Results 61 to 70 of about 5,890,604 (383)

Reagent and laboratory contamination can critically impact sequence-based microbiome analyses

BMC Biology, 2014
BackgroundThe study of microbial communities has been revolutionised in recent years by the widespread adoption of culture independent analytical techniques such as 16S rRNA gene sequencing and metagenomics.
S. Salter, M. Cox, E. Turek, S. Calus, W. Cookson, M. Moffatt, P. Turner, J. Parkhill, N. Loman, A. Walker   +9 more
semanticscholar   +1 more source

Bioinformatics Databases: State of the Art and Research Perspectives [PDF]

, 2003
Bioinformatics or computational biology, i.e. the application of mathematical and computer science methods to solving problems in molecular biology that require large scale data, computation, and analysis, is a research area currently receiving a ...
Bry, François, Kröger, Peer
core   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

More Mouldy Data: Another mycoplasma gene jumps the silicon barrier into the human genome

, 2011
The human genome sequence database contains DNA sequences very like those of mycoplasma molds. It appears such moulds infect not only molecular Biology laboratories but were picked up by experimenters from contaminated samples and inserted into GenBank ...
Arno, M. J., Langdon, W. B.
core   +1 more source

SpBase: the sea urchin genome database and web site [PDF]

, 2008
SpBase is a system of databases focused on the genomic information from sea urchins and related echinoderms. It is exposed to the public through a web site served with open source software (http://spbase.org/). The enterprise was undertaken to provide an
A. Yuan, Altschul, Cai, Curwen, D. He, Davidson, Davidson, E. Davidson, Gonzalez, Havlak, Howard-Ashby, Howe, Littlewood, M. Samanta, M  ller, Oliveri, Poustka, R. A. Cameron, Salamov, Samanta, Sea Urchin Genome Sequencing Consortium, Sodergren, Springer, Stein, Wei   +24 more
core   +4 more sources

Sequencing the Biology of Entry: The Retroviral env Gene [PDF]

, 2017
The surface envelope protein of any virus is major determinant of the host cell that is infected and as a result a major determinant of viral pathogenesis. Retroviruses have a single surface protein named Env. It is a trimer of heterodimers and is responsible for binding to the host cell receptor and mediating fusion between the viral and host ...
Swanstrom, Ronald, Graham, William D., Zhou, Shuntai   +2 more
openaire   +2 more sources

Human Chromosome 7: DNA Sequence and Biology [PDF]

Science, 2003
DNA sequence and annotation of the entire human chromosome 7, encompassing nearly 158 million nucleotides of DNA and 1917 gene structures, are presented. To generate a higher order description, additional structural features such as imprinted genes, fragile sites, and segmental duplications were integrated at the level of the DNA sequence with medical ...
Scherer, Sw, Cheung, J, Macdonald, Jr, Osborne, Lr, Nakabayashi, K, Herbrick, J., Carson, Ar, Parker Katiraee, L, Skaug, J, Khaja, R, Zhang, J, Hudek, Ak, Li, M, Haddad, M, Duggan, Ge, Fernandez, Ba, Kanematsu, E, Gentles, S, Christopoulos, Cc, Choufani, S, Kwasnicka, D, Zheng, Xh, Lai, Z, Nusskern, D, Zhang, Q, Gu, Z, Lu, F, Zeesman, S, Nowaczyk, Mj, Teshima, I, Chitayat, D, Shuman, C, Weksberg, R, Zackai, Eh, Grebe, Ta, Cox, Sr, Kirkpatrick, Sj, Rahman, N, Friedman, Jm, Heng, Hhq, Pelicci, Pg, LO COCO, FRANCESCO, Belloni, E, Shaffer, Lg, Pober, B, Morton, Cc, Gusella, Jf, Bruns, Gap, Korf, Br, Quade, Bj, Ligon, Ah, Ferguson, H, Higgins, Aw, Leach, Nt, Herrick, Sr, Lemyre, E, Farra, Cg, Kim, H., Summers, Am, Gripp, Kw, Roberts, W, Szatmari, P, Winsor, Ejt, Grzeschik, K., Teebi, A, Minassian, Ba, Kere, J, Armengol, L, Pujana, Ma, Estivill, X, Wilson, Md, Koop, Bf, Tosi, S, Moore, Ge, Boright, Ap, Zlotorynski, E, Kerem, B, Kroisel, Pm, Petek, E, Oscier, Dg, Mould, Sj, Dohner, H, Dohner, K, Rommens, Jm, Vincent, Jb, Venter, Jc, Li, Pw, Mural, Rj, Adams, Md, Tsui, L.   +89 more
openaire   +6 more sources

Development of a Biocontained Toluene-Degrading Bacterium for Environmental Protection

Microbiology Spectrum, 2021
Biocontainment is a safeguard strategy for preventing uncontrolled proliferation of genetically engineered microorganisms (GEMs) in the environment. Biocontained GEMs are designed to survive only in the presence of a specific molecule.
Masahito Ishikawa, Takaaki Kojima, Katsutoshi Hori   +2 more
doaj   +1 more source

Representation learning applications in biological sequence analysis

bioRxiv, 2021
Remarkable advances in high-throughput sequencing have resulted in rapid data accumulation, and analyzing biological (DNA/RNA/protein) sequences to discover new insights in biology has become more critical and challenging.
Hitoshi Iuchi, Taro Matsutani, Keisuke Yamada, Natsuki Iwano, Shunsuke Sumi, S. Hosoda, Shitao Zhao, Tsukasa Fukunaga, Michiaki Hamada   +8 more
semanticscholar   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source