic biology

open access: yesFrontiers in Bioengineering and Biotechnology, 2014
In synthetic biology, precise control over protein expression is required in order to construct functional biological systems. A core principle of the synthetic biology approach is model-guided design and, based on biological understanding of the process,
Benjamin eReeve   +5 more
doaj   +1 more source

Nanopore sequencing unveils the complexity of the cold-activated murine brown adipose tissue transcriptome

open access: yesiScience, 2023
Summary: Alternative transcription increases transcriptome complexity by expression of multiple transcripts per gene. Annotation and quantification of transcripts using short-read sequencing is non-trivial.
Christoph Andreas Engelhard   +4 more
doaj   +1 more source

Impact of the rumen microbiome on milk fatty acid composition of Holstein cattle

open access: yesGenetics Selection Evolution, 2019
Background Fatty acids (FA) in bovine milk derive through body mobilization, de novo synthesis or from the feed via the blood stream. To be able to digest feedstuff, the cow depends on its rumen microbiome. The relative abundance of the microbes has been
Bart Buitenhuis   +6 more
doaj   +1 more source

Bacterial epidemiology and biology - lessons from genome sequencing [PDF]

open access: yesGenome Biology, 2011
Next-generation sequencing has ushered in a new era of microbial genomics, enabling the detailed historical and geographical tracing of bacteria. This is helping to shape our understanding of bacterial evolution.
Parkhill, Julian, Wren, Brendan W
openaire   +3 more sources

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