Results 51 to 60 of about 1,180,805 (214)

A One-Year Introductory Biology Majors’ Lab Sequence Incorporating Vision & Change

open access: yesJournal of Microbiology & Biology Education, 2019
The introduction of Vision and Change by AAAS and the recommendation that biology departments amend their curricula to focus on key concepts and skills necessary for graduates have led to a re-envisioning of introductory curricula across the nation. Many
Merrilee F. Guenther   +2 more
doaj   +1 more source

Applications of next‐generation sequencing in plant biology [PDF]

open access: yesAmerican Journal of Botany, 2012
The last several years have seen revolutionary advances in DNA sequencing technologies with the advent of next‐generation sequencing (NGS) techniques. NGS methods now allow millions of bases to be sequenced in one round, at a fraction of the cost relative to traditional Sanger sequencing.
Ashley N, Egan   +2 more
openaire   +2 more sources

Protocol for analysis of single-cell sequencing data by Seqtometry

open access: yesSTAR Protocols
Summary: Seqtometry (sequencing-to-measurement) is an analytical platform for single-cell analysis based on direct profiling of gene expression and accessibility achieved by advanced scoring with gene signatures.
Robert Kousnetsov, Daniel Hawiger
doaj   +1 more source

Protocol for constructing glycan biosynthetic networks using glycowork

open access: yesSTAR Protocols
Summary: Glycans, present across all domains of life, comprise a wide range of monosaccharides assembled into complex, branching structures. Here, we present an in silico protocol to construct biosynthetic networks from a list of observed glycans using ...
Jon Lundstrøm   +2 more
doaj   +1 more source

Protocol for genetic load analysis in caribou using a modified genomic evolutionary rate profiling

open access: yesSTAR Protocols
Summary: Here, we present a protocol to analyze genetic load in caribou (Rangifer tarandus) using a modified version of the genomic evolutionary rate profiling (GERP) program.
Rebecca S. Taylor   +3 more
doaj   +1 more source

AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research

open access: yesPLoS Biology, 2023
In this issue of PLOS Biology, Ibrahim and colleagues demonstrate how AlphaFold-multimer, an artificial intelligence–based structure prediction tool, can be used to identify sequence motifs binding to the ATG8 family of proteins central to autophagy ...
Hallvard Lauritz Olsvik, Terje Johansen
doaj  

Guide for phenotype-specific profiling of DNA G-quadruplex-regulated genes

open access: yesSTAR Protocols
Summary: DNA G-quadruplex (G4) is a non-canonical four-stranded secondary structure that has been shown to play a role in epigenetic modulation of gene expression.
Zhuoyang Zhao   +3 more
doaj   +1 more source

Natural genetic variation impacts expression levels of coding, non‐coding, and antisense transcripts in fission yeast

open access: yesMolecular Systems Biology, 2014
Our current understanding of how natural genetic variation affects gene expression beyond well‐annotated coding genes is still limited. The use of deep sequencing technologies for the study of expression quantitative trait loci (eQTLs) has the potential ...
Mathieu Clément‐Ziza   +12 more
doaj   +1 more source

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