Results 51 to 60 of about 5,730,601 (379)
The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution
Science, 2009 A survey of genetic diversity of cattle suggests two domestication events in Asia and selection by husbandry. Not Just Dinner on Legs Several thousand years ago, human beings realized the virtues of domesticating wild animals as easy meat.
C. Elsik, R. Tellam, K. Worley
semanticscholar +1 more source
Genomics and proteomics: a signal processor's tour [PDF]
, 2004 The theory and methods of signal processing are becoming increasingly important in molecular biology. Digital filtering techniques, transform domain methods, and Markov models have played important roles in gene identification, biological sequence ...
Vaidyanathan, P. P.
core +2 more sources
Detecting sequence signals in targeting peptides using deep learning
Life Science Alliance, 2019 During the development of TargetP 2.0, a state-of-the-art method to predict targeting signal, we find a previously overlooked biological signal for subcellular targeting using the output from a deep learning method.
J. J. Almagro Armenteros +6 more
semanticscholar +1 more source
Cancer biology deciphered by single-cell transcriptomic sequencing [PDF]
Protein & Cell, 2021 AbstractTumors are complex ecosystems in which heterogeneous cancer cells interact with their microenvironment composed of diverse immune, endothelial, and stromal cells. Cancer biology had been studied using bulk genomic and gene expression profiling, which however mask the cellular diversity and average the variability among individual molecular ...
Yanmeng Li, Jianshi Jin, Fan Bai
openaire +2 more sources
Unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis
npj Biofilms and Microbiomes, 2017 Psoriasis: investigating microbial diversity Analysing microbial populations on the skin provides an insight into the diversity of microbes associated with psoriasis.
Adrian Tett +13 more
doaj +1 more source
The SH2 Domain Interaction Landscape
Cell Reports, 2013 Members of the SH2 domain family modulate signal transduction by binding to short peptides containing phosphorylated tyrosines. Each domain displays a distinct preference for the sequence context of the phosphorylated residue.
Michele Tinti +18 more
doaj +1 more source
Developing and applying heterogeneous phylogenetic models with XRate [PDF]
, 2012 Modeling sequence evolution on phylogenetic trees is a useful technique in computational biology. Especially powerful are models which take account of the heterogeneous nature of sequence evolution according to the "grammar" of the encoded gene features.
A Heger +32 more
core +4 more sources
Multiple sequence alignment with the Clustal series of programs
Nucleic Acids Res., 2003 The Clustal series of programs are widely used in molecular biology for the multiple alignment of both nucleic acid and protein sequences and for preparing phylogenetic trees.
Chenna Ramu +6 more
semanticscholar +1 more source
Scientific Reports, 2017 Adverse side effects of cancer agents are of great concern in the context of childhood tumors where they can reduce the quality of life in young patients and cause life-long adverse effects.
Branka Radic-Sarikas +8 more
doaj +1 more source
Cancer systems biology in the genome sequencing era: Part 1, dissecting and modeling of tumor clones and their networks [PDF]
, 2014 Recent tumor genome sequencing confirmed that one tumor often consists of multiple cell subpopulations (clones) which bear different, but related, genetic profiles such as mutation and copy number variation profiles. Thus far, one tumor has been viewed as a whole entity in cancer functional studies.
arxiv +1 more source