Abundance of intrinsic disorder in SV-IV, a multifunctional androgen-dependent protein secreted from rat seminal vesicle [PDF]
The potent immunomodulatory, anti-inflammatory and procoagulant properties of the protein no. 4 secreted from the rat seminal vesicle epithelium (SV-IV) have been previously found to be modulated by a supramolecular monomer-trimer ...
Ambrosone +66 more
core +3 more sources
Predicting the functional consequences of non-synonymous single nucleotide polymorphisms in IL8 gene
Here we report an in-silico approach for identification, characterization and validation of deleterious non-synonymous SNPs (nsSNPs) in the interleukin-8 gene using three steps.
Tikam Chand Dakal +5 more
doaj +1 more source
The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase. [PDF]
Autoantibodies to mitochondrial antigens are characteristic of the autoimmune liver disease primary biliary cirrhosis (PBC), but the precise antigenic determinants recognized by these antibodies have not been defined.
Ansari, A +4 more
core
Homology and conservation of amino acids in E-protein sequences of dengue serotypes
Abstract Objective To identify the homology and phylogenetic relationship among the four dengue virus (DENV) serotypes, and conservation of amino acid in E-proteins and to find out the phylogenetic relationship among the strains of four DENV serotypes.
Ramesh Venkatachalam +1 more
openaire +1 more source
The chitinase C gene PsChiC from Pseudomonas sp. and its synergistic effects on larvicidal activity
Pseudomonas sp. strain TXG6-1, a chitinolytic gram-negative bacterium, was isolated from a vegetable field in Taixing city, Jiangsu Province, China. In this study, a Pseudomonas chitinase C gene (PsChiC) was isolated from the chromosomal DNA of this ...
Wanfang Zhong, Shaojun Ding, Huifang Guo
doaj +1 more source
Loop B is a major structural component of the 5-HT3 receptor [PDF]
The 5-HT3 receptor belongs to a family of therapeutically important neurotransmitter-gated receptors whose ligand binding sites are formed by the convergence of six peptide loops (A-F).
Thompson, Andrew J. +2 more
core +2 more sources
The JC polyoma viral coat protein VP1 was analyzed for amino acid sequences homologies to the IDSP sequence which mediates binding of VLA-4 (integrin alpha 4) to vascular cell adhesion molecule 1.
Michael Andrew Meyer
doaj +1 more source
CARE1, a TY3-gypsy long terminal repeat retrotransposon in the food legume chickpea (Cicer arietinum L) [PDF]
We report a novel Ty3-gypsy long terminal repeat retrotransposon CARE1 (_Cicer arietinum_ retro-element 1) in chickpea. This 5920-bp AT-rich (63%) element carries 723-bp 5' and 897-bp 3' LTRs respectively flanking an internal region of 4300-bp.
Kailash C. Upadhyaya, Manoj D. R. Rajput
core +1 more source
Membrane-bound desaturases are physiologically and industrially important enzymes that are involved in the production of diverse fatty acids such as polyunsaturated fatty acids and their derivatives. Here, we identified amino acid residues that determine
Kenshi Watanabe +5 more
doaj +1 more source
The Site-Specific Amino Acid Preferences of Homologous Proteins Depend on Sequence Divergence
The propensity of protein sites to be occupied by any of the 20 amino acids is known as site-specific amino acid preferences (SSAP). Under the assumption that SSAP are conserved among homologs, they can be used to parameterize evolutionary models for the reconstruction of accurate phylogenetic trees.
openaire +2 more sources

