Results 101 to 110 of about 910,209 (262)

Sequencing Games with Repeated Players [PDF]

Two classes of one machine sequencing situations are considered in which each job corresponds to exactly one player but a player may have more than one job to be processed, so called RP(repeated player) sequencing situations.In max-RP sequencing ...
Borm, P.E.M., Estevez Fernandez, M.A., Hamers, H.J.M., Calleja, P.   +3 more
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

SCORM Sequencing Testing for Sequencing Control Mode [PDF]

, 2010
In SCORM 2004 defines the sequencing information that describes how SCORM-conformant content may be sequenced to the learner through a set of learner or system-initiated navigation events.
Chang, Hsuan-Pu; Wang, Chun-Chia; Wang, Te-Hua; Jan, Kuen Han; Shih,Timothy K., Hsuan-Pu Chang; Chun-Chia Wang; Kuen Han Jan;Timothy K. Shih   +1 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Convex Games with Countable Number of Players and Sequencing Situations [PDF]

AMS classification: 91A12;Cooperative games;countable number of players;convexity;infinite sequencing ...
Tijs, S.H., Llorca, N., Fragnelli, V., Sánchez-Soriano, J.   +3 more
core  

Genome sequencing defines phylogeny and spread of methicillin-resistant Staphylococcus aureus in a high transmission setting. [PDF]

, 2014
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of nosocomial infection. Whole-genome sequencing of MRSA has been used to define phylogeny and transmission in well-resourced healthcare settings, yet the greatest burden of nosocomial ...
Thaipadungpanit, J, Holden, MTG, Cauchemez, S, Jombart, Thibaut, Tong, SY, Nickerson, Emma K, Hongsuwan, M, Cori, A, Cauchemez, Simon, Holden, Matthew T G, Parkhill, J, Köser, CU, Tong, SYC, Nickerson, EK, Day, Nicholas P, Day, NP, Holden, MT, Fraser, C, Tong, Steven Y C, Fraser, Christophe, Limmathurotsakul, Direk, Limmathurotsakul, D, Cooper, Ben, Wuthiekanun, Vanaporn, Peacock, SJ, Köser, Claudio U, Wuthiekanun, V, Cooper, BS, Cori, Anne, Parkhill, Julian, Cooper, Ben S, Day, Nicholas, Thaipadungpanit, Janjira, Peacock, Sharon J, Jombart, T, Hongsuwan, Maliwan   +35 more
core   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Comparative genomics of the miniature wasp and pest control agent Trichogramma pretiosum

BMC Biology, 2018
Background Trichogrammatids are minute parasitoid wasps that develop within other insect eggs. They are less than half a millimeter long, smaller than some protozoans.
Amelia R. I. Lindsey, Yogeshwar D. Kelkar, Xin Wu, Dan Sun, Ellen O. Martinson, Zhichao Yan, Paul F. Rugman-Jones, Daniel S. T. Hughes, Shwetha C. Murali, Jiaxin Qu, Shannon Dugan, Sandra L. Lee, Hsu Chao, Huyen Dinh, Yi Han, Harsha Vardhan Doddapaneni, Kim C. Worley, Donna M. Muzny, Gongyin Ye, Richard A. Gibbs, Stephen Richards, Soojin V. Yi, Richard Stouthamer, John H. Werren   +23 more
doaj   +1 more source

Sequencing Interval Situations and Related Games [PDF]

In this paper we consider one-machine sequencing situations with interval data. We present different possible scenarioes and extend classical results on well known rules and on sequencing games to the interval setting.cooperative games;interval data ...
Brânzei, R., Tijs, S.H., Alparslan-Gok, S.Z., Fragnelli, V.   +3 more
core