Results 61 to 70 of about 5,758,485 (356)

The genome sequence of Drosophila melanogaster.

Science, 2000
The fly Drosophila melanogaster is one of the most intensively studied organisms in biology and serves as a model system for the investigation of many developmental and cellular processes common to higher eukaryotes, including humans.
M. Adams, S. Celniker, R. Holt, C. Evans, J. Gocayne, P. Amanatides, S. Scherer, P. Li, R. Hoskins, R. Galle, R. George, S. Lewis, S. Richards, M. Ashburner, S. Henderson, G. Sutton, J. Wortman, M. Yandell, Q. Zhang, L. Chen, R. Brandon, Y. Rogers, R. Blazej, M. Champe, B. Pfeiffer, K. Wan, C. Doyle, E. G. Baxter, G. Helt, C. Nelson, G. Gábor, J. F. Abril, A. Agbayani, H. An, C. Andrews-Pfannkoch, D. Baldwin, R. Ballew, A. Basu, J. Baxendale, L. Bayraktaroglu, E. Beasley, K. Beeson, P. Benos, B. Berman, D. Bhandari, S. Bolshakov, D. Borkova, M. Botchan, J. Bouck, P. Brokstein, P. Brottier, K. C. Burtis, D. Busam, H. Butler, É. Cadieu, A. Center, I. Chandra, J. Cherry, S. Cawley, C. Dahlke, L. Davenport, P. Davies, B. de Pablos, A. Delcher, Z. Deng, A. D. Mays, I. Dew, S. Dietz, K. Dodson, L. Doup, M. Downes, S. Dugan-Rocha, B. Dunkov, P. Dunn, K. Durbin, C. Evangelista, C. Ferraz, S. Ferriera, W. Fleischmann, C. Fosler, A. Gabrielian, N. Garg, W. Gelbart, K. Glasser, A. Glodek, F. Gong, J. H. Gorrell, Z. Gu, P. Guan, M. Harris, N. Harris, D. Harvey, T. J. Heiman, J. Hernandez, J. Houck, D. Hostin, K. Houston, T. Howland, M. Wei, C. Ibegwam, M. Jalali, F. Kalush, G. Karpen, Z. Ke, J. Kennison, K. Ketchum, B. E. Kimmel, C. Kodira, C. Kraft, S. Kravitz, D. Kulp, Z. Lai, P. Lasko, Y. Lei, A. Levitsky, J. Li, Z. Li, Y. Liang, X. Lin, X. Liu, B. Mattei, T. McIntosh, M. P. McLeod, D. McPherson, G. Merkulov, N. Milshina, C. Mobarry, J. Morris, A. Moshrefi, Stephen M. Mount, M. Moy, B. Murphy, L. Murphy, D. Muzny, D. Nelson, D. Nelson, K. Nelson, K. Nixon, D. Nusskern, J. Pacleb, M. Palazzolo, G. Pittman, S. Pan, J. Pollard, V. Puri, M. G. Reese, K. Reinert, K. Remington, R. Saunders, F. Scheeler, H. Shen, B. Shue, I. Sidén-Kiamos, M. Simpson, M. Skupski, T. Smith, E. Spier, A. Spradling, M. Stapleton, R. Strong, E. Sun, Rob Svirskas, C. Tector, R. Turner, E. Venter, A. H. Wang, X. Wang, Z. Y. Wang, D. Wassarman, G. Weinstock, J. Weissenbach, S. Williams, WoodageT, K. Worley, D. Wu, S. Yang, Q. Yao, J. Ye, R. Yeh, J. Zaveri, M. Zhan, G. Zhang, Q. Zhao, L. Zheng, X. H. Zheng, F. Zhong, W. Zhong, X. Zhou, S. Zhu, X. Zhu, H. Smith, R. Gibbs, E. Myers, G. Rubin, J. Venter   +194 more
semanticscholar   +1 more source

The unpredictably eruptive dynamics of spruce budworm populations in eastern Canada

Population Ecology, EarlyView.
We examine historical population data for spruce budworm from several locations through the period 1930–1997, and use density‐dependent recruitment curves to test whether the pattern of population growth over time is more consistent with Royama's (1984; Ecological Monographs 54:429–462) linear R(t) model of harmonic oscillation at Green River New ...
Barry J. Cooke, Jacques Régnière
wiley   +1 more source

Building Block and Building Rule: Dual Descriptor Method for Biological Sequence Analysis [PDF]

, 2008
The emergence of “Systems Biology” in recent years highlights the systematic viewpoint of bio-system modeling. Building on such a background, Dual Descriptor Method, a generic methodology for biological sequence analysis is proposed. From a
Bin-Guang Ma
core   +1 more source

Fungal genome sequencing: basic biology to biotechnology [PDF]

Critical Reviews in Biotechnology, 2015
The genome sequences provide a first glimpse into the genomic basis of the biological diversity of filamentous fungi and yeast. The genome sequence of the budding yeast, Saccharomyces cerevisiae, with a small genome size, unicellular growth, and rich history of genetic and molecular analyses was a milestone of early genomics in the 1990s.
openaire   +3 more sources

Sequencing the Biology of Entry: The Retroviral env Gene [PDF]

, 2017
The surface envelope protein of any virus is major determinant of the host cell that is infected and as a result a major determinant of viral pathogenesis. Retroviruses have a single surface protein named Env. It is a trimer of heterodimers and is responsible for binding to the host cell receptor and mediating fusion between the viral and host ...
Shuntai Zhou, Ronald Swanstrom, William D. Graham   +2 more
openaire   +3 more sources

Deep learning sequence-based ab initio prediction of variant effects on expression and disease risk

Nature Genetics, 2018
Key challenges for human genetics, precision medicine and evolutionary biology include deciphering the regulatory code of gene expression and understanding the transcriptional effects of genome variation.
Jian Zhou, Chandra L. Theesfeld, K. Yao, Kathleen M. Chen, A. Wong, O. Troyanskaya   +5 more
semanticscholar   +1 more source

occumb: An R package for site occupancy modeling of eDNA metabarcoding data

Population Ecology, EarlyView.
This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley   +1 more source

Development of a Biocontained Toluene-Degrading Bacterium for Environmental Protection

Microbiology Spectrum, 2021
Biocontainment is a safeguard strategy for preventing uncontrolled proliferation of genetically engineered microorganisms (GEMs) in the environment. Biocontained GEMs are designed to survive only in the presence of a specific molecule.
Masahito Ishikawa, Takaaki Kojima, Katsutoshi Hori   +2 more
doaj   +1 more source

G-quadruplexes and their regulatory roles in biology

Nucleic Acids Research, 2015
‘If G-quadruplexes form so readily in vitro, Nature will have found a way of using them in vivo’ (Statement by Aaron Klug over 30 years ago). During the last decade, four-stranded helical structures called G-quadruplex (or G4) have emerged from being a ...
D. Rhodes, H. Lipps
semanticscholar   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

FEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source