Results 91 to 100 of about 910,209 (262)
Background The de novo assembly of repeat-rich mammalian genomes using only high-throughput short read sequencing data typically results in highly fragmented genome assemblies that limit downstream applications.
Peter A. Larsen +19 more
doaj +1 more source
$A$-sequences, $Z$-sequence, and $B$-sequences of Riordan Matrices
We defined two type $B$-sequences of Riordan arrays and present the $A$-sequence characterization and $Z$-sequence characterization of the Riordan matrices with two type $B$-sequences. The subgroups characterized by $A$-sequences and $Z$-sequences are studied.
openaire +4 more sources
Partitioning Sequencing Situations and Games [PDF]
The research that studies the interaction between sequencing situations and cooperative games, that started with the paper of Curiel et al. (1989), has become an established line of research.
Gerichhausen, M., Hamers, H.J.M.
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Polymerase-coupled nanopore sequencing requires DNA polymerases with strong strand displacement activity and high processivity to sustain continuous signal generation.
Yaping Sun +6 more
doaj +1 more source
On the Balancedness of Relaxed Sequencing Games [PDF]
This paper shows that some classes of relaxed sequencing games, which arise from the class of sequencing games as introduced in Curiel, Pederzoli, Tijs (1989), are balanced.sequencing situations;sequencing games;balancedness;game ...
Velzen, S. van, Hamers, H.J.M.
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
High-throughput PacBio library preparation and sequencing techniques for genomic DNA and TNA
PacBio Sequencing is an effective tool for achieving long read lengths to close gaps in whole genome assemblies. Limited information is available for automated, high-throughput library preparation workflows for PacBio sequencing. This paper describes two
Meghan L. Bentz +5 more
doaj +1 more source
Sequencing Games with Controllable Processing Time [PDF]
In this paper we study a class of cooperative sequencing games that arise from sequencing situations in which the processing times are not fixed.We show that these games are balanced by obtaining two core elements that depend only on the optimal schedule
Velzen, S. van
core
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

