Results 111 to 120 of about 2,098,916 (269)
Comparative performance of the BGI and Illumina sequencing technology for single-cell RNA-sequencing
, 2020 The libraries generated by high-throughput single cell RNA-sequencing (scRNA-seq) platforms such as the Chromium from 10x Genomics require considerable amounts of sequencing, typically due to the large number of cells.
Senabouth, A (15675581) +14 more
core
Sequencing of learning activities oriented towards reuse and auto-organization for intelligent tutoring systems [PDF]
, 2007 Three have been the main contributions of this thesis. First, a platform for the deployment of Intelligent Tutoring Systems (ITS) with a modular architecture has been designed.
Gutiérrez Santos, Sergio
core
We introduce the notion of a Morse sequence, which provides a simple and effective approach to discrete Morse theory. A Morse sequence is a sequence composed solely of two elementary operations, that is, expansions (the inverse of a collapse), and fillings (the inverse of a perforation).
openaire +3 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Sequencing mixed-model assembly lines in just-in-time production systems
, 2003 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis proposes a new simulated annealing approach to solve multiple objective sequencing problems in mixed-model assembly lines.
Mohammadi-Khashouie, Ghorbanali
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
The sequencing of agricultural market reforms in Malawi
The paper analyzes the welfare impacts of alternative sequencing scenarios of agricultural market reforms in Malawi using a profit maximization approach.
Kumaresan, Govindan, Kherallah, Mylène
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source