Results 41 to 50 of about 5,771,427 (358)

Dissecting spatio‐temporal protein networks driving human heart development and related disorders

open access: yesMolecular Systems Biology, 2010
Aberrant organ development is associated with a wide spectrum of disorders, from schizophrenia to congenital heart disease, but systems‐level insight into the underlying processes is very limited. Using heart morphogenesis as general model for dissecting
Kasper Lage   +20 more
doaj   +1 more source

ANALYZING THE GENOMIC VARIATION OF MICROBIAL CELL FACTORIES IN THE ERA OF “NEW BIOTECHNOLOGY”

open access: yesComputational and Structural Biotechnology Journal, 2012
The application of genome-scale technologies, both experimental and in silico, to industrial biotechnology has allowed improving the conversion of biomass-derived feedstocks to chemicals, materials and fuels through microbial fermentation. In particular,
Markus Herrgård, Gianni Panagiotou
doaj   +1 more source

BRL1 and BRL3 are novel brassinosteroid receptors that function in vascular differentiation in Arabidopsis [PDF]

open access: yes, 2004
Plant steroid hormones, brassinosteroids (BRs), are perceived by the plasma membrane-localized leucine-rich-repeat-receptor kinase BRI1. Based on sequence similarity, we have identified three members of the BRI1 family, named BRL1, BRL2 and BRL3.
Caño Delgado, Ana   +8 more
core   +1 more source

Are there laws of genome evolution? [PDF]

open access: yes, 2011
Research in quantitative evolutionary genomics and systems biology led to the discovery of several universal regularities connecting genomic and molecular phenomic variables.
Koonin, Eugene V.
core   +4 more sources

SeaView version 4: A multiplatform graphical user interface for sequence alignment and phylogenetic tree building.

open access: yesMolecular biology and evolution, 2010
We present SeaView version 4, a multiplatform program designed to facilitate multiple alignment and phylogenetic tree building from molecular sequence data through the use of a graphical user interface. SeaView version 4 combines all the functions of the
M. Gouy, Stéphane Guindon, O. Gascuel
semanticscholar   +1 more source

Unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis

open access: yesnpj Biofilms and Microbiomes, 2017
Psoriasis: investigating microbial diversity Analysing microbial populations on the skin provides an insight into the diversity of microbes associated with psoriasis.
Adrian Tett   +13 more
doaj   +1 more source

Decoding Sequence Classification Models for Acquiring New Biological Insights [PDF]

open access: yes, 2010
Classifying biological sequences is one of the most important tasks in computational biology. In the last decade, support vector machines (SVMs) in combination with sequence kernels have emerged as a de-facto standard.
Andreas Kothmeier   +5 more
core   +2 more sources

The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution

open access: yesScience, 2009
A survey of genetic diversity of cattle suggests two domestication events in Asia and selection by husbandry. Not Just Dinner on Legs Several thousand years ago, human beings realized the virtues of domesticating wild animals as easy meat.
C. Elsik, R. Tellam, K. Worley
semanticscholar   +1 more source

Lapatinib potentiates cytotoxicity of  YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter

open access: yesScientific Reports, 2017
Adverse side effects of cancer agents are of great concern in the context of childhood tumors where they can reduce the quality of life in young patients and cause life-long adverse effects.
Branka Radic-Sarikas   +8 more
doaj   +1 more source

The SH2 Domain Interaction Landscape

open access: yesCell Reports, 2013
Members of the SH2 domain family modulate signal transduction by binding to short peptides containing phosphorylated tyrosines. Each domain displays a distinct preference for the sequence context of the phosphorylated residue.
Michele Tinti   +18 more
doaj   +1 more source

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