Results 91 to 100 of about 910,209 (262)

Hybrid de novo genome assembly and centromere characterization of the gray mouse lemur (Microcebus murinus)

open access: yesBMC Biology, 2017
Background The de novo assembly of repeat-rich mammalian genomes using only high-throughput short read sequencing data typically results in highly fragmented genome assemblies that limit downstream applications.
Peter A. Larsen   +19 more
doaj   +1 more source

$A$-sequences, $Z$-sequence, and $B$-sequences of Riordan Matrices

open access: yesDiscret. Math., 2019
We defined two type $B$-sequences of Riordan arrays and present the $A$-sequence characterization and $Z$-sequence characterization of the Riordan matrices with two type $B$-sequences. The subgroups characterized by $A$-sequences and $Z$-sequences are studied.
openaire   +4 more sources

Partitioning Sequencing Situations and Games [PDF]

open access: yes
The research that studies the interaction between sequencing situations and cooperative games, that started with the paper of Curiel et al. (1989), has become an established line of research.
Gerichhausen, M., Hamers, H.J.M.
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Characterization and Engineering of Two Novel Strand-Displacing B Family DNA Polymerases from Bacillus Phage SRT01hs and BeachBum

open access: yesBiomolecules
Polymerase-coupled nanopore sequencing requires DNA polymerases with strong strand displacement activity and high processivity to sustain continuous signal generation.
Yaping Sun   +6 more
doaj   +1 more source

On the Balancedness of Relaxed Sequencing Games [PDF]

open access: yes
This paper shows that some classes of relaxed sequencing games, which arise from the class of sequencing games as introduced in Curiel, Pederzoli, Tijs (1989), are balanced.sequencing situations;sequencing games;balancedness;game ...
Velzen, S. van, Hamers, H.J.M.
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

High-throughput PacBio library preparation and sequencing techniques for genomic DNA and TNA

open access: yesFrontiers in Genetics
PacBio Sequencing is an effective tool for achieving long read lengths to close gaps in whole genome assemblies. Limited information is available for automated, high-throughput library preparation workflows for PacBio sequencing. This paper describes two
Meghan L. Bentz   +5 more
doaj   +1 more source

Sequencing Games with Controllable Processing Time [PDF]

open access: yes
In this paper we study a class of cooperative sequencing games that arise from sequencing situations in which the processing times are not fixed.We show that these games are balanced by obtaining two core elements that depend only on the optimal schedule
Velzen, S. van
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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